A5057212614- Muscle Physiology and Disorders
- Cervical Cancer and HPV Research
- Reproductive tract infections research
- Menstrual Health and Disorders
- Menopause: Health Impacts and Treatments
- Genital Health and Disease
- Urological Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Genetics and Neurodevelopmental Disorders
- Prosthetics and Rehabilitation Robotics
- Urinary Tract Infections Management
- Cerebral Palsy and Movement Disorders
- Adolescent and Pediatric Healthcare
- Cardiomyopathy and Myosin Studies
- Endometriosis Research and Treatment
- Child Nutrition and Feeding Issues
- Neurogenetic and Muscular Disorders Research
- Fetal and Pediatric Neurological Disorders
- Ovarian function and disorders
- Pregnancy-related medical research
- Estrogen and related hormone effects
- Biomedical Ethics and Regulation
- Syphilis Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Female Genital Mutilation/Cutting Issues
National Center on Birth Defects and Developmental Disabilities
2015-2023
Centers for Disease Control and Prevention
2015-2023
RTI International
2019
Emory University
2019
Seattle Children's Hospital
2017
Children's Hospital of Los Angeles
2017
University of Michigan
2011-2014
Island Institute
2001-2010
Contraception Research and Development
2004-2009
Albert Einstein College of Medicine
2004
Care of children with spina bifida has significantly advanced in the last half century, resulting gains longevity and quality life for affected caregivers. Bladder dysfunction is norm patients may result infection, renal scarring chronic kidney disease. However, optimal urological management related bladder unknown.
Abstract Objective: The menopausal transition (MT) is a critical period associated with physiologic changes that influence women's long-term health and longevity. Information is, however, limited regarding factors age at the onset of MT its duration (ie, time from to final menstrual period). Methods: We analyzed data for 1,145 women four sites Study Women's Health Across Nation who participated in calendar substudy, had start identified, no missing covariate information. Participants...
To determine the natural history of bacterial vaginosis in women with or at risk for human immunodeficiency virus (HIV).A cohort 854 HIV-infected and 434 HIV-uninfected from four US sites was followed prospectively gynecologic exams every 6 months over a 5-year period. The prevalence, incidence, persistence, severity vaginosis, which defined using Gram-staining scoring system, were calculated generalized estimating equation methods.In adjusted analyses, had higher prevalence than (adjusted...
In Brief OBJECTIVE: To examine the association of highly active antiretroviral therapy (HAART) with human papillomavirus (HPV) clearance and progression or regression cervical cytological abnormalities in women immunodeficiency virus (HIV). METHODS: Five hundred thirty-seven HIV participating Epidemiology Research Study, an observational, multisite cohort study, were evaluated semiannually from 1996 to 2000. Cervical Pap tests collected for cytology. Testing HPV was conducted by polymerase...
In Brief OBJECTIVE: To evaluate the presence of and estimate risk factors for reactivation latent high-risk human papillomavirus (HPV) cervical infection in immunodeficiency virus (HIV)-infected HIV-uninfected women. METHODS: Data from 898 women HIV Epidemiology Research Study (HERS) were used to HPV latency reactivation. Prior exposure types (16, 18, 31, 35, 45) was determined by serologic testing at enrollment, shedding detected polymerase chain reaction 6-month intervals. Human sexual...
Duchenne and Becker muscular dystrophy are X-linked neuromuscular disorders characterized by progressive muscle degeneration. Despite the involvement of multiple systems, secondary conditions among affected males have not been comprehensively described. Two hundred nine caregivers (aged 3-31 years) identified Muscular Dystrophy Surveillance, Tracking, Research Network completed a mailed survey that included questions about impacting body functions. The 5 most commonly reported in with were...
In Brief OBJECTIVE: To compare the incidence of vulvar, vaginal, and perianal intraepithelial neoplasia among human immunodeficiency virus (HIV)–infected women with a group well-matched high-risk HIV-uninfected controls. METHODS: A total 192 HIV-infected 88 uninfected at high risk for HIV were followed up prospectively in Providence, Rhode Island during 6-year period. Pap tests cervicovaginal lavage papillomavirus detection typing performed baseline every 6 months thereafter. All referred...
To describe the occurrence of selected neurobehavioral concerns among males with a dystrophinopathy and to explore associations corticosteroid or supportive device use.Medical record abstraction was conducted for 857 affected from 765 families, born since 1982 followed through 2011, enrolled in population-based Muscular Dystrophy Surveillance, Tracking, Research Network. Cumulative probabilities attention-deficit hyperactivity disorder (ADHD), behavior problems, depressed mood were...
The lifetime risk of renal damage in children with spina bifida is high but only limited baseline imaging data are available for this population. We evaluated a large prospective cohort infants to define their characteristics.
Objective Previous studies describing menses duration and heaviness of flow during the menopausal transition ( MT ) have been short in limited to white women. We estimated frequency risk factors for prolonged bleeding, spotting heavy bleeding an ethnically diverse population. Design Prospective community‐based cohort study. Setting USA : southeastern Michigan, northern California Los Angeles, California. Population A total 1320 midlife women who participated Study Women's Health Across...
Background. Detection of atypical squamous cells undetermined significance (ASCUS) is a cervical cytologic finding that suggestive but not definitive intraepithelial lesions (SILs).
Duchenne and Becker muscular dystrophies, collectively referred to as dystrophinopathies, are recessive X-linked disorders characterized by progressive muscle weakness ultimately cardiac respiratory failure. Immediate family members often primary caregivers of individuals with a dystrophinopathy.We explored the impact this role inviting (n = 209) males diagnosed childhood-onset dystrophinopathy who were identified Muscular Dystrophy Surveillance, Tracking, Research Network (MD STARnet)...
Corticosteroids have been shown to improve muscle strength and delay loss of ambulation (LOA) in Duchenne muscular dystrophy (DMD) are considered standard care despite significant side-effects. The objective this study is evaluate whether corticosteroid treatment after LOA beneficial for cardiac or pulmonary functions among boys with DMD.We used the Muscular Dystrophy Surveillance, Tracking, Research Network (MD STARnet) characterize associations between use onset abnormal left ventricular...
Introduction: Racial/ethnic differences in diagnostic and treatment services have been identified for a range of health conditions outcomes. The current study aimed to analyze whether there are racial/ethnic the timing testing treatments males with Duchenne muscular dystrophy (DMD). Methods: Diagnostic clinical data male individuals DMD born during 1990–2010 were analyzed from eight sites (Arizona, Colorado, Georgia, Iowa, Piedmont Region North Carolina, Western New York, South Utah)...
We examined the accuracy of Papanicolaou (Pap) test among women with and at high risk for human immunodeficiency virus (HIV) infection.Pap results colposcopy findings were compared 189 HIV-infected 95 HIV-uninfected from Baltimore HIV Epidemiology Research (HER) study site who followed up semiannually 1993 through 1999. Correlations using data individual visits that analyzed generalized estimating equation methods.Among normal Pap tests underwent biopsy, likelihood cervical intraepithelial...
Quantifying associations between genetic mutations and loss of ambulation (LoA) among males diagnosed with childhood-onset dystrophinopathy is important for understanding variation in disease progression may be useful clinical trial design.
Objective This study aims to assess the agreement between menopausal transition stages defined by annual interviews or follicle-stimulating hormone levels and monthly menstrual calendars, as well factors associated with discordance. Methods These analyses used daily self-recorded calendar data from 1996 2006, interviews, levels. Participants were recruited four sites of Study Women's Health Across Nation (Boston, southeastern Michigan, Oakland, Los Angeles) racial/ethnic groups (African...
<b><i>Introduction:</i></b> Previous studies indicated variability in the prevalence of Duchenne and Becker muscular dystrophies (DBMD) by racial/ethnic groups. The Centers for Disease Control Prevention’s (CDC) Muscular Dystrophy Surveillance, Tracking, Research network (MD STAR<i>net</i>) conducts dystrophy surveillance multiple geographic areas USA continues to enroll new cases. This provides an opportunity continue investigating differences DBMD race...
To determine the frequency of and risk factors for abnormal vaginal Papanicolaou smears in HIV-infected women after hysterectomy. Data were from HIV Epidemiology Research (HER) study, a prospective multisite study uninfected women. Semiannual colposcopy data obtained 102 46 at-risk who had hysterectomy either before or during study. Analytic models used include Cox proportional hazards (women with study) multiple logistic regressions, which corrected repeated measures (all women). Among...
Purpose: Duchenne and Becker muscular dystrophies, collectively referred to as dystrophinopathies, are X-linked recessive diseases that affect dystrophin production resulting in compromised muscle function across multiple systems. The International Classification of Functioning, Disability Health provides a systematic classification scheme from which body functions affected by dystrophinopathy can be identified used examine functional health.Materials methods: infrastructure the Muscular...