- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- CAR-T cell therapy research
- Clinical practice guidelines implementation
- Multiple Myeloma Research and Treatments
- COVID-19 and healthcare impacts
- Peptidase Inhibition and Analysis
- Cancer Treatment and Pharmacology
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Ion channel regulation and function
- Allergic Rhinitis and Sensitization
- Thyroid Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Musculoskeletal pain and rehabilitation
- Histone Deacetylase Inhibitors Research
- Vitamin D Research Studies
- Dermatology and Skin Diseases
- Vaccine Coverage and Hesitancy
- Cutaneous Melanoma Detection and Management
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
- Children's Rights and Participation
- Hematopoietic Stem Cell Transplantation
- Healthcare cost, quality, practices
College of Family Physicians of Canada
2023-2025
Doug Bragg Enterprises (Canada)
2024
Northwestern University
2024
The University of Texas Medical Branch at Galveston
2024
Memorial Sloan Kettering Cancer Center
2021-2023
Newcastle upon Tyne Hospitals NHS Foundation Trust
2021-2023
Lawrence Berkeley National Laboratory
2021
Iowa State University
2014
Western University
2002
Immune recovery post–cellular therapies is an important predictor of response to the anti–SARS-CoV-2 vaccine and can be used guide timing primary vaccination, as well booster vaccine, after therapy.
To develop a clinical practice guideline to support the management of chronic pain, including low back, osteoarthritic, and neuropathic pain in primary care.The was developed with an emphasis on best available evidence shared decision-making principles. Ten health professionals (4 generalist family physicians, 1 management-focused physician, anesthesiologist, physical therapist, pharmacist, nurse practitioner, psychologist), patient representative, nonvoting pharmacist methodologist...
Family medicine physicians manage the highest complexity of conditions in their practices.[1][1] must actively stay up to date on new advances and recent evidence; care for patients all ages throughout many stages lives; share patients' struggles triumphs
To update the 2015 clinical practice guideline and provide a simplified approach to lipid management in prevention of cardiovascular disease (CVD) for primary care.Following Institute Medicine's Clinical Practice Guidelines We Can Trust, multidisciplinary, pan-Canadian panel was formed. This represented by care providers, free from conflicts interest with industry, included patient perspective. A separate scientific evidence team performed reviews on statins, ezetimibe, proprotein convertase...
Real-world data on the efficacy and tolerability of isatuximab with pomalidomide dexamethasone (IsaPomDex) in relapsed/refractory myeloma patients have not been reported. In this UK-wide retrospective study, IsaPomDex outcomes were evaluated across 24 routine care cancer centers. The primary endpoint was overall response rate (ORR). Secondary endpoints included progression-free survival (PFS), duration (DOR) for who achieved an objective (≥partial [PR]), adverse events (AEs). a total cohort...
Actualiser le guide de pratique clinique 2015 et présenter une approche simplifiée la prise en charge des lipides dans prévention maladies cardiovasculaires (MCV) première ligne. MÉTHODES: Conformément aux recommandations l’Institute of Medicine
Blood culture contamination is a major problem in health care, with significant impacts on both patient safety and cost. Initiatives to reduce blood require reliable, consistent metric track the success of interventions. The objective our project was establish standardized definition suitable for use Veterans Health Administration (VHA) national data query, then validate this query. A secondary construct VHA dashboard display from query that could be used quality improvement projects aimed...
Objectives There are no real-world data describing infection morbidity in relapsed/refractory myeloma (RRMM) patients treated with anti-CD38 isatuximab combination pomalidomide and dexamethasone (IsaPomDex). In this UK-wide retrospective study, we set out to evaluate infections experienced by routine care who received novel therapy across 24 cancer centres during the COVID-19 pandemic.Methods The primary endpoint was (incidence, grading, hospitalization) as well infection-related deaths....
What are the benefits and risks of 3 coronavirus disease 2019 (COVID-19) vaccines? Interim results (2 large RCTs) show relative efficacy Pfizer-BioNTech Moderna vaccines (about 95%) AstraZeneca-Oxford vaccine 70%) in preventing COVID-19. Absolute will vary
Formuler des lignes directrices de pratique clinique pour soutenir la prise en charge douleur chronique, y compris lombaire, arthrosique et neuropathique, dans les soins primaires. MÉTHODES: Ces ont été élaborées mettant l’accent sur meilleures données probantes disponibles principes décision partagée. Dix professionnels santé (4 omnipraticiens, 1 médecin famille spécialisée gestion douleur, anesthésiste, physiothérapeute, pharmacienne, infirmière praticienne psychologue), représentant...
ABSTRACT Introduction Relatives of a victim sudden cardiac death in the young (SCDY) may be at risk for hereditary cardiomyopathies and arrhythmias. Family leaders are often responsible communicating to surviving family difficult time. Purpose Explore barriers facilitators communication about cascade screening families who have lost member SCDY Methods Semi-structured interviews (n = 14) were conducted with members decedent. Participants recruited from Sudden Arrhythmia Death Syndrome...
En soins primaires, l'une des consultations les plus courantes a pour motif une infection voies urinaires (IVU) sans complication, décrite par patients comme fréquence urinaire accrue, dysurie, envie urgente, miction incomplète ou hématurie. Elle est généralement