A5072119723- Pancreatic function and diabetes
- Bacterial Genetics and Biotechnology
- Bacteriophages and microbial interactions
- Magnetic Properties of Alloys
- Diabetes Management and Research
- Magnetic properties of thin films
- Microbial bioremediation and biosurfactants
- Cannabis and Cannabinoid Research
- Organ Donation and Transplantation
- ZnO doping and properties
- Organ Transplantation Techniques and Outcomes
- Gas Sensing Nanomaterials and Sensors
- Diabetes and associated disorders
- Synthesis of heterocyclic compounds
- Rare-earth and actinide compounds
- Pharmaceutical and Antibiotic Environmental Impacts
- Copper-based nanomaterials and applications
- Synthesis and biological activity
- Congenital Anomalies and Fetal Surgery
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- Plant Stress Responses and Tolerance
- Silicon Effects in Agriculture
- Microbial metabolism and enzyme function
- Growth Hormone and Insulin-like Growth Factors
Tohoku University
2000-2024
The University of Texas Health Science Center at Houston
2023-2024
Takeda (Japan)
2019
University of Yamanashi
2019
Gunma University
2017
Iwate University
2014
Beth Israel Deaconess Medical Center
2004
Harvard University
2004
Mie University
2003
Nagasaki University
2000
Plasmid partitioning and bacterial conjugation are critical processes ensuring plasmid maintenance dissemination, respectively, within populations. Although traditionally regarded as distinct phenomena, these two increasingly recognized interconnected. While ensures inheritance during cell division, its potential influence on conjugative transfer remains poorly understood. A major impediment to understanding their interplay is that partition systems often essential for stability, making it...
Bacterial type IV secretion systems (T4SSs) are a versatile family of macromolecular translocators, collectively able to recruit diverse DNA and protein substrates deliver them wide range cell types. Presently, there is little understanding how T4SSs recognize substrate repertoires form productive contacts with specific target cells. Although composed number conserved subunits adopt certain structural features, they also display considerable compositional diversity. Here, we explored the...
The rapid emergence of drug-resistant bacteria and current low rate antibiotic discovery emphasize the urgent need for alternative antibacterial strategies. We engineered Escherichia coli to conjugatively transfer plasmids specific E. Pseudomonas aeruginosa recipient cells through surface display cognate nanobody/antigen (Nb/Ag) pairs. further mobilizable carry CRISPR/Cas9 systems (pCrispr) selective killing harboring target sequences. In assembled programmed delivery system (PDS),...
In order to find new antiasthematic and antithrombotic agents, various [[1-aryl(or benzyl)-1-(benzenesulfonamido)methyl]phenyl]alkanoic acids derivatives were synthesized. Evaluation of these compounds for thromboxane A2 (TXA2) antagonistic activities indicated that 4-[4-[(4-chlorobenzenesulfonamido)phenylmethyl]phenyl]butyric acid (6h), 4-[4-[1-(4-chlorobenzenesulfonamido)-2-phenylethyl]butyric (6y) many other have potent inhibitory effects on U-46619-induced guinea-pig platelet...
Mouthguards (MGs) made from poly(ethylene-co-vinyl acetate) (EVA) are widely used in contact sports to prevent injuries such as breaking teeth and lip lacerations reduce brain concussion. However, the changes morphology molecular mobility of EVA, which can affect its physical properties during practical usage, have not been precisely examined. Therefore, we attempted determine main factors lead MG performance after one season use by high school rugby players. Solid-state nuclear magnetic...
Exposure to N2O5 generated by plasma technology activates immunity in Arabidopsis through tryptophan metabolites. However, little is known about the effects of exposure on other plant species. Sweet basil synthesizes many valuable secondary metabolites its leaves. Therefore, metabolomic analyses were performed at three different levels [9.7 (Ex1), 19.4 (Ex2) and 29.1 (Ex3) μmol] assess As a result, cinnamaldehyde phenolic acids increased with increasing doses. Certain flavonoids,...
ABSTRACT The thiol‐ene reaction between trans ‐limonene oxide ( ‐LO) and ethane‐1,2‐dithiol in the presence of triethylborane affords a bio‐based bis‐functional epoxide (bis‐ ‐LO). crosslinking bis‐ ‐LO with branched polyethyleneimine (BPEI; M n = 600; BPEI 600 ) at feed ratio ‐LO/BPEI 57/43 (wt/wt) yields corresponding network polymer T d10 (10% thermal decomposition temperature) 304.7 °C 98% yield. In contrast, negligible amounts are obtained by bis‐LO (bis‐functional derived from cis...
A phenanthrene degrader, Mycobacterium sp. EPa45, was isolated from a phenanthrene-degrading consortium. Here, we report the complete genome sequence of which has 6.2-Mb single circular chromosome. We propose degradation pathway in EPa45 based on sequence.
The phenanthrene-degrading Burkholderia sp. HB-1 was isolated from a phenanthrene-enrichment culture seeded with pristine farm soil sample. We report the complete genome sequence of HB-1, which has been deposited to stock (NBRC 110738) at Biological Resource Center, National Institute Technology and Evaluation (NITE), Tokyo, Japan. strain comprises two circular chromosomes 4.1 Mb 3.1 Mb. finishing facilitated by computational tools GenoFinisher, AceFileViewer, ShortReadManager.
In natural environments contaminated by recalcitrant organic pollutants, efficient biodegradation of such pollutants has been suggested to occur through the cooperation different bacterial species. A phenanthrene-degrading consortium, MixEPa4, from polluted soil was previously shown include a strain, Mycobacterium sp. EPa45, and non-polycyclic aromatic hydrocarbon (PAH)-degrading Burkholderia Bcrs1W. this study, we show that addition phenanthrene rich liquid medium resulted in transient...
In order to find new antiasthmatic agents with dual antagonistic activity against thromboxane A2 (TXA2) and leukotriene D4 (LTD4) receptors, synthesis pharmacological evaluation of various [4-[1-(benzenesulfonamido)-alkyl]phenyl]alkanoic acid derivatives were undertaken. TXA2 LTD4 activities in vitro evaluated by measuring the inhibitory effects on L-46619-induced contraction guinea-pig trachea LTD4-induced ileum trachea. Several compounds showed satisfactory activities, their effect (after...