A5085071827- Electrospun Nanofibers in Biomedical Applications
- Osteoarthritis Treatment and Mechanisms
- Proteoglycans and glycosaminoglycans research
- Silk-based biomaterials and applications
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Hydrogels: synthesis, properties, applications
- Connective tissue disorders research
- Spectroscopy and Quantum Chemical Studies
- Wound Healing and Treatments
- Collagen: Extraction and Characterization
- Advanced Chemical Physics Studies
- Tendon Structure and Treatment
- Protease and Inhibitor Mechanisms
- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Animal Nutrition and Physiology
- Urological Disorders and Treatments
- Knee injuries and reconstruction techniques
- Biopolymer Synthesis and Applications
- Bone health and osteoporosis research
- Exercise and Physiological Responses
- Polysaccharides Composition and Applications
- Titanium Alloys Microstructure and Properties
- Liver physiology and pathology
University of Padua
1999-2024
The tolerability and safety of hyaluronan-based three-dimensional scaffolds as a culture vehicle for mesenchymal progenitor cells was investigated in this pilot study. proliferation patterns extracellular matrix production rabbit human mesenchymal, bone-marrow-derived progenitors first were characterized vitro. Subsequently autologous cultured scaffold implanted full-thickness osteochondral lesion. In vitro histologic findings showed that adhered proliferated onto the hyaluronan-derived...
The effect of the intraarticular sodium hyaluronate (HA) injection on osteoarthritic knee joint has been evaluated in dogs using an experimental model osteoarthritis induced by sectioning anterior cruciate ligament. Seven weeks after surgery, damage, graded according to Mankin's scale, was significantly reduced joints treated with HA from second week postsurgery compared untreated joints. When therapy initiated seventh week, progression still controls. Both morphology and morphometry showed...
SUMMARY— Histological and chemical studies were carried out on the elastin collagen content of normal obstructed urinary bladder wall. The observations made 3 different age groups: (1) 3‐month‐old children with vesical outlet obstruction, (2) aged between 4 8 years partial (3) adults a chronically bladder. An increase in elastic tissue was shown only newborn adults. did not vary any cases studied. showed an polar amino acids pathological organs compared normal. A similar observed individuals...
The present study describes the production of hyaluronan based porous microparticles by a semi-continuous gas anti-solvent (GAS) precipitation process to be used as growth factor delivery system for in vivo treatment ulcers. Operative conditions, such pressure, nozzle diameter and HYAFF11® solution concentrations, were adjusted optimize particle terms morphology size. Scanning electron microscopy (SEM) light scattering demonstrated that nano-structured particles with size 300 900 nm had high...
An established anterior cruciate ligament deficiency- induced articular cartilage degeneration was used to evaluate the effects of intrasynovial injection hyaluronic acid upon destruction. In this study, proteoglycan solubility under associative and dissociative conditions compared in two treatment protocols at intervals seven, 13, 17 weeks after surgical breakage 2.5-year-old Beagle dogs. Untreated joints showed a marked increase both total soluble glycosaminoglycan (GAG measured as uronic...
Abstract In this study we coated a new biocompatible, nanostructured titanium alloy, Ti13Nb13Zr, with thin layer of hydroxyapatite nanocrystals and investigated the response human bone‐marrow‐derived mesenchymal cells. The coating was realized using slightly supersaturated CaP solution, which provokes fast deposition nanocrystalline hydroxyapatite. A is appreciable on etched Ti13Nb13Zr substrates after just 1.5 h soaking in it reaches thickness 1–2 μm 3 soaking. seems thinner than that...
AIMS--The objective of this study was to investigate alterations in conjunctival collagen and proteoglycans the giant papillae patients with vernal keratoconjunctivitis (VKC). METHODS--Tissue samples from tarsal seven eyes five VKC, normal were obtained. Tissues processed stained haematoxylin eosin, Van Gieson, trichromic Mallory, toluidine blue, Alcian alkaline Giemsa. Collagen extraction performed acetic acid pepsin, total quantified using hydroxy-proline levels, types I III analysed by...
The tolerability and safety of hyaluronan-based three-dimensional scaffolds as a culture vehicle for mesenchymal progenitor cells was investigated in this pilot study. proliferation patterns extracellular matrix production rabbit human mesenchymal, bone-marrow-derived progenitors first were characterized vitro. Subsequently autologous cultured scaffold implanted full-thickness osteochondral lesion. In vitro histologic findings showed that adhered proliferated onto the hyaluronan-derived...
Using chemical and histochemical techniques, it has been possible to calculate the exact amount distribution of elastin in normal abnormal ureters children. From quantitative analyses, calculated that dilated content represents 3% 5% organic material, while is less than 1%.