- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Cellular transport and secretion
- Fungal and yeast genetics research
- Monoclonal and Polyclonal Antibodies Research
- HER2/EGFR in Cancer Research
- Plant Disease Resistance and Genetics
- Glycosylation and Glycoproteins Research
- Plant Disease Management Techniques
- Endoplasmic Reticulum Stress and Disease
- Bacterial Genetics and Biotechnology
- Spectroscopy and Chemometric Analyses
- Plant Reproductive Biology
- Radiomics and Machine Learning in Medical Imaging
- Ion channel regulation and function
- Molecular Biology Techniques and Applications
- Microbial Community Ecology and Physiology
- Bacteriophages and microbial interactions
University of Illinois Chicago
1997-2007
Igenbio (United States)
2001
University of Wisconsin–Madison
1991
The eukaryotic family of ADP-ribosylation factor (Arf) GTPases plays a key role in the regulation protein trafficking, and guanine-nucleotide exchange is crucial for Arf function. Exchange stimulated by members another proteins characterized 200-amino acid Sec7 domain, which alone sufficient to catalyze on Arf. Here, we analyzed phylogeny Sec7-domain-containing seven model organisms, representing fungi, plants, animals. phylogenetic tree has main groups, two include from all systems. Three...
Using computer programs developed for this purpose, we searched various repeated sequences including inverted, direct tandem, and homopurine–homopyrimidine mirror repeats in prokaryotes, eukaryotes, an archaebacterium. Comparison of observed frequencies with expectations revealed that bacterial genomes organelles the frequency different is either random or enriched inverted and/or tandem repeats. By contrast, all eukaryotic studied, overrepresentation repeats, especially Analysis genomic...
We previously demonstrated that quantitative immunohistochemistry (Q-IHC) performed by measuring the cumulative signal strength of digital file encoding an image can be used to determine absolute amount chromogen present per pixel. now show Q-IHC so accurately peptide hormone receptor interest in archived tissues. To do this we transfected Balb 3T3 fibroblasts with cDNA human for gastrin-releasing (GRP), and selected six cell lines stably expressing between 10 2 6 receptors/cell. These were...
Abstract Background Ypt/Rab GTPases and their GEF activators regulate intra-cellular trafficking in all eukaryotic cells. In S. cerivisiae , the modular TRAPP complex acts as a for Golgi gatekeepers: Ypt1 functional pair Ypt31/32. While TRAPPI, which early Golgi, is conserved from fungi to animals, not much known about TRAPPII, late consists of TRAPPI plus three additional subunits. Results Here, we show phylogenetic analysis TRAPPII-specific One copy each two essential subunits, Trs120...
Abstract Three populations of Arabidopsis thaliana (L.) Heynh. were inoculated with three isolates Plasmodiophora brassicae Woron. Inoculation young plants caused clubbing roots and, in the late flowering population CrGC 9–4, infection shoots. In this population, number reaching stage was reduced, and majority died prematurely. Symptoms shoot infections compressed rosettes thickened stunted leaves containing resting spores P. . The results showed clearly that A. is susceptible to