A5100713656- Prostate Cancer Treatment and Research
- Cancer Genomics and Diagnostics
- Coronary Interventions and Diagnostics
- Prostate Cancer Diagnosis and Treatment
- Cardiac Imaging and Diagnostics
- Genetic factors in colorectal cancer
- Acute Myocardial Infarction Research
- Cancer, Lipids, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Cerebrovascular and Carotid Artery Diseases
- Renal and Vascular Pathologies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Genetic Mapping and Diversity in Plants and Animals
- Cerebrospinal fluid and hydrocephalus
- Renal cell carcinoma treatment
- Genetic and phenotypic traits in livestock
- Educational Reforms and Innovations
- Traumatic Brain Injury and Neurovascular Disturbances
- Colorectal Cancer Surgical Treatments
- Liver Disease Diagnosis and Treatment
Nanjing Medical University
2023-2025
Soochow University
2012-2025
First Affiliated Hospital of Soochow University
2012-2025
Yancheng Third People's Hospital
2024-2025
Jiangsu Vocational College of Medicine
2025
Shanghai Tenth People's Hospital
2023-2024
Nantong University
2008-2024
Tianjin Medical University
2024
Yunnan University of Finance And Economics
2023-2024
Hebei Medical University
2017-2023
Globally, lung cancer represents the leading cause of cancer-related mortality, with 85% cases attributable to non-small cell (NSCLC). Metastatic progression remains a major challenge in treating advanced cancer, resulting dismal five-year survival rate 20-30%. Hyaluronan mediated motility receptor (HMMR) has been identified as novel oncogene NSCLC. However, its exact role and mechanisms NSCLC metastasis are yet be fully understood. Elevated mRNA protein levels HMMR were observed human...
Objective: We aimed to examine the effects of sleep quality on association between pre-bedtime electronic screen media use for entertainment and academic performance among college students. hypothesized that mediates Methods: This was a cross-sectional survey with 1385 participants (age 19.99 ± 1.4 years [range, 17– 24 years] 36.82% males) conducted at Shantou University. The levels were based self-reported class ranking from average grades their last final major examinations. Poor defined...
Abstract Pancreatic cancer has an extremely terrible prognosis and is a common cause of death. In this study, the clinic value, biological function underlying mechanisms Zinc finger protein 655 (ZNF655) in human pancreatic were evaluated. The expression level ZNF655 was determined by immunohistochemistry (IHC) staining. effects cells investigated loss/gain-of-function assays vitro vivo. downstream molecular mechanism explored using co-immunoprecipitation (Co-IP), dual-luciferase reporter...
Background Patients with end-stage renal disease have a high mortality from coronary artery disease, but the impact of moderate insufficiency on clinical outcomes after percutaneous intervention (PCI) and effect drug-eluting stent implantation in these patients remain unclear. This study determined long-term death major adverse cardiac events (MACE) based PCI examined whether could favourably influence outcome. Methods Major causes were for 1012 undergoing January 1, 2002 to December 31,...
The application of drug-eluting stent (DES), either sirolimus-eluting (Cypher, Cordis, USA) or paclitaxel-eluting (Taxus, Boston Scientific, USA), in treatment patients with coronary artery disease (CAD) has achieved great success.1-4 high cost imported DES (either Cypher Taxus) gave the birth to a China-made, polymer-based, (Firebird, Microport Company, China). In March 2003, China Food and Drug Administration approved clinical use Firebird stent. However, safety efficacy comparison Taxus...
Background Large animal models with toxin-mediated pancreatic damage have been used extensively in researches respect to diabetes mellitus and cardiovascular diabetic complications. The present study aimed establish Chinese Guizhou minipig streptozotocin (STZ)-induced characterize the by analyzing inflammatory cytokine levels aortic wall, such as tumor necrosis factor (TNF)-α, interleukin-1β (IL-1β) interleukin-6 (IL-6). Methods Twenty-two male minipigs (age, 4 6 months; weight, 20 kg 30 kg)...
ObjectivePrevious studies from outside China showed that the knowledge, attitudes, and practice (KAP) of chronic refractory cough (CRC) was moderate among physicians. This study examined KAP toward CRC in Chinese healthcare providers.MethodsThis single-center cross-sectional conducted at The Sixth Affiliated Hospital Nantong University, Yancheng Third People's Hospital, July 2022 to January 2023 enrolled providers. demographic characteristics scores were collected using a questionnaire...
Background Primary percutaneous coronary intervention (PCI) has been identified as the first therapeutic option for patients with acute ST-segment elevation myocardial infarction (STEMI). The strategy of transferring patient to a PCI center was recently recommended those STEMI who were present incapable hospitals, which include lack facilities or experienced operators. In China, some local hospitals have equipped facilities, but they no interventional physicians qualified performing primary...
Background The optimal reperfusion strategy in elderly patients with ST-elevation myocardial infarction (STEMI) remains unclear. purpose of this study was to evaluate the safety, in-hospital and one-year clinical outcomes for >75 years age STEMI receiving primary percutaneous coronary intervention (PCI), compared those treated by conservative approach. Methods One hundred two presented <12 hours were randomly allocated PCI (n=50) or therapy only (n=52). baseline characteristics, outcome...
Background Drug-eluting stent (DES) has been used widely for the treatment of patients with acute coronary syndrome or without diabetes mellitus during percutaneous intervention (PCI), but its long-term safety and efficacy in diabetic ST elevation myocardial infarction (STEMI) remain uncertain. This study aimed to investigate clinical outcomes after primary DES implantation STEMI, compared non-diabetic counterparts. Methods From December 2004 March 2006, 56 consecutive (diabetic group) 170...
Multiple randomized clinical trials have demonstrated that drug eluting stents can significantly reduce the rates of restenosis and subsequent adverse events across lesion patient. We investigated medium term efficacy safety Firebird sirolimus stent (SES) in coronary artery disease.The sample was 509 consecutive patients with disease (CAD) who were treated by SES finished three-year follow-up. The occurrences major cardiac (MACE) Academic Research Consortium defined thrombosis (ST) evaluated...
Background Transradial access has been increasingly used during primary percutaneous coronary intervention (PCI) for patients with acute ST-segment elevation myocardial infarction (STEMI) in last decade. Clinical benefits of upstream use tirfiban therapy STEMI treated by PCI have reported. We investigated the merits transradial vs. transfemoral tirofiban. Methods Patients tirofiban between December 2006 and October 2012 then were compared ( n =298) =314) access. Baseline demographics,...
Prognosis of patients with acute ST-elevation myocardial infarction (STEMI) and renal dysfunction (RD) who received primary percutaneous coronary intervention (PCI) has not been fully investigated in the drug-eluting stent (DES) era. This study aimed to evaluate impact admission serum creatinine level on short-term outcomes STEMI undergoing DES-based PCI.Primary PCI DES implantation was attempted 619 consecutive within 12 hours symptom onset. Among them, 86 had a > or = 115 micromol/L (RD...
Abstract To develop a predictive model and nomogram for predicting postoperative hemorrhage in preoperative patients undergoing laparoscopic pancreaticoduodenectomy (LPD). A total of 409 LPD that underwent by the same surgical team between January 2014 December 2020 were included as training cohort. The data statistically compared analyzed exploring factors correlated with hemorrhage. was developed multivariate logistic regression stepwise (stepAIC) selection. based on developed....
(1)H-magnetic resonance spectroscopy imaging and diffusion tensor were performed in 19 patients with mild depression 13 controls. The mean age of the was 31 years. Hamilton score 22.5 ± 13.2. N-acetylaspartate, choline creatine concentrations average coefficient fractional anisotropy values measured bilateral hippocampus, striatum, thalamus prefrontal deep white matter. Compared control group, depressed had: (1) a higher choline/creatine ratio negative correlation between hippocampus; (2)...
Sequencing of circulating tumor DNA (ctDNA) is a minimally invasive approach to reveal the genomic alterations cancer; however, its comparison with sequencing tissue has not been well documented in real-world patients aggressive-variant prostate cancer (AVPC). Concordance was assessed between progressive and matched ctDNA by next-generation for 63 AVPC. Associations progression-free survival (PFS) overall (OS) were investigated using Kaplan-Meier Cox regression analyses. A total 161 somatic...