A5030612481- Pancreatic and Hepatic Oncology Research
- Cancer Treatment and Pharmacology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiopharmaceutical Chemistry and Applications
- MicroRNA in disease regulation
- Estrogen and related hormone effects
- Multilevel Inverters and Converters
- HER2/EGFR in Cancer Research
- Microgrid Control and Optimization
- Pancreatitis Pathology and Treatment
- Cancer-related molecular mechanisms research
- Neuroendocrine Tumor Research Advances
- Advanced Breast Cancer Therapies
- Advanced DC-DC Converters
- Neuroblastoma Research and Treatments
- Circular RNAs in diseases
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
Chinese PLA General Hospital
2024
Inner Mongolia University of Technology
2023
Hebei Medical University
2020
Second Hospital of Hebei Medical University
2020
Abstract Triple-negative breast cancer (TNBC) cells are in a more hypoxic and starved state than non-TNBC cells, which makes TNBC always maintain high autophagy levels. Emerging evidence has demonstrated that circular RNAs (circRNAs) involved the progress of tumorigenesis. However, regulation functions autophagy-induced circRNAs remain unclear. In our study, autophagy-responsive circRNA candidates under amino acid were identified by RNA sequencing. The results showed circEGFR expression was...
Abstract Background: Patients (pts) with mTNBC have limited treatment options and poor prognosis. The estimated median overall survival (OS) of pts is 12 to 18 months (mo) after diagnosis. SKB264, an antibody drug conjugate (ADC) composed anti-TROP2 coupled a cytotoxic belotecan-derivative via novel linker average Drug Antibody Ratio (DAR) 7.4, has shown promising anti-tumor activity tolerable safety profile in (Yin, Y. et al. SABCS 2022). Here, we report the updated data from Phase 2...
Abstract Background Breast cancer is the most frequently diagnosed and 5th common cause of cancer-related death in Chinese women with over 416,000 new cases 117,000 deaths estimated 2020. Triple-negative breast (TNBC) represents 10%-20% cancer. Sacituzumab govitecan (SG) a Trop-2-directed antibody-drug conjugate approved for second-line or later (2L+) treatment metastatic (m)TNBC multiple countries, including US China. In pivotal phase 3 study ASCENT, which enrolled predominantly non-Asian...
Objective: To examine the effect of pancreaticojejunostomy with pancreatic duct binding external drainage in laparoscopic pancreatoduodenectomy. Methods: The data 21 patients who underwent pancreaticoduodenectomy same treatment group from January 2017 to October 2019 Department Hepatobiliary Surgery Second Hospital Hebei Medical University were analyzed retrospectively.All ducts.There 12 males and 9 females, aged (63.1±8.1)years old (range: 46 77 years old), body mass index...
When the grid voltage is unbalanced, typical PI controller's double closed-loop control method ineffective in suppressing current distortion on AC side and second harmonic wave of DC a three-phase rectifier type PWM. Based this, this research provides an enhancement predictive by three vectors model based traditional two model, which eliminates need for multiple loop regulators decoupling under positive negative sequence, By using basic each sector to synthesize six expected any amplitude...
Objective To summarize the technical points of laparoscopic pancreaticoduodenectomy (LPD) carried out in a single center. Methods The clinical data 102 patients who underwent 2018 at Department Hepatobiliary Surgery Second Hospital Hebei Medical University were retrospectively analyzed, and general conditions, operation time, intraoperative blood loss, surgical analyzed. Post-operative complications, hospital stay other indicators studied. Results Of included, there 57 males 45...
Abstract Background: There is no widely-accepted staging system for pancreatic neuroendocrine tumors (pNETs). The aim of this study was to validate the American Joint Committee on Cancer (AJCC) 8th edition well-differentiated (G1/G2) pNETs. Methods: A multicenter dataset (n=1086) used evaluate application AJCC 7 th and 8th, European Neuroendocrine Tumor Society (ENETS), modified ENETS (mENETS) systems Results: proportion patients with stage III extremely low (1.1%) according 7th system. For...