- Single-cell and spatial transcriptomics
- Technology-Enhanced Education Studies
- Cancer Immunotherapy and Biomarkers
- Soil and Water Nutrient Dynamics
- Cancer Cells and Metastasis
- Sharing Economy and Platforms
- Education and Learning Interventions
- Technology Adoption and User Behaviour
- Technology Use by Older Adults
- Groundwater flow and contamination studies
- Impact of Technology on Adolescents
- Ferroptosis and cancer prognosis
- Cultural Heritage Management and Preservation
- Cancer Genomics and Diagnostics
- Hydrology and Watershed Management Studies
Wuhan University
2024-2025
Nanjing University of Posts and Telecommunications
2022-2024
Shanghai Institute of Technology
2022
Hohai University
2018
Abstract Colorectal cancer (CRC) is a heterogeneous disease that develops through stepwise accumulation, yet the underlying mechanisms at single-cell resolution remain unclear. Here, we profiled 751,531 transcriptomes, spatial transcriptomics, and snMultiomes from 142 multistage samples, revealing cellular molecular alterations dynamic intercellular crosstalk during CRC development. Additionally, created sc-eQTL map identifying 16,833 significant pairs across 28 cell subtypes, with over 76%...
To improve the happiness of older adults enjoying digital public services, this study examines structural relationship among self-perception aging, subjective well-being, technology anxiety, self-efficacy, perceived usefulness, and intention to use services for in context services. We employ Structural Equation Modeling (SEM) empirical analysis (N = 345, February October 2023). The negative aging may lead emotions on technology, which will reduce well-being increase anxiety. Technology...
With the widespread implementation of COVID-19 prevention and control measures during pandemic, online classes have become a normal indispensable part college students' lives. Analysis factors affecting behavioural intention towards will help improve class quality. This paper sets up model to analyse that may affect such intentions . The results show social influence, performance expectancy, effort perceived usefulness ease use significant positive effect on intention, enabling...
Nowadays, cultural self-confidence is increasingly emphasized. The architectural field also paying more and attention to traditional Chinese architecture. contemporary expression of the spatial characteristics buildings especially valued. This article discusses modern space creation strategy based on composition Western Sichuan. In addition, it was verified in practice with unlimited bookstore project Santai Middle School Mianyang City. First, we conducted an analysis climate adaptability...