A5089982669- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Appendicitis Diagnosis and Management
- Advanced MRI Techniques and Applications
- Diverticular Disease and Complications
- Ultrasound in Clinical Applications
- Atrial Fibrillation Management and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Radiation Dose and Imaging
- Infective Endocarditis Diagnosis and Management
- Acute Ischemic Stroke Management
- Sports injuries and prevention
- Cerebrovascular and Carotid Artery Diseases
- Cardiac tumors and thrombi
- Cardiovascular and Diving-Related Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Microbial Inactivation Methods
- Gastrointestinal disorders and treatments
- Cardiac Valve Diseases and Treatments
- Cardiomyopathy and Myosin Studies
- Emergency and Acute Care Studies
- Meta-analysis and systematic reviews
- Traumatic Brain Injury and Neurovascular Disturbances
- Colorectal Cancer Screening and Detection
- Advanced X-ray and CT Imaging
Amsterdam University Medical Centers
2020-2025
University of Amsterdam
2008-2024
Amsterdam UMC Location University of Amsterdam
2007-2024
Amsterdam University of Applied Sciences
2024
St. Antonius Ziekenhuis
2009
OLVG
2009
Gelre Hospitals
2009
To identify an optimal imaging strategy for the accurate detection of urgent conditions in patients with acute abdominal pain.Fully paired multicentre diagnostic accuracy study prospective data collection.Emergency departments two university hospitals and four large teaching Netherlands.1021 non-traumatic pain >2 hours' <5 days' duration. Exclusion criteria were discharge from emergency department no considered warranted by treating physician, pregnancy, haemorrhagic shock.All had plain...
Head-to-head comparison of ultrasound and CT accuracy in common diagnoses causing acute abdominal pain.Consecutive patients with pain for >2 h <5 days referred imaging underwent both US by different radiologists/radiological residents. An expert panel assigned a final diagnosis. Ultrasound sensitivity predictive values were calculated frequent diagnoses. Effect patient characteristics observer experience on was studied.Frequent the 1,021 (mean age 47; 55% female) appendicitis (284; 28%),...
PURPOSE: The aim of this study was to identify patients in whom the clinical diagnosis diverticulitis can be made with a high certainty, distinguishing them from requiring imaging. METHODS: We prospectively recorded features acute abdominal pain presenting at emergency department, before they underwent identified significantly associated final using multivariate logistic regression analysis and developed decision rule based on these features. evaluated performance identifying probability...
Irreversible electroporation (IRE) is an ablative therapy with a low side-effect profile in prostate cancer. The objective was: 1) To compare the volumetric IRE ablation zone on grey-scale transrectal ultrasound (TRUS), contrast-enhanced (CEUS) and multiparametric MRI (mpMRI) histopathology findings; 2) determine reliable imaging modality to visualize effects accurately. A prospective phase I-II study was performed 16 patients scheduled for radical prostatectomy (RP). of 4 weeks before RP....
<h3>Background and Objectives</h3> Guidelines recommend echocardiography to screen for structural sources of cardioembolism in patients with ischemic stroke. Cardiac CT is a promising alternative as first-line screening method. We aimed determine whether cardiac CT, acquired during the initial stroke imaging protocol, has higher yield detecting high-risk cardioaortic embolism than transthoracic (TTE). <h3>Methods</h3> performed prospective, single-center, observational cohort study included...
To compare the diagnostic accuracy of conditional computed tomography (CT), i.e. CT when initial ultrasound findings are negative or inconclusive, and immediate for patients with suspected appendicitis. Data were collected within a prospective study on imaging in adults acute abdominal pain. All underwent CT, read by different observers who blinded from other modality. Only clinical suspicion appendicitis included. An expert panel assigned final diagnosis to each patient after 6 months...
Left atrial appendage (LAA) slow-flow may increase the risk of ischemic stroke. We studied LAA attenuation on cardiac computed tomography in patients with acute
Abstract Aims Limited data indicates that athletes’ hearts demonstrate decreased native T1, but this assertion has not been replicated in large cohorts of extreme phenotypes elite athletes. Therefore, we investigated differences T1 between athletes and healthy non-athletic controls. Methods Results Cross-sectional analysis comparing (≥ 16 years; ≥ 10 hours exercise/week) age-matched All participants underwent cardiovascular magnetic resonance imaging on a 1.5 tesla MRI machine. We included...
To identify and evaluate profiles of US CT features associated with acute appendicitis.Consecutive patients presenting abdominal pain at the emergency department were invited to participate in this study. All underwent CT. Imaging known be appendicitis, an imaging diagnosis prospectively recorded by two independent radiologists. A final was assigned after 6 months. Associations between appendiceal a appendicitis evaluated logistic regression analysis.Appendicitis 284 942 (30%). appendicitis....
The purpose was to evaluate low-dose CT colonography without cathartic cleansing in terms of image quality, polyp visualization and patient acceptance. Sixty-one patients scheduled for colonoscopy started a low-fiber diet, lactulose amidotrizoic-acid fecal tagging 2 days prior the scan (standard dose, 5.8-8.2 mSv). original raw data 51 were modified reconstructed at simulated 2.3 0.7 mSv levels. Two observers evaluated standard dose regarding quality polyps. A third presence polyps all three...
The acute abdomen is a frequent entity at the Emergency Department (ED), which usually needs rapid and accurate diagnostic work-up. Diagnostic work-up with imaging can consist of plain X-ray, ultrasonography (US), computed tomography (CT) even laparoscopy. However, no evidence-based guidelines exist in current literature. actual patient abdominal pain presenting to ED varies greatly between hospitals physicians. OPTIMA study was designed provide evidence base for constructing an optimal...
To prospectively evaluate the diagnostic performance of magnetic resonance (MR) colonography by using limited bowel preparation in patients with polyps 10 mm or larger diameter a population at increased risk for colorectal cancer, optical colonoscopy as reference standard.The institutional review boards all three hospitals approved study. All provided written informed consent. In this multicenter study, undergoing because personal family history cancer adenomatous were included. Two blinded...
The objective was to evaluate the diagnostic accuracy of clinical features and laboratory test results in detecting acute appendicitis.Clinical were prospectively recorded a consecutive series 1,101 patients presenting with abdominal pain at emergency department (ED) six hospitals. Likelihood ratios (LRs) areas under receiver operating characteristic curve (AUC) calculated for individual features. Variants presentation, based on different combinations features, investigated accuracies...
The level of inter-observer agreement abdominal computed tomography (CT) in unselected patients presenting with acute pain at the Emergency Department (ED) was evaluated. Two hundred consecutive were prospectively included. Multi-slice CT performed all intravenous contrast medium only. Three radiologists independently read examinations. They recorded specific radiological features and a final diagnosis on case record form. We calculated proportion kappa values, for overall, urgent frequently...
Computed tomography angiography (CTA) is performed routinely in the work-up for transcatheter aortic valve implantation (TAVI), and could potentially replace invasive coronary (ICA) to rule out left main (LM) proximal stenosis. The objectives were assess diagnostic yield accuracy of pre-TAVI CTA detect LM stenosis ≥ 50% 70% diameter (DS).The DEPICT database consists individual patient data from four studies with a retrospective design that analyzed stenosis, as compared ICA. Pooled used...
Cardiac thrombi are a major risk factor for ischemic stroke, but rarely diagnosed in the acute phase. We examined characteristics and functional outcome of patients with stroke concomitant cardiac thrombus detected on CT performed phase.We used data from "Mind Heart," prospective cohort study which consecutive adult underwent ECG-gated during their imaging protocol. compared characteristics, (modified Rankin scale) recurrence rate at 90 days (defined as filling defect <100 Hounsfield Units)...
Cardiac computed tomography (CT) acquired during the initial acute stroke imaging protocol (acute cardiac CT) is increasingly used to screen for cardioembolism, but information on long-term clinical implications of its findings lacking.
In patients with clinically suspected appendicitis, imaging is needed to substantiate the clinical diagnosis. Imaging accuracy of ultrasonography (US) suboptimal, while most accurate technique (CT) associated cancer related deaths through exposure ionizing radiation. MRI a potential replacement, without radiation and no need for contrast medium administration. If proven be sufficiently accurate, it could introduced in diagnostic pathway increasing improving outcomes, risk induced or...
Combining reirradiation (reRT) and hyperthermia (HT) has shown high therapeutic value for patients with locoregional recurrent breast cancer (LR). However, additional toxicity of (e.g., rib fractures) may occur. The aim this study is to determine the impact potential risk factors on occurrence fractures.From 1982-2005, 234 were treated adjuvant reRT + HT after surgery LR. ReRT consisted typically 8 fractions 4 Gy twice a week, or 12 3 four times week. A total 118 irradiated abutted photon...
Abstract Background To retrospectively assess the added value of an artificial intelligence (AI) algorithm for detecting pulmonary nodules on ultra-low-dose computed tomography (ULDCT) performed at emergency department (ED). Methods In OPTIMACT trial, 870 patients with suspected nontraumatic disease underwent ULDCT. The ED radiologist prospectively read examinations and reported incidental requiring follow-up. All ULDCTs were processed post hoc using AI deep learning software marking ≥ 6 mm....
Abstract Patients clinically suspected of community-acquired pneumonia (CAP) were randomized between ultralow-dose chest computed tomography ([ULDCT] 261 patients) and radiograph ([CXR] 231 patients). We did not find evidence that performing ULDCT instead CXR affects antibiotic treatment policy or patient outcomes. However, in a subgroup afebrile patients, there more patients diagnosed with CAP the group (ULDCT, 106 608 patients; CXR, 71 654 P = .001).