A5008628936- Anesthesia and Pain Management
- Spine and Intervertebral Disc Pathology
- Pain Mechanisms and Treatments
- Pain Management and Opioid Use
- Cancer Treatment and Pharmacology
- Musculoskeletal pain and rehabilitation
Daiichi-Sankyo (Japan)
2022-2024
Abstract Background For chronic pain after thoracic surgery, optimal timing of its diagnosis and effective treatment remains unresolved, although several options are currently available. We examined the efficacy safety mirogabalin, in combination with conventional therapy (nonsteroidal anti-inflammatory drugs and/or acetaminophen), for treating peripheral neuropathic (NeP) surgery. Methods In this multicenter, randomized, open-label, parallel-group study, patients NeP were randomly assigned...
In Japan, conservative therapy for patients with lumbar spinal stenosis (LSS) includes non-steroidal anti-inflammatory drugs (NSAIDs), prostaglandin E1, tramadol, physical/exercise therapy, and nerve blocks. Mirogabalin, a selective oral α2δ ligand, is approved treating peripheral neuropathic pain, though data regarding visual analog scores (VAS) pain in LSS are limited. We investigated the efficacy safety of mirogabalin as an add-on treatment taking NSAIDs compared only. This multicenter,...