A5008407169- Environmental Toxicology and Ecotoxicology
- Mercury impact and mitigation studies
- Toxic Organic Pollutants Impact
- Atomic and Molecular Physics
- HIV/AIDS drug development and treatment
- Supramolecular Chemistry and Complexes
- Laser Design and Applications
- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Hepatitis C virus research
- Heavy metals in environment
- Catalytic Cross-Coupling Reactions
- Molecular Sensors and Ion Detection
- Laser-induced spectroscopy and plasma
- Environmental Chemistry and Analysis
- X-ray Diffraction in Crystallography
- Pneumocystis jirovecii pneumonia detection and treatment
- Laser-Plasma Interactions and Diagnostics
- Oil Spill Detection and Mitigation
- Crystallization and Solubility Studies
- Marine Bivalve and Aquaculture Studies
- Catalytic C–H Functionalization Methods
- Microplastics and Plastic Pollution
- Catalytic Alkyne Reactions
- Poxvirus research and outbreaks
Autonomous University of Yucatán
2025
Institute for Social Security and Services for State Workers
2025
Universidad de Santiago de Chile
2024
Centre National de la Recherche Scientifique
2021
Université Toulouse III - Paul Sabatier
2021
Hospital Universitario La Paz
2001-2020
Hospital Son Llatzer
2012-2019
Polytechnic José Antonio Echeverría
1979-2018
Instituto Español de Oceanografía
2002-2011
Instituto Español de Estudios Estratégicos
2011
A number of calix[6]arenes bearing ureas at the upper rim positions alternate rings 1, 3 and 5 were prepared studied in detail by NMR spectroscopy gel permeation chromatography. N-Unsubstituted shown to dimerize through a cyclic array hydrogen bonds give cylindrical cavities capable encapsulating small molecules such as dichloromethane, benzene fluorobenzene. Slow equilibria between dimer monomer observed [D6]DMSO-CDCl3 mixtures. By contrast, N-substituted are monomeric. All urea monomers...
The intramolecular palladium-catalyzed reaction of aryl bromides and triflates with arenes has been used for the preparation polyarenes. synthesis benz[e]acephenantrylenes, corannulenes, C60H30, a 'crushed fullerene', by using this methodology are presented. Mechanistic studies on arylation step point to an electrophilic substitution pathway.
The palladium-catalyzed intramolecular arylation reaction has been applied to the synthesis of spiro polycyclic aromatic hydrocarbons and planar by formation a six-membered ring. proceeds more readily with aryl bromides substituted electron-withdrawing groups using palladium acetate in N,N-dimethylformamide as solvent. For less reactive p-methoxyaryl derivatives use LiI an additive was shown give best results. results obtained cyclization nitro 21 23 suggest that second step is not...
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of lymphomas. The current classification recognizes an expanding distinct entities, with this being the most common. Up to one-third DLBCL cases may originate in nearly any organ, commonly gastrointestinal tract, skin and soft tissues, bones, or genitourinary tract. A 52-year-old woman no history chronic degenerative diseases presented severe abdominal pain, weight loss, night sweats. As part her evaluation, abdominopelvic CT...
A number of calix[6]arenes bearing ureas at the upper rim positions alternate rings 1, 3 and 5 were prepared studied in detail by NMR spectroscopy gel permeation chromatography. N-Unsubstituted shown to dimerize through a cyclic array hydrogen bonds give cylindrical cavities capable encapsulating small molecules such as dichloromethane, benzene fluorobenzene. Slow equilibria between dimer monomer observed [D6]DMSO-CDCl3 mixtures. By contrast, N-substituted are monomeric. All urea monomers...
The preorganization of bifunctional 2-ureido-4-pyrimidinones mediated by either 1,3-substituted adamantane or meta-substituted phenylene ring linkers leads to the preferred formation stable pentameric (1)(5) and hexameric (2)(6) assemblies, respectively. Despite high binding constant 2-ureido-4-pyrimidinone dimers highly preorganized structure monomer, predominant cycles in solution occurs only within a specific concentration range.
A C60-dimer connected through a highly directional fourfold hydrogen bonding motif has been synthesized; photophysical measurements reveal strong electronic coupling the bond edge.
In the ART-PRO pilot trial there were no virological failures through 48 weeks of treatment with dolutegravir plus lamivudine in suppressed individuals and without archived resistance-associated mutations (RAMs) detected next-generation sequencing (NGS) but evidence RAMs baseline proviral DNA population sequencing.To present 96 week results from ART-PRO.Open-label, single-arm trial. At baseline, all participants switched to lamivudine. Participants excluded if genotyping RAMs. To detect...
Tightly linked! A linear array of complementary hydrogen bonds forms between two 2-ureidopyrimidin-4(1H)-one rings attached to the upper rims facing 1,3-alternate calix[4]arenes (shown schematically). The strength binding (Kass >106 M-1 in chloroform) and efficiency self-assembly open up interesting perspectives design highly ordered multicomponent cages.
Abstract Three ammonium halide type surfactants were tested under standard laboratory condition for biodegradability and acute toxicity to Daphnia magna in the Microtox test with luminescent bacterium Photobacterium phosphoreum. The compounds are dimethyldistearylammonium chloride (DSDMAC), cetyltrimethylammonium bromide (HTMAB) cetylbenzyldimethylammonium (HBDMAC). results indicate DSDMAC is less toxic than other two that it biodegrades rapidly at both lower (2.5 mg/L) higher (10 concentrations.