A5102791116- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Airway Management and Intubation Techniques
- Pharmaceutical studies and practices
- Safe Handling of Antineoplastic Drugs
- Cancer therapeutics and mechanisms
- Streptococcal Infections and Treatments
- Therapeutic Uses of Natural Elements
- Advanced Breast Cancer Therapies
- Chronic Lymphocytic Leukemia Research
- Synthesis and Biological Activity
- Essential Oils and Antimicrobial Activity
- Surgical site infection prevention
- Magnesium in Health and Disease
- Tracheal and airway disorders
- Colorectal Cancer Treatments and Studies
- Synthesis and biological activity
- Reproductive tract infections research
- Restless Legs Syndrome Research
- Foreign Body Medical Cases
- Respiratory Support and Mechanisms
Hospital Clínico Universitario de Valencia
2024
PharmaMar (Spain)
2024
Universidad de Zaragoza
2023
Hospital General Universitario de Albacete
2019
Hospital Universitario Virgen Macarena
2014-2016
Antimicrobial resistance is a worldwide problem that urges novel alternatives to treat infections. In attempts find molecules, we assess the antimicrobial potential of seven essential oils (EO) different plants (Pinus sylvestris, Citrus limon, Origanum vulgare, Cymbopogon martini, Cinnamomum cassia, Melaleuca alternifolia and Eucalyptus globulus) against two multidrug-resistant bacteria species, i.e. Neisseria gonorrhoeae Streptococcus suis. EOs P. sylvestris C. limon revealed higher...
This open-label, two-part, phase Ib drug–drug interaction study investigated whether the pharmacokinetic (PK) and safety profiles of lurbinectedin (LRB), a marine-derived drug, are affected by co-administration itraconazole (ITZ), strong CYP3A4 inhibitor, in adult patients with advanced solid tumors. In Part A, three were sequentially assigned to Sequence 1 (LRB 0.8 mg/m2, 1-h intravenous [IV] + ITZ 200 mg/day oral Cycle [C1] LRB alone 3.2 h, IV 2 [C2]). B, 11 randomized (1:1) receive either...
Introduction Compared with the operating room, tracheal intubations in intensive care unit (ICU) are associated worsened glottic view, decreased first-time success rate and increase technical difficulty of intubation incidence complications. Videolaryngoscopes (VLs) have been proposed to improve airway management, while recent studies confirmed that VLs conditions this patient population, there remains a lack clarity regarding selection between standard Macintosh blade or hyperangulated one,...
<h3>Background</h3> Erlotinib, gefitinib and crizotinib are tyrosine kinase inhibitors (TKIs) used in the treatment of non-small cell lung cancer (NSCLC). Their hepatic metabolism involves several cytochrome p450 isoenzymes, making them susceptible to potential interactions. <h3>Purpose</h3> To identify analyse interactions between TKI patients’ home treatment, determine degree acceptance recommendations by clinician. <h3>Materials methods</h3> In our prospective study, we selected all...
<h3>Background</h3> Benzodiazepines (BZD) have to be reconciled within 24 h of admission avoid withdrawal symptoms. On the other hand, it's important check discharge report treatment discrepancies. <h3>Purpose</h3> To find out accuracy BZD reconciliation at and in our hospital. <h3>Material methods</h3> Observational prospective study carried a tertiary care hospital over two months. Patients 65 years without relevant psychiatric condition were selected. The prescribed was compared with...
<h3>Background</h3> Oral chemotherapy is increasingly used in Oncology. It has important advantages, such as patient comfort, but it also brings new challenges which did not exist with the intravenous treatment. Some of these drugs have interactions food, leading to changes their bioavailability. As they are a narrow therapeutic margin, this can lead alterations efficacy and/or toxicity. <h3>Purpose</h3> A. To assess level knowledge on administration oral cytostatics that present...