A5037737884- Electrocatalysts for Energy Conversion
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Advanced battery technologies research
- Pharmacological Effects of Natural Compounds
- Catalytic Processes in Materials Science
- Curcumin's Biomedical Applications
- Supercapacitor Materials and Fabrication
- Ubiquitin and proteasome pathways
- Cytokine Signaling Pathways and Interactions
- RNA Interference and Gene Delivery
- Surfactants and Colloidal Systems
- Fuel Cells and Related Materials
- Nanoparticle-Based Drug Delivery
- Nanocomposite Films for Food Packaging
- Nanoporous metals and alloys
- Cancer-related Molecular Pathways
- CAR-T cell therapy research
- Drug Solubulity and Delivery Systems
- Protein Degradation and Inhibitors
- Cancer Research and Treatments
- Virus-based gene therapy research
- Synthesis and Catalytic Reactions
- Chemical synthesis and alkaloids
- Natural product bioactivities and synthesis
Nankai University
2024
National Vaccine and Serum Institute
2024
Second Affiliated Hospital of Nanjing Medical University
2024
Anhui Medical University
2023-2024
China National Biotechnology (China)
2024
Shanghai Institute of Materia Medica
2018-2024
Chinese Academy of Sciences
2018-2024
State Key Laboratory of Medicinal Chemical Biology
2024
Anhui Science and Technology University
2021
Anhui University of Science and Technology
2021
PD-1/PD-L1 antibodies have achieved great success in clinical treatment. However, monoclonal antibody drugs also challenges, such as high manufacturing costs, poor diffusion, low oral bioavailability and limited penetration into tumour tissue. The development of small-molecule inhibitors interaction represents a promising perspective to overcome the above challenges cancer immunotherapy.We explored structural activity relationships used biochemical assays generate lead compound (ZE132). CD8+...
Ketoconazole is a broad spectrum imidazole antifungal drug. For the treatment of superficial fungal infections with ketoconazole, it needs to be permeated deep skin layers. In order develop topical formulation ketoconazole for improving its deposition and water-solubility, ketoconazole-loaded methoxy poly (ethylene glycol)-b-poly (δ-valerolactone) micelles were developed through thin-film hydration method. Particle size, drug loading capacity, infrared X-ray diffraction drug-loaded...
Ultralow loading palladium nanoparticles were facilely synthesized on a three-dimensional graphite-coated nickel foam support by metal atomic layer deposition technology and used as promising catalyst for ethanol electro-oxidation reaction.
Novel WN FNs/N–C consisting of nanosheets with flower-like morphology and N–C composites was prepared an improved ORR performance.
Honokiol-loaded micelles were prepared by emulsion-solvent evaporation procedure when oligochitosan-pluronic conjugate (CS-F127) as carrier. Differential scanning calorimetry (DSC) indicated that honokiol existed in amorphous form it was encapsulated into the with 87.54 ± 1.52% of encapsulation efficiency (EE) and 12.51 0.22% drug loading (DL) capacity. The water-solubility increased to 1.46 mg/mL, being >27-folds higher than pure honokiol. vitro release study demonstrated a slow sustained...