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R. A. Ryanzhina

ORCID: 0009-0002-9370-3866
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A5093771772
Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Cancer Immunotherapy and Biomarkers
  • Genetic factors in colorectal cancer
  • Endometriosis Research and Treatment

State Budget Institution of Health St. Petersburg Clinical Research Center Specialized Types of Medical Care
 2024

 Efficacy and safety of lenvatinib and pembrolizumab in the treatment of endometrial cancer: data from routine clinical practice in Russia
OPENALEX - Publications 
A. А. Rumyantsev А. Э. Протасова M. Sheremet А. Yu. Goryainova Mikhail V. Volkonskiy and 54 more А. Г. Кедрова S. V. Kuzmicheva O. N. Aymamedova Х. С. Мусаева Svetlana Soroka Olha Romanchuk V. N. Orlova N. G. Graft Mavluda Ibragimova Yu. I. Merzlikina L. V. Stepura L. B. Tatulova A. A. Abasova A. A. Akopyan E. V. Arsenyeva Yu. V. Vasilyeva А. В. Белоногов Л. В. Криволапова A. A. Bobryshev D. Yu. Vovk I. A. Luev N. R. Abidova R. S. Zhikhorev T. A. Zhelezkova Tigran Grigoryan T. A. Makarkina V. A. Ekimov A. V. Zhizhina Е. В. Карабина Olesya A. Kuchevskaya V. M. Filippova T. A. Linchenko A. A. Lisaeva Antonina N. Fedorova K. S. Maystrenko E. V. Markizova E. V. Kogay E. P. Krasnorutskaya М. Э. Попова Yu. Yu. Pchelin R. A. Ryanzhina D. B. Sidorov E. B. Shakhnovich С. М. Алексеев Maksim V. Zinkevich I. O. Belogortsev В. А. Чубенко V. M. Moiseenko N. Kh. Abduloeva A. A. Lebedinets L. V. Strakh L. K. Semenov M. B. Bolieva F. Z. Aydaeva

Aim . To assess the efficacy and safety of lenvatinib pembrolizumab for treatment mismatch repair-proficient endometrial cancer (EC) in routine clinical practice Russia. Materials methods This multicenter, retrospective, cohort study included patients with recurrent metastatic EC from 37 centers Russia treated between May 2020 April 2023. Patients histologically verified without microsatellite instability who received ≥1 course pembrolizumab/lenvatinib therapy were study. The primary...

10.17650/1994-4098-2023-19-4-104-113 article EN cc-by Tumors of female reproductive system 2024-01-20
 The long-term clinical efficacy and safety of lenvatinib plus pembrolizumab in endometrial cancer: data from routine clinical practice in Russia
OPENALEX - Publications 
А. Э. Протасова A. А. Rumyantsev M. Sheremet А. Yu. Goryainova M. V. Volkonsky and 54 more А. Г. Кедрова S. V. Kuzmicheva O. N. Aymamedova Х. С. Мусаева Svetlana Soroka Olha Romanchuk V. N. Orlova N. G. Graft Mavluda Ibragimova Yu. I. Merzlikina L. V. Stepura L. B. Tatulova A. A. Abasova A. A. Akopyan E. V. Arsenyeva Yu. V. Vasilyeva А. В. Белоногов Л. В. Криволапова A. A. Bobryshev D. Yu. Vovk I. A. Luev N. R. Abidova R. S. Zhikhorev T. A. Zhelezkova Tigran Grigoryan T. A. Makarkina V. A. Ekimov A. V. Zhizhina Е. В. Карабина Olesya A. Kuchevskaya V. M. Filippova T. A. Linchenko A. A. Lisaeva Antonina N. Fedorova K. S. Maystrenko E. V. Markizova E. V. Kogay E. P. Krasnorutskaya М. Э. Попова Yu. Yu. Pchelin R. A. Ryanzhina D. B. Sidorov E. B. Shakhnovich С. М. Алексеев Maksim V. Zinkevich I. O. Belogortsev В. А. Чубенко Vladimir M. Moiseenko N. Kh. Abduloeva A. A. Lebedinets L. V. Strakh L. K. Semenov M. B. Bolieva F. Z. Aydaeva

Background. Endometrial cancer (EC) treatment outcomes need to be improved. Immunotargeted therapy lead long-term and delayed effects compared chemotherapy. Estimation of efficacy quality life are crucial when we talking about in whole. Aim. To evaluate the clinical lenvatinib plus pembrolizumab patients with EC. Materials methods . The study included 43 stages I-IV EC mismatch repair-proficient tumors duration more than 9 months. We evaluated median progression-free survival, objective...

10.17650/1994-4098-2024-20-3-69-77 article EN cc-by Tumors of female reproductive system 2024-11-08
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