- Herpesvirus Infections and Treatments
- Ovarian cancer diagnosis and treatment
- Cytomegalovirus and herpesvirus research
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Endometriosis Research and Treatment
- Cancer-related molecular mechanisms research
- Viral-associated cancers and disorders
- Reproductive System and Pregnancy
- Ferroptosis and cancer prognosis
- Testicular diseases and treatments
- Cancer, Lipids, and Metabolism
- Neuroendocrine Tumor Research Advances
- RNA modifications and cancer
- Immune Cell Function and Interaction
- Hematological disorders and diagnostics
- Uterine Myomas and Treatments
- Cancer Immunotherapy and Biomarkers
- IgG4-Related and Inflammatory Diseases
- Immunotherapy and Immune Responses
- RNA regulation and disease
- Molecular Biology Techniques and Applications
- Urinary and Genital Oncology Studies
- Renal and related cancers
- Cancer Diagnosis and Treatment
Beijing Obstetrics and Gynecology Hospital
2023-2025
Capital Medical University
2023-2025
Weifang Medical University
2023
Weatherford College
2023
Dalian University of Technology
2022
Qingdao University
2020-2021
Affiliated Hospital of Qingdao University
2021
Despite advances in various chemotherapy regimens, current therapeutic options are limited for ovarian cancer patients. Oxidative stress-induced growth inhibitor 1 (OSGIN1), which is a tumor suppressor gene known to regulate the cellular stress response and apoptosis, associated with development. However, underlying mechanisms involved ferroptosis regulation have not been elucidated. Thus, this study aimed investigate effect regulatory mechanism of OSGIN1 on cells. Our results demonstrated...
Ovarian cancer, one of the deadliest malignancies, lacks effective treatment, despite advancements in surgical techniques and chemotherapy. Thus, new therapeutic approaches are imperative to improving treatment outcomes. Immunotherapy, which has demonstrated considerable success managing various cancers, already found its place clinical practice. This review aims provide an overview ovarian tumor immunotherapy, including basics, key strategies, research data supporting potential. In...
Endometriosis (EMs) is a prevalent gynecological disorder characterized by the growth of uterine tissue outside cavity, causing debilitating symptoms and infertility. Despite its prevalence, exact mechanisms behind EMs development remain incompletely understood. This article presents comprehensive overview relationship between gut microbiota imbalance pathogenesis. Recent research indicates that plays pivotal role in various aspects EMs, including immune regulation, generation inflammatory...
Fallopian tube carcinoma has a rare incidence and dismal prognosis. Sister Mary Joseph’s nodule is an intra-abdominal tumor that metastasizes to the umbilicus. To date, fewer than 10 cases of fallopian with have been reported, most them exhibiting very poor Herein, we described case nodule. A 57-year-old woman was referred Affiliated Hospital Shandong Second Medical University in May 2020 owing mass middle her She first diagnosed umbilical underwent resection mass, which revealed...
Background and Aims The association of the triglyceride-glucose (TyG) index, a promising novel biomarker for insulin resistance, with risk endometriosis has not been investigated to date. This nationwide study aimed explore between TyG index risk. Methods Data were obtained from National Health Nutrition Examination Survey (1999–2006). Female participants who provided complete data on enrolled in analysis. Multivariate logistic regression analyses utilized assess endometriosis, adjusted by...
To investigate the association of primary tumor site with prognosis in vulvar cancer, stratified by squamous cell carcinoma (SCC) and non-SCC histological types.
Abstract Background The cause of epithelial ovarian cancer (EOC) is not elucidated. Viral infection may induce chronic inflammatory and play a role in the pathogenesis cancers. Some viruses are considered to be oncomodulatory, modulating cellular pathways such as cell proliferation, tumor progression, vascular disease development, immune evasion. Human cytomegalovirus (HCMV) has been detected several types cancers including cancer. However, HCMV carcinogenesis remains controversial....
Rationale: Malignant transformation of mature cystic teratoma is very rare, which squamous cell carcinoma (SCC) the most common type. Prognosis SCC arising in ovary poor. Our experience may provide new ideas for treatment this disease. Patient concerns: The patient was a 56-year-old woman and admitted lower abdominal pain. She underwent laparoscopic surgery with 4 cycles chemotherapy had achieved complete response; 10 months after completion initial treatment, her cancer relapsed....
Abstract Background: The cause of epithelial ovarian cancer(EOC) is not elucidated. Viral infection may induce chronic inflammatory and play a role in the pathogenesis cancers. Some viruses are considered to be oncomodulatory, modulating cellular pathways such as cell proliferation, tumor progression, vascular disease development, immune evasion. Human cytomegalovirus (HCMV) has been detected several types cancers including cancer. However, HCMV carcinogenesis remains controversial....
Abstract Background: The cause of epithelial ovarian cancer(EOC) is not elucidated. Viral infection may induce chronic inflammatory and play a role in the pathogenesis cancers. Some viruses are considered to be oncomodulatory, modulating cellular pathways such as cell proliferation, tumor progression, vascular disease development, immune evasion. Human cytomegalovirus (HCMV) has been detected several types cancers including cancer. However, HCMV carcinogenesis remains...
Abstract Background: The cause of epithelial ovarian cancer(EOC) is not elucidated. It has been proved that infectious agents could contribute to carcinogenesis. Human cytomegalovirus (HCMV) detected in several types tumors. Objective: To investigate the potential role HCMV infection EOC, we evaluated prevalence proteins EOC tissue sections and its impacts on patients’ survival. Methods: Formalin-fixed, paraffin-embedded tissues from 66 patients with 30 benign cystadenoma were studied....