Xu Wan

ORCID: 0009-0002-2722-0129
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About
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Research Areas
  • Protein Structure and Dynamics
  • Computational Drug Discovery Methods
  • Bioinformatics and Genomic Networks
  • Smart Grid Security and Resilience
  • Literary Theory and Cultural Hermeneutics
  • Industrial Technology and Control Systems
  • Microbial Natural Products and Biosynthesis
  • Target Tracking and Data Fusion in Sensor Networks
  • Radiopharmaceutical Chemistry and Applications
  • Diet, Metabolism, and Disease
  • Non-Invasive Vital Sign Monitoring
  • Diabetes Management and Education
  • Machine Learning in Materials Science
  • Soft Robotics and Applications
  • Smart Grid Energy Management
  • Monoclonal and Polyclonal Antibodies Research
  • Quantum Dots Synthesis And Properties
  • Magnetic and Electromagnetic Effects
  • Electrostatic Discharge in Electronics
  • Inertial Sensor and Navigation
  • Antibiotic Resistance in Bacteria
  • Contemporary Literature and Criticism
  • Vehicle emissions and performance
  • Global Maternal and Child Health
  • Gold and Silver Nanoparticles Synthesis and Applications

Shenzhen Academy of Robotics
2024

Tianjin University
2024

Shanghai Jiao Tong University
2021-2023

Zhejiang University
2023

State Key Laboratory of Industrial Control Technology
2022

Renji Hospital
2021

Zhejiang A & F University
2016

Qilu Hospital of Shandong University
2015

Hubei University
2013

Northeastern University
2007

The decarbonization of energy systems has posed unprecedented challenges in system complexity and operational uncertainty that render it imperative to exploit cutting-edge artificial intelligence (AI) technologies realize real-time, autonomous power operation control. In particular, deep reinforcement learning (DRL)-based approaches are extensively studied implemented several trials worldwide. Nevertheless, the vulnerability DRL brings new security threats have not been well identified...

10.1109/tpwrs.2022.3192558 article EN IEEE Transactions on Power Systems 2022-07-20

Binding affinity prediction of three-dimensional (3D) protein-ligand complexes is critical for drug repositioning and virtual screening. Existing approaches usually transform a 3D complex to two-dimensional (2D) graph, then use graph neural networks (GNNs) predict its binding affinity. However, the node edge features 2D are extracted based on invariant local coordinate systems complex. As result, these can not fully learn global information complex, such as physical symmetry topological...

10.1109/jbhi.2024.3383245 article EN IEEE Journal of Biomedical and Health Informatics 2024-03-29

With the increasing penetration of inverter-based renewable energy resources, deep reinforcement learning (DRL) has been proposed as one most promising solutions to realize real-time and autonomous control for future carbon-neutral power systems. In particular, DRL-based frequency approaches have extensively investigated overcome limitations model-based approaches, such computational cost scalability large-scale Nevertheless, real-world implementation DRLbased methods is facing following...

10.1609/aaai.v37i4.25660 article EN Proceedings of the AAAI Conference on Artificial Intelligence 2023-06-26

Objective: Nesfatin-1, originates from the precursor protein nucleobindin 2 (NUCB2) and plays an important role in development of metabolic syndrome (MetS), including obesity hypertension. This study aimed to determine whether 1012C>G polymorphism NUCB2 gene is correlated with MetS Chinese Han population. Materials Methods: The was detected a population 326 patients 165 healthy subjects. Results: showed lower CG GG genotypes, as well G allele frequencies, compared Unconditional logistic...

10.1089/gtmb.2015.0194 article EN Genetic Testing and Molecular Biomarkers 2015-12-01

With the increase in drug resistance rates of pathogens isolated from complicated intra-abdominal infections (cIAIs), ceftazidime/avibactam (CAZ-AVI) is increasingly used clinically. However, given high cost and fact that not yet covered by health insurance payment, this study evaluated cost-effectiveness CAZ-AVI plus metronidazole versus meropenem as a first-line empiric treatment for cIAIs perspective Chinese healthcare system.A decision analytic model with one-year time horizon was...

10.1016/j.jiph.2023.01.008 article EN cc-by-nc-nd Journal of Infection and Public Health 2023-01-19

Predicting the docking between proteins and ligands is a crucial challenging task for drug discovery. However, traditional methods mainly rely on scoring functions, deep learning-based approaches usually neglect 3D spatial information of ligands, as well graph-level features which limits their performance. To address these limitations, we propose an equivariant transformer neural network protein-ligand pose prediction. Our approach involves fusion ligand by feature processing, followed...

10.48550/arxiv.2310.08061 preprint EN other-oa arXiv (Cornell University) 2023-01-01

We stimulated the exposed toad heart by a low frequency and high energy magnetic. By analyze data of this experiment, it shows that pulsating weak would make change after Weak heartbeat strengthened, single peak curve become two peaks with atria wave ventricle magnetic stimulation. But cycling rhythmic pulsatile doesn't change.

10.1109/iccme.2007.4382081 article EN IEEE/ICME International Conference on Complex Medical Engineering 2007-05-01
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