A5101519211- Bacillus and Francisella bacterial research
- Viral Infections and Outbreaks Research
- Zoonotic diseases and public health
- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Neurological diseases and metabolism
- Virus-based gene therapy research
- Biomedical Ethics and Regulation
- Metabolism and Genetic Disorders
- Genomics and Phylogenetic Studies
- Bioinformatics and Genomic Networks
- Gene expression and cancer classification
- Pharmaceutical Economics and Policy
- Disaster Response and Management
- Mitochondrial Function and Pathology
- Ethics in Clinical Research
National Institute of Allergy and Infectious Diseases
2008-2024
National Institutes of Health
2001-2024
The Francis Crick Institute
2024
Our current biological knowledge is spread over many independent bioinformatics databases where different types of gene and protein identifiers are used.The heterogeneous redundant nature these limits data analysis across resources.It an even more serious bottleneck for larger datasets, such as lists derived from microarray proteomic experiments.The DAVID Gene ID Conversion Tool (DICT), a web-based application, able to convert user's input or product one type another in comprehensive...
Abstract Background The ability of recombinant adeno-associated virus to transduce preimplantation mouse embryos has led the use this delivery method for production genetically altered knock-in mice via CRISPR-Cas9. potential exists simplify and extend types alleles that can be generated directly in zygote, obviating need manipulations genome embryonic stem cell route. Results We present data from a total 13 models using CRISPR-Cas9 electroporation zygotes donor repair templates transduction...
The terrorist attacks of September 11 and the anthrax mailings a month later prompted sweeping response by federal government to improve preparedness US meet potential threat posed using biological agent. This transcended traditional interagency boundaries, creating new opportunities while producing unique fiscal leadership challenges. National Interagency Confederation for Biological Research has made significant progress over past 12 years because its ability adapt need cooperation...