A5091983940- Neuroinflammation and Neurodegeneration Mechanisms
- Barrier Structure and Function Studies
- Bacterial Infections and Vaccines
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Tryptophan and brain disorders
- Alzheimer's disease research and treatments
Colorado State University
2023-2024
Tuberculosis, caused by Mycobacterium tuberculosis infection, is an ongoing epidemic with estimated ten million active cases of the disease worldwide. Pulmonary associated cognitive and memory deficits, patients this are at increased risk for Parkinson's dementia. Although epidemiological data correlates neurological effects peripheral disease, pathology in central nervous system unknown. In established guinea pig model low-dose, aerosolized we see behavior changes loss infected animals. We...
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, is a chronic inflammatory disease. Although typically associated with inflammation of the lungs and other peripheral tissues, increasing evidence has uncovered neurological consequences attributable to Mtb infection. These include deficits in memory cognition, increased risk for neurodegenerative disease, progressive neuropathology. effects without CNS have been characterized, mechanism neurotoxicity unknown. We...