A5013026262- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Radiation Effects and Dosimetry
- Occupational and environmental lung diseases
- Head and Neck Surgical Oncology
- Advanced Neuroimaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Pleural and Pulmonary Diseases
- Oral health in cancer treatment
- Radiation Effects in Electronics
- Atomic and Subatomic Physics Research
- Advanced MRI Techniques and Applications
- Particle Accelerators and Free-Electron Lasers
- Fetal and Pediatric Neurological Disorders
- Brain Tumor Detection and Classification
- Effects of Radiation Exposure
- Nutritional Studies and Diet
- Immune cells in cancer
- Connexins and lens biology
- Digital Imaging for Blood Diseases
Second Military Medical University
2024
Eastern Hepatobiliary Surgery Hospital
2024
Nanjing University
2023
Nanjing Foreign Language School
2023
The University of Texas MD Anderson Cancer Center
2011-2020
Shanghai Chest Hospital
2019
Shanghai Jiao Tong University
2019
NKT Holding (Denmark)
2016
Scripps (United States)
2012
Scripps Institution of Oceanography
2012
Abstract Background Combining photon or proton radiotherapy with targeted therapy shows promise for head and neck cancer (HNSCC). The poly (adenosine diphosphate [ADP]‐ribose) polymerase‐1/2 inhibitor niraparib targets DNA damage repair (DDR). We evaluated the effects of in combination photons protons, its on relative biological effectiveness (RBE) human HNSCC cell lines. Methods Radiosensitivity was assessed RBE calculated clonogenic survival assays; unrepaired double‐strand breaks were...
Postoperative radiation therapy can improve control for adenoid cystic carcinoma (ACC) of the head and neck; however, delivering adequate dose to tumor bed must be balanced with limiting nearby critical organs. Intensity-modulated proton (IMPT) may help therapeutic ratio, though concerns exist regarding tissue heterogeneity other sources uncertainty in several neck subsites. We report toxicity outcomes patients ACC treated at a single institution postoperative IMPT robust planning...
Purpose: Fair comparisons between x‐ray IMRT and Proton therapy plans should include assessment of plan robustness. However, this is difficult because the dose distribution can be altered in presence uncertainties different ways for each modality. In order to fairly evaluate plan's robustness both arms, we propose use statistical parameters assess probabilistic DVHs under setup range uncertainties. Methods: A lung cancer patient currently undergoing randomized trial was selected study....
Purpose: To assess the feasibility of an online adaptive proton therapy technique for discrete spot scanning (SSPT) to correct interfractional anatomic changes. Methods: An algorithm was developed compensate range changes without full reoptimization. The individual energies from original treatment plan were adjusted match new anatomy based on water equivalent pathlength distal edge target a ray‐by‐ray basis. Remaining spots outside (proximal‐ and lateral‐to) then removed or added if...
Purpose: Diffusion tensor imaging (DTI) can measure molecular mobility at the cellular level, quantified by apparent diffusion coefficient (ADC). DTI may also reveal axonal fiber directional information in white matter, fractional anisotropy (FA). Juvenile pilocytic astrocytoma (JPA) is a rare brain tumor that occurs children and young adults. Proton therapy (PT) increasingly used treatment of pediatric tumors including JPA. However, response both normal tissues to PT currently under...
Strategies for treating thoracic and liver tumors using pencil beam scanning proton therapy Thoracic have not been treated with (PBS) until recently. This is because of concerns about the significant interplay effects between spot patient's respiratory motion. However, all unacceptable magnitude motion PBS therapy. Therefore it important to analyze understand significance effect each patient. The factors that affect its washout include motion, size, sequence speed. Selection angle,...