A5021472782- Transcranial Magnetic Stimulation Studies
- Traumatic Brain Injury Research
- Muscle activation and electromyography studies
- Cannabis and Cannabinoid Research
- Pancreatic function and diabetes
- Herpesvirus Infections and Treatments
- Congenital heart defects research
- Diet, Metabolism, and Disease
- Neuroscience and Neuropharmacology Research
- Metabolism and Genetic Disorders
- Prion Diseases and Protein Misfolding
- Mitochondrial Function and Pathology
- Neurological diseases and metabolism
- Poxvirus research and outbreaks
- Psychosomatic Disorders and Their Treatments
- Enzyme Structure and Function
- Children's Physical and Motor Development
- Epilepsy research and treatment
- Rabies epidemiology and control
- Conducting polymers and applications
- Lipid Membrane Structure and Behavior
- Thyroid Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
University of Alberta
2024
University of Saskatchewan
2019-2023
Czech Academy of Sciences, Institute of Physiology
2021
Monkeypox virus (MPXV) infections in humans cause neurological disorders while studies of MPXV-infected animals indicate that the penetrates brain. Pyroptosis is an inflammatory type regulated cell death, resulting from plasma membrane rupture (PMR) due to oligomerization cleaved gasdermins pore formation. Herein, we investigated human neural tropism MPXV compared another orthopoxvirus, vaccinia (VACV), as well its effects on immune responses and death. Astrocytes were most permissive (and...
Traumatic brain injury (TBI)/concussion is a growing epidemic throughout the world. Memory and neurobehavioral dysfunctions are among sequelae of TBI. Dislodgement cellular prion protein (PrPc) disruption circadian rhythm have been linked to Low-field magnetic stimulation (LFMS) new noninvasive repetitive transcranial (rTMS) technique that generates diffused low-intensity deep cortical subcortical areas. The role LFMS on PrPc, proteins related rhythm, behavior alterations in repeated TBI...
Brain injury/concussion is a growing epidemic throughout the world. Although evidence supports association between traumatic brain injury (TBI) and disturbance in glucose metabolism, underlying molecular mechanisms are not well established. Previously, we reported release of cellular prion protein (PrPc) from to circulation following TBI. The PrPc level was also found be decreased insulin-resistant rat brains. In present study, investigated link insulin resistance single repeated mild...
The type 1 and 2 cannabinoid receptors (CB1 CB2 receptors) are class A G protein-coupled (GPCRs) that activated by endogenous lipids called endocannabinoids to modulate neuronal excitability synaptic transmission in neurons throughout the central nervous system (CNS), inflammatory processes body. CB1 receptor is one of most abundant GPCRs CNS involved many physiological pathophysiological processes, including mood, appetite, nociception. primarily found on immunomodulatory cells both...
Recent studies show that repetitive transcranial magnetic stimulation (rTMS) improves cognitive and motor functions in patients with Parkinson's Disease (PD). Gamma rhythm low-field (LFMS) is a new non-invasive rTMS technique generates diffused low-intensity to the deep cortical subcortical areas. To investigate potential therapeutic effects of LFMS PD, we subjected an experimental mouse model (as early treatment). We examined effect on as well neuronal glial activities...
Recent studies show that repetitive transcranial magnetic stimulation (rTMS) improves cognitive and motor functions in patients with Parkinson’s Disease (PD). Gamma rhythm low-field (LFMS) is a new non-invasive rTMS technique generates diffused low-intensity to deep cortical subcortical areas. To investigate potential therapeutic effects of LFMS PD, we subjected an experimental mouse model (as early treatment). We examined the effect on as well neuronal glial activities...