A5101535923- Gut microbiota and health
- Colorectal Cancer Screening and Detection
- Metabolomics and Mass Spectrometry Studies
- Colorectal Cancer Treatments and Studies
- Vascular Tumors and Angiosarcomas
- Cancer, Lipids, and Metabolism
- Tryptophan and brain disorders
- Cutaneous lymphoproliferative disorders research
- Radiomics and Machine Learning in Medical Imaging
- Alzheimer's disease research and treatments
- Mycobacterium research and diagnosis
- CNS Lymphoma Diagnosis and Treatment
Guangzhou University of Chinese Medicine
2023-2024
Guangxi Medical University
2024
Gut microbiota has demonstrated an increasingly important role in the onset and development of colorectal cancer (CRC). Nonetheless, association between gut KRAS mutation CRC remains enigmatic. We conducted 16S rRNA sequencing on stool samples from 94 patients employed linear discriminant analysis effect size algorithm to identify distinct mutant wild-type patients. Transcriptome data nine were transformed into a matrix immune infiltrating cells, which was then utilized explore...
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder for which no effective therapy currently available. Given that various attempts to target beta-amyloid (Aβ) have been unsuccessful in clinical trials, other potential pathogenic factors such as brain energy metabolism (EM) attracted increasing attention. Traditional Chinese medicines, including danggui-shaoyao-san (DSS), play a notable role AD. However, it remains unclear whether DSS exerts therapeutic effects on AD...
Colorectal cancer (CRC) is the most common gastrointestinal malignancy worldwide, with obesity-induced lipid metabolism disorders playing a crucial role in its progression. A complex connection exists between gut microbiota and development of intestinal tumors through metabolite pathway. Metabolic frequently alter microbiome, impairing immune cellular functions hastening
ABSTRACT This study aims to determine whether gender is a factor in the interplay between human intestinal flora and colorectal cancer (CRC), ultimately providing new evidence for clinical prediction management of CRC different genders. In this study, we included 186 untreated patients, classified them into two groups based on pathological staging: Groups Ⅰ–Ⅱ Ⅲ–Ⅳ, with male female within each group. We collected preoperative fecal samples from these patients performed 16S rRNA gene...
乳腺原发性获得性渐进性淋巴管瘤（acquired progressive lymphangioma，APL）是一种罕见的良性肿瘤。本文报道1例原发于乳腺的APL，广泛累及单侧乳腺区至腋下皮肤；形态学上，肿瘤主要由相互吻合的不规则或分支状的薄壁淋巴管组成，形成大小不一、形态不规则的腔隙结构，腔隙内衬形态温和的单层扁平细胞，腔内淋巴细胞积聚；间质有少量稀疏纤维组织及淋巴细胞成分。免疫组织化学：淋巴管样内皮细胞D2-40、CD31阳性，管壁及间质细胞结蛋白阳性，淋巴管周围纤维组织Masson染色阳性。病变呈良性进程，局部缓慢持续性进展，病理诊断需与分化好的血管肉瘤相鉴别。.