A5101909737- Immunotherapy and Immune Responses
- Inhalation and Respiratory Drug Delivery
- Synthesis and Biological Evaluation
- Nerve injury and regeneration
- Electrospun Nanofibers in Biomedical Applications
- Tryptophan and brain disorders
- Nutrition and Health in Aging
- Cancer Immunotherapy and Biomarkers
- Diet and metabolism studies
- CRISPR and Genetic Engineering
- Muscle Physiology and Disorders
- Respiratory viral infections research
- Silk-based biomaterials and applications
- Vibrio bacteria research studies
- DNA and Nucleic Acid Chemistry
- Identification and Quantification in Food
- Immune Cell Function and Interaction
- Antibiotic Use and Resistance
- Pediatric health and respiratory diseases
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Extracellular vesicles in disease
- Cancer-related molecular mechanisms research
Pudong New Area People's Hospital
2023-2024
Northwest Women's and Children's Hospital
2023
University of South Carolina
2022
Huazhong University of Science and Technology
2020-2022
Chengdu Institute of Biology
2022
Chinese Academy of Sciences
2022
Union Hospital
2020
Severe ischemic stroke damages neuronal tissue, forming irregular-shaped cavities devoid of supporting structure. Implanting biomaterials to provide structural and functional support is thought favor ingrowth regenerated networks. Injectable hydrogels capable in situ gelation are often utilized for repair, but challenged by incomplete imprecise control over end-macrostructure. shape-memory scaffolds might overcome these limitations, not explored repair. Here, we report an injectable,...
Acute lung injury (ALI) is a life-threatening disease that currently lacks cure. Although stem cell-derived small extracellular vesicles (sEVs) have shown promising effects in the treatment of ALI, their underlying mechanisms and responsible components yet to be identified. Proprotein convertase subtilisin/kexin type 6 (PCSK6) gene involved inflammation potential target miR-21-5p, microRNA enriched sEVs. The current study investigated role PCSK6 lipopolysaccharide (LPS)-induced ALI its...
Regulatory T-cells (Tregs) play an important role in tumor immunosuppressive network, thus Tregs-targeted strategy is expected to enhance antitumor immunity and improve the effect of immunotherapy. Short peptide P60 can bind forkhead box protein P3 (Foxp3), a crucial transcriptional regulator for development inhibitory function Tregs, inhibit Foxp3 nuclear translocation Tregs. However, its treatment cancer limited due nonspecificity. Therefore, realizing specific delivery microenvironment...
Background: Viral pneumonia, a pressing global health issue, necessitates innovative therapeutic approaches. Acyclovir, potent ring-opening antiviral agent with broad-spectrum activity, faces water solubility, oral bioavailability, and drug resistance challenges. The aim of this study was to increase the efficacy acyclovir through respiratory delivery by encapsulating it within albumin-modified lipid nanoparticles formulate as spray. Methods: Nanoparticles synthesized via reverse evaporation...
In this study we amplified and sequenced the nearly complete mitochondrial DNA of an individual Liu’s skink, Plestiodon liui, from south Yangtze River. The obtained genome was 17, 945 bp in length, comprising 13 protein-coding genes (PCGs), 22 transfer RNA genes, two ribosomal incomplete control region (D-loop). Another mitogenome P. north River, retrieved GenBank used for comparative analyses. results showed that organization, base composition, codon usage, gene arrangement genomes...