J. Christopher Austin

ORCID: 0000-0002-4785-8093
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About
Contact & Profiles
Research Areas
  • Urological Disorders and Treatments
  • Pediatric Urology and Nephrology Studies
  • Urinary Bladder and Prostate Research
  • Ureteral procedures and complications
  • Urologic and reproductive health conditions
  • Congenital gastrointestinal and neural anomalies
  • Pelvic floor disorders treatments
  • Urinary Tract Infections Management
  • Bladder and Urothelial Cancer Treatments
  • Kidney Stones and Urolithiasis Treatments
  • Advanced X-ray and CT Imaging
  • Virus-based gene therapy research
  • Nuclear Physics and Applications
  • Geophysical and Geoelectrical Methods
  • Tissue Engineering and Regenerative Medicine
  • Urinary and Genital Oncology Studies
  • Gastrointestinal motility and disorders
  • Fetal and Pediatric Neurological Disorders
  • Testicular diseases and treatments
  • Thermal Regulation in Medicine
  • Medical Imaging Techniques and Applications
  • Spinal Dysraphism and Malformations
  • Electrostatics and Colloid Interactions
  • Vascular anomalies and interventions
  • Pain Mechanisms and Treatments

Oregon Health & Science University
2010-2025

Keele University
2001-2024

Doernbecher Children's Hospital
2019-2023

Oregon Medical Research Center
2020

University of Iowa
2002-2012

University of Iowa Health Care
2009

Southwestern Medical Center
2008

The University of Texas Southwestern Medical Center
2008

University of Toronto
1956-2008

University of Iowa Hospitals and Clinics
1998-2007

Care of children with spina bifida has significantly advanced in the last half century, resulting gains longevity and quality life for affected caregivers. Bladder dysfunction is norm patients may result infection, renal scarring chronic kidney disease. However, optimal urological management related bladder unknown.

10.1016/j.juro.2016.07.081 article EN The Journal of Urology 2016-07-28

Abstract Detecting defects within reinforced concrete is vital to the safety and durability of our built infrastructure upon which we heavily rely. In this work a non‐invasive technique, ElectroMagnetic Anomaly Detection (EMAD), used provides information into electromagnetic properties reinforcing steel for data analysis currently performed visually: an undesirable process. This article investigates first use two neural network approaches automate data: Echo State Networks (ESNs) Extreme...

10.1111/mice.12039 article EN Computer-Aided Civil and Infrastructure Engineering 2013-08-26

Questions regarding the efficacy and safety of long-term prophylactic antibiotics option minimally invasive therapy have increased clinical emphasis on predicting early resolution in patients with vesicoureteral reflux. We reviewed multiple potential prognostic factors addition to grade enhance predictive ability reflux resolution.Medical records cystograms from 324 children (257 girls 67 boys) primary were reviewed. Multiple analyzed respect outcome multivariable dependent tables...

10.1016/j.juro.2007.03.161 article EN The Journal of Urology 2007-08-18

Patients with neurogenic bladder dysfunction due to spina bifida have been reported be at increased risk for cancer. Recent publications suggest that augmentation is also a significant factor. We reviewed our experience treating patients and cancer.Patients treated cancer between 1995 2005 were identified. Patient demographics, mode of management, factors presenting symptoms recorded along therapy, pathological findings outcome. This patient cohort was combined all prior known published...

10.1016/j.juro.2007.05.055 article EN The Journal of Urology 2007-07-17

Children with daytime wetting often have constipation, and treatment of constipation helps children become dry. Polyethylene glycol 3350 (Miralax, Braintree Laboratories, Braintree, Massachusetts) is a nonaddictive, tasteless powder that can be mixed any liquid for constipation.We review our use polyethylene in 35 girls 11 boys dysfunctional elimination. Noninvasive urodynamic studies post-void residual measurement were performed before during treatment.A significant increase frequency bowel...

10.1097/01.ju.0000083730.70185.75 article EN The Journal of Urology 2003-10-01

SUMMARY Intravesical BCG therapy is effective in the treatment of superficial bladder cancer. Both clinical and experimental results suggest a role for cytokines delayed-type hypersensitivity (DTH) BCG-induced antitumour immunity. We characterized modulatory effects on cytokine expression determined relationship between DTH activity. The bladders mice were instilled with through catheter. Bladder tissue RNA urine collected evaluation using reverse transcriptase-polymerase chain reaction...

10.1046/j.1365-2249.2003.02071.x article EN Clinical & Experimental Immunology 2003-01-31

Mice with gene deletion or targeted over expression are important for understanding the remodeling that follows partial bladder outlet obstruction (PBOO). This condition predominates in males. We produced PBOO male mice and now report physiological, histological molecular consequences.Male C57bl/6 were surgically obstructed subjected to sham surgery unoperated served as controls. Four weeks later bladders excised their function was assessed vitro whole cystometry. The optimum volume pressure...

10.1097/01.ju.0000138045.61378.96 article EN The Journal of Urology 2004-09-15

No AccessJournal of UrologyPEDIATRIC UROLOGY1 Sep 2003Do Public Schools Teach Voiding Dysfunction? Results an Elementary School Teacher Survey CHRISTOPHER S. COOPER, CHADI T. ABOUSALLY, J. AUSTIN, MARGARET A. BOYT, and CHARLES E. HAWTREY COOPERCHRISTOPHER COOPER , ABOUSALLYCHADI ABOUSALLY AUSTINJ. AUSTIN BOYTMARGARET BOYT HAWTREYCHARLES View All Author Informationhttps://doi.org/10.1097/01.ju.0000075916.55446.eeAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack...

10.1097/01.ju.0000075916.55446.ee article EN The Journal of Urology 2003-09-01

No AccessJournal of UrologyClinical research1 Oct 2007Computational Model for Predicting the Chance Early Resolution in Children With Vesicoureteral Reflux Matthew J. Knudson, Christopher Austin, Moshe Wald, Antoine A. Makhlouf, Craig S. Niederberger, and Cooper KnudsonMatthew Knudson Division Pediatric Urology, Department University Iowa, Iowa City, , AustinJ. Austin WaldMoshe Wald MakhloufAntoine Makhlouf Minnesota, Minneapolis, Minnesota NiederbergerCraig Niederberger Illinois at Chicago,...

10.1016/j.juro.2007.05.093 article EN The Journal of Urology 2007-08-18

Renal ultrasounds are performed in patients with myelomeningocele to screen for markers of kidney health, including hydronephrosis. We evaluated the diagnostic accuracy hydronephrosis low function defined by estimated glomerular filtration rate (eGFR). a retrospective cross-sectional study using data from 2 cohorts children and youth myelomeningocele. The first cohort is Urological Management Preserve Initial Function Protocol Young Children With Spina Bifida (UMPIRE; 2016-2022) second...

10.1097/ju.0000000000004342 article EN The Journal of Urology 2025-02-07

We compared 2 treatment modalities (sling cystourethropexy and periurethral collagen injection) in patients with intrinsic sphincter deficiency alone or urethral hypermobility (combined stress urinary incontinence).We retrospectively reviewed a series of 50 consecutive treated surgically for during 2-year period. All were evaluated by history physical examination to assess urodynamic testing. Intrinsic was assessed abdominal leak point pressure video urodynamics. Of the 28 underwent...

10.1016/s0022-5347(01)65413-2 article EN The Journal of Urology 1996-12-01

There is currently no curative therapy for men who have disseminated prostate cancer following failed radical prostatectomy. The purpose of this trial was to investigate systemic radioimmunotherapy in these men. Eight patients with occult metastatic prostatectomy as evidenced solely by a rising serum PSA and evidence soft tissue lesions outside the prostatic fossa detected an [111I]indiumcapromab pendetide scan received infusion 10 mg capromab labeled 9 mCi/m2 [90Y]yttrium. Serum used...

10.1089/cbr.1999.14.99 article EN Cancer Biotherapy and Radiopharmaceuticals 1999-04-01

Reflux grade is the factor most commonly used to predict spontaneous reflux resolution. We evaluated other potential predictive factors aside from relative resolution.We reviewed records of 20 males and 98 females who were diagnosed with primary vesicoureteral between ages 0 7 years 1990 2000. Age, sex, height, weight, grade, bladder volume at onset laterality recorded for first, second recent voiding cystourethrogram or nuclear cystogram before resolution operative intervention.Of 118...

10.1016/s0022-5347(06)00619-7 article EN The Journal of Urology 2006-08-31

Limited studies suggest a relationship between scarring on renal scan and failure to resolve vesicoureteral reflux. We evaluated the impact of abnormal scans early reflux resolution.The medical records were reviewed children diagnosed with primary 1988 2004. defined an as or relative function 40% less. Reflux resolution was noted 1 2 years after diagnosis.Renal data available 161 reflux, including 127 girls 34 boys. Relative 15% less in 7 children, 16% 35% 14, 36% 18 greater than 122. Of...

10.1016/j.juro.2008.03.102 article EN The Journal of Urology 2008-10-01

We evaluated pediatric patients who were treated with biofeedback for dysfunctional voiding respect to clinical outcome and objective changes in uroflow parameters post-void residual.We retrospectively reviewed 81 and/or urinary tract infections biofeedback. Conservative management had previously failed all patients. Uroflow data symptoms reviewed, outcomes recorded. For analysis, stratified by of incontinence or presence infections.Of 73 22 (30%) became dry, 36 (49%) improvement 15 (21%)...

10.1097/01.ju.0000138872.14641.40 article EN The Journal of Urology 2004-09-15

Assessment of first febrile urinary tract infection in young children has usually involved 2 imaging techniques: renal ultrasonogram and voiding cystourethrography. Currently, there is growing interest using the dimercaptosuccinic acid (DMSA) scan labeled with technetium-99m as an alternative initial study, evaluation UTI. DMSA scanning most sensitive radiologic study to detect acute pyelonephritis. Early been called top-down approach, because focus identification kidney injury rather than...

10.1097/inf.0b013e318168d26f article EN The Pediatric Infectious Disease Journal 2008-04-28
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