Identification of patients at risk death from cancer surgery should aid in preoperative preparation. The purpose this study is to assess and adjust the age-adjusted Charlson comorbidity index (ACCI) identify with increased perioperative mortality.We identified 156,151 undergoing for one ten common cancers between 2007 2011 Taiwan National Health Insurance Research Database. Half were randomly selected, a multivariate logistic regression analysis was used develop an adjusted-ACCI score...

This population-based study investigated the relationship between individual and neighborhood socioeconomic status (SES) mortality rates for major cancers in Taiwan.A follow-up was conducted with 20,488 cancer patients diagnosed 2002. Each patient traced to death or 5 years. The income-related insurance payment amount used as a proxy measure of SES patients. Neighborhood defined by income, neighborhoods were grouped living advantaged disadvantaged areas. Cox proportional hazards model...

Purpose The aim of this study was to develop a multivariate logistic regression model with least absolute shrinkage and selection operator (LASSO) make valid predictions about the incidence moderate-to-severe patient-rated xerostomia among head neck cancer (HNC) patients treated IMRT. Methods Materials Quality life questionnaire datasets from 206 HNC were analyzed. European Organization for Research Treatment Cancer QLQ-H&N35 QLQ-C30 questionnaires used as endpoint evaluation. primary (grade...

We studied the effect of Age-Adjusted Comorbidity Index Score in colorectal cancer patients who underwent similarly aggressive treatment. Using National Health Insurance Research Database Taiwan, we identified 5643 with surgical resection and chemoradiation from 2007 through 2011. estimated survival according to Scores 5-year using Cox proportional hazard regression analysis, adjusting for sex, oxaliplatin-based chemotherapy, socioeconomic status, geographic region, hospital characteristics....

Triple-negative breast cancer (TNBC) is the most aggressive and fatal subtype. Nowadays, chemotherapy remains standard treatment of TNBC, immunotherapy has emerged as an important alternative. However, high rate TNBC recurrence suggests that new desperately needed. Schisandrin B (Sch B) recently revealed its anti-tumor effects in cancers such cholangiocarcinoma, hepatoma, glioma, multi-drug-resistant cancer. there still a need to investigate using Sch treatment. Interleukin (IL)-1β,...

BackgroundOral cancer leads to a considerable use of health care resources. Wide resection the tumor and reconstruction with pedicle flap/ free flap is widely used. This study was conducted investigate if young age at time diagnosis oral requiring this treatment confers worse prognosis. MethodsA total 2339 patients who underwent resections for from 2004 2005 were identified The Taiwan National Health Insurance Research Database. Survival analysis, Cox proportional regression model,...

Although palliative chemotherapy during end-of-life care is used for relief of symptoms in patients with metastatic cancer, may lead to more aggressive and less use hospice service. This a population-based study the association between aggressiveness care.Using National Health Insurance Research Database Taiwan, we identified 49,920 cancer who underwent from January 1, 2009, December 31, 2011. Patients received 2-6 months before death were included. Aggressiveness was examined by previously...

Vegetarian diets may lower symptomatic gallstone disease via cholesterol lowering. This study aimed to examine the risk of (GSD) in Taiwanese vegetarians vs. nonvegetarians a prospective cohort and explore if this association is related concentration. We prospectively followed 4839 participants, 29,295 person-years follow-up, 104 new incident GSD cases were confirmed. Diet was assessed through validated food frequency questionnaire. Symptomatic ascertained linkage Taiwan National Health...

Positive results between caseloads and outcomes have been validated in several procedures cancer treatments. However, there is limited information available on the combined effects of surgeon hospital caseloads. We used nationwide population-based data to explore association survival rates for major cancers.A total 11,677 patients with incident diagnosed 2002 were identified from Taiwan National Health Insurance Research Database. Survival analysis, Cox proportional hazards model, propensity...

Purpose Gastric cancer is a leading cause of death, particularly in the developing world. The literature reports individual socioeconomic status (SES) or neighborhood SES as related to survival, but effect both has not been studied. This study investigated and simultaneously on mortality gastric patients Taiwan. Materials Methods A was conducted 3,396 diagnosed with between 2002 2006. Each patient followed for five years until death. Individual defined by income-related insurance premium...

Abstract Background. The relationship between low socioeconomic status (SES) and aggressiveness of end-of-life (EOL) care in cancer patients working age (older than 18 years younger 65 years) is not clear. We assessed the association EOL differences SES among working-age terminal from Taiwan 2009 2011. Methods. A total 32,800 deaths were identified National Health Insurance Research Database. indicators aggressive (chemotherapy, more one emergency room [ER] visit or hospital admission, 14...

Hepatocellular carcinoma (HCC) is an aggressive malignant tumor with a high mortality rate. The optimal therapeutic choice for early HCC surgical resection. However, the rate of intrahepatic recurrence high. objective this study was to evaluate effect various factors on survival patients HCC. Between January 1st, 2006 and December 31st, 2013, total 89 who underwent surgery were retrospectively enrolled. analysis conducted using Student's t-test, Chi-square test, Kaplan-Meier method Cox...

In this study, we designed and manufactured a posterior lumbar interbody fusion cage for osteoporosis patients using 3D-printing. The structure conforms to the anatomical endplate's curved surface stress transmission internal lattice design bone growth. Finite element (FE) analysis weight topology optimization under different spine activity ratios were integrated (CS-type) endplate morphology statistical results from patients. CS-type plate (P-type) biomechanical behaviors daily activities...

The gut microbiota has been implicated in many cancers through the secretion of blood-traveling metabolites or activation oncogenic signaling. Currently, specific microbial signatures have detected human breast, which are different from other microbial-rich compartments, such as intestine and skin. Changes breast microbiome profile shown to positively negatively correlate with cancer development, progression, therapeutic outcomes. However, studies regarding role underlying mechanism...

Esophageal cancer is the sixth leading cause of mortality. More than 90% patients with esophageal in Taiwan have squamous cell carcinoma. Survival such related to socioeconomic status (SES). We studied association between SES (individual and neighborhood) survival working-age Taiwan. A population-based study was conducted 4097 diagnosed 2002 2006. Each traced for 5 years or until death. Individual defined by enrollee job category. Neighborhood based on household income dichotomized into...

The relationship between individual and neighborhood socioeconomic status (SES) mortality rates in patients with nasopharyngeal carcinoma (NPC) is unknown. This population-based study aimed to examine the association SES survival of NPC Taiwan.A follow-up was conducted 4691 diagnosed 2002 2006. Each patient traced death or for 5 years. Individual defined by enrollee job category. Neighborhood based on household income dichotomized into advantaged disadvantaged areas. Cox proportional hazards...

The influence of different hospital and surgeon volumes on short-term survival after hepatic resection is not clearly clarified. By taking the known prognostic factors into account, purpose this study to assess combined effects volume resection.13,159 patients who underwent between 2002 2006 were identified in Taiwan National Health Insurance Research Database. Data extracted from it survivals confirmed through 2006. Cox proportional hazards model was used relationship hospital, caseload...

The impact of important preexisting comorbidities, such as liver and renal disease, on the outcome resection remains unclear. Identification patients at risk mortality will aid in improving preoperative preparations. purpose this study is to develop validate a population-based score based available predictable parameters predicting 90-day after using data from hepatitis endemic country. We identified 13,159 who underwent between 2002 2006 Taiwan National Health Insurance Research Database....

Abstract Little is known regarding the association of non-lactational mastitis women with breast cancer risk. This population-based cohort study examined risk in mastitis. We identified 3,091 between 2000 and 2011 using Taiwan National Health Insurance Research Database. performed 1:4 propensity score matching by age, socioeconomic status comorbidities 12,364 without The mean age was 37.9 years; these had a higher than comparison group (adjusted hazard ratio = 1.94, 95% confidence interval:...

Lymph node yield is recommended as a benchmark of quality care in colorectal cancer. The objective this study was to evaluate the impact various factors upon lymph and identify independent associated with harvest.The records 162 patients Stage I III cancers seen one institution were reviewed. These underwent radical surgery definitive therapy; high-risk then received adjuvant treatment. Pathologic demographic data recorded analyzed. subgroup analysis yields determined using t-test variants....