Cystic echinococcosis is a worldwide chronic zoonotic disease that threatens human health and animal husbandry. Exosome-like vesicles (ELVs) have emerged recently as mediators in the parasite-parasite inter-communication parasite-host interactions. ELVs from parasites can transfer non-coding RNAs (ncRNAs) into host cells to regulate their gene expression; however, ncRNAs profiles of E. granulosus remain unknown. Here, we isolated protoscolece (PSC)-ELVs hydatid fluid (HF)-ELVs culture medium...

Clonorchiasis is an infectious disease caused by helminths of Clonorchis sinensis (C. sinensis). The adult parasite mainly inhabits the bile duct and gall bladder, results in various complications to hepatobiliary system. amount secreted into intestine reduced cases C. infection, which may alter pH gut decrease surfactant protein D released from gallbladder. However, impact parasitic infection on human microbiome remains unclear. To this end, we examined microbiota composition 47 modified...

Abstract To achieve sustainable development goals in Huangshui River Basin (HRB), strengthening adaptive water resources management under the dual impact of climate change (CC) and human interventions (HI) is great significance. Multiple mathematical statistical methods were employed to determine runoff trend breakpoint HRB. The elasticity CC HI on decline their contributions quantitatively discerned based Budyko hypothesis, complementary method, SWAT hydrological model. results show that...

Abstract Palaeoshorelines, highstand lacustrine sediments and lakeshore terraces are preserved around saline lakes in the arid Qaidam Basin. Previous research indicates that chronology of a mega‐paleolake Basin during late Pleisotocene is controversial. Here we report quartz optically stimulated luminescence (OSL) age estimates sediments, shoreline features geomorphic exposures contribute to revision lake level history Gahai Toson north‐eastern Basin, on northeastern Qinghai–Tibetan Plateau...

Cystic echinococcosis is a worldwide chronic zoonotic disease caused by infection with the larval stage of Echinococcus granulosus. Previously, we found significant accumulation myeloid-derived suppressor cells (MDSCs) in E. granulosus mouse models and that they play key role immunosuppressing T lymphocytes. Here, compared long non-coding RNA (lncRNA) mRNA expression patterns between splenic monocytic MDSCs (M-MDSCs) protoscoleces-infected mice normal using microarray analysis. LncRNA...

Cystic echinococcosis is a chronic disease caused by infection with the larvae of Echinococcus granulosus. The parasite's ability to establish persistent partly due its evolving immune evasion strategies. One strategy may involve protective effect arginase, which impedes control pathogens or tumors, whereas it remains largely unknown during E. granulosus infection. Here, we analyzed whether arginase was produced in peritoneal cells and assessed role immunosuppression mice infected...

Abstract Background Enterocytozoon bieneusi is the most frequently detected microsporidian species in humans and animals. Currently, to best of our knowledge, no information on E. infection Himalayan marmots ( Marmota himalayana ) Alashan ground squirrels Spermophilus alashanicus available worldwide. The aim present study was understand occurrence genetic characterizations Qinghai-Tibetan Plateau area (QTPA), Gansu Province, China. Methods A total 498 intestinal contents were collected from...

Ecosystem carbon dioxide (CO 2 ), water vapor, and heat exchanges in alpine wetlands on the Qinghai–Tibetan Plateau are not comprehensively understood. Thus, we studied variability of net ecosystem CO exchange (NEE), respiration (Re), gross primary production (GPP), evapotranspiration (ET), fluxes over a headwater wetland Qinghai Lake region. Results showed that was absorption annual scale, which monthly NEE, GPP, Re two consecutive years varied from −165.16 to 93 g m −2 mo −1 , 6.66 384.45...

Thermokarst lakes are formed as a result of thawing ice-rich permafrost, transforming vast permafrost soil into lake sediment and changing the biogeochemistry carbon (C), nitrogen (N), phosphorus (P). Degraded thermokarst two distinct fates pristine in processes. However, we do not clearly understand differences relationships between degraded from stoichiometric perspective. In this study, 44 across Qinghai-Tibet Plateau were investigated to collect surrounding soil. general, C, N, P...

The use of geostatistics to explore the spatial distribution and variability soil properties has become an important tool recognize properties. In this paper, we combined actual field sampling data with study characteristic organic matter carbon content around Qinghai Lake. results showed that mean is 5.95 ± 3.40%, 3.45 1.97%, both are low. variogram model semi-variance function graph models exponential model. Isotropic ratio nugget sill 82.9% 83%, variable range 9300m, all in range, here...

Evapotranspiration is an important process in the water budget of ecosystem. Quantifying components evapotranspiration great significance revealing ecohydrological alpine inland river basins. In this study, fluxes Shaliu River basin were classified by hydrogen and oxygen stable isotope technology remote sensing technology. The results showed following: (1) average value soil fractional evaporation (E1) summer 2018 2019 was 7.59 mm 2.10 mm, respectively. (2) ratio (Esoil) 48.82%, 68.11%,...

As the “Asian Water Tower”, understanding hydrological cycles in Qinghai Province and its interior is critical to security of terrestrial ecosystems. Based on Moderate Resolution Imaging Spectroradiometer (MODIS)16 evapotranspiration (ET) remote sensing data, we used least squares regression, correlation analysis, t-test determine temporal spatial changes trends ET five ecological functional regions, located Qinghai–Tibet Plateau (Plateau) Western China from 2000 2020. In addition, discussed...

To evaluate the soil quality of alpine farmland and elucidate key factors influencing productivity levels under current agricultural paradigm, we conducted an extensive collection samples. In total, 234 samples (0–20 cm) were collected from Menyuan County, heartland southern slope Qilian Mountains. These represented four predominant types, including cold calcic soil, luvic chernozem, calcareous meadow gray cinnamon soil. Moreover, by employing principal component analysis, established a...

Carbon isotope discrimination (Δ) has been proposed as an indirect estimation criterion for water use efficiency in C3 plants. Because of the higher cost Δ analysis, ash content or K concentration alternative many species. In five typical habitats extreme arid Ejina desert oasis northwest China, seasonal variations foliar δ, content, and potassium (K) were researched two constructive riparian plants (Populus euphratica Olivier, Tamarix ramosissima Ledeb). The correlations with both species...

Estimating accurately the vegetation water consumption (VWC) in Qinghai Lake Basin (QLB) is conducive to effective utilization and management of resources QLB, which great significance construction a national park QLB. We used Geographic Information System (GIS) technology remote sensing (RS) based on potential evapotranspiration data calculate VWC QLB from 2000 2020, analyzed influencing factors 2020. The results showed that (1) average value varied 242.96 mm 287.99 mm, was 267.07 total...

The Datong River source region in the Northeast Qinghai-Tibetan Plateau Climate change and anthropogenic factors are most important influencing runoff. Land use/land cover (LULC) is an factor that has a significant impact on runoff changes. Quantifying variation characteristics determining effect of changes climate LULC for water resource management application. mathematical statistics analysis soil assessment tool (SWAT) were combined to perform comprehensive based meteorological...

In recent years, the ecological and environmental problems caused by mining in Qilian Mountains have attracted considerable attention, government has carried out a number of comprehensive environment remediation projects there, among which restoration Mountain alpine area is an essential task. As result, heavy metals been studied soil area. This can provide scientific basis data support for establishment demonstration index monitoring areas. order to understand content contamination status...