Siyi Tan

ORCID: 0009-0003-4700-0251
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About
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Adenosine and Purinergic Signaling
  • Advanced Nanomaterials in Catalysis
  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Virus-based gene therapy research
  • Extracellular vesicles in disease
  • Hemoglobin structure and function
  • melanin and skin pigmentation
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • CAR-T cell therapy research
  • Viral Infections and Vectors
  • Periodontal Regeneration and Treatments
  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Monoclonal and Polyclonal Antibodies Research
  • Muscle Physiology and Disorders
  • Skin Protection and Aging
  • Bone Tissue Engineering Materials
  • Bacteriophages and microbial interactions
  • Genetic and Environmental Crop Studies
  • Dermatology and Skin Diseases
  • Cancer Immunotherapy and Biomarkers
  • Agricultural pest management studies

Julius Kühn-Institut
2025

Sun Yat-sen University
2021-2024

Fifth Affiliated Hospital of Sun Yat-sen University
2021-2024

Tianjin University of Traditional Chinese Medicine
2023

Panyu District Central Hospital
2020-2021

Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2021

Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2021

Jinan University
2015

Institute of Virology of the Slovak Academy of Sciences
1986

Abstract The pandemic of coronavirus disease 2019 (COVID‐19) is continually worsening. Clinical treatment for COVID‐19 remains primarily supportive with no specific medicines or regimens. Here, the development multifunctional alveolar macrophage (AM)‐like nanoparticles (NPs) photothermal inactivation capability reported. NPs, made by wrapping polymeric cores AM membranes, display same surface receptors as AMs, including receptor and multiple cytokine receptors. By acting decoys, NPs block...

10.1002/advs.202003556 article EN cc-by Advanced Science 2021-05-12

Abstract Legumes play a crucial role in agriculture and serve as valuable source of protein for human animal consumption. However, legumes are susceptible to various viral infections, which can cause significant losses yield quality. Chickpea ( Cicer arietinum L.) is an important food legume worldwide. While its cultivation Germany still infancy, it expected increase due numerous advantages. It adapted drought conditions, attractive additional option crop rotations organic farming gaining...

10.1007/s41348-024-01048-z article EN cc-by Journal of Plant Diseases and Protection 2025-01-11

The effectiveness of immune checkpoint inhibitor (ICI) therapy is hindered by the ineffective infiltration and functioning cytotoxic T cells immunosuppressive tumor microenvironment (TME). Signaling lymphocytic activation molecule family member 7 (SLAMF7) a pivotal co-stimulatory receptor thought to simultaneously trigger NK-cell, T-cell, macrophage antitumor cytotoxicity. However, potential this collaborative stimulation in immunity for solid tumors underexplored due exclusive expression...

10.1158/2326-6066.cir-23-1102 article EN Cancer Immunology Research 2024-05-30

Common antigenic properties for p85 and p75 but a different character p71 Aleutian disease virus (ADV) proteins were demonstrated by Western blot analysis with monoclonal antibodies. It was shown that four hybridomas (ADV-Hy 47, 66, 77 84) specific reactivity structural also recognized p25 not the p71, nonstructural, protein. In turn, antibody ADV-Hy 2 protein only. For further studies of their properties, ADV subjected to enzymatic or chemical cleavage. The derived peptide fragments...

10.1159/000149684 article EN Intervirology 1986-01-01

Vertical bone augmentation without osseous walls to support the stability of clots and grafts remains a challenge in dental implantology. The objectives this study were confirm that cortical perforation recipient bed is necessary evaluate whether nanohydroxyapatite (nHA) block coated with recombinant human vascular endothelial growth factor165 (rhVEGF165) can improve vertical regeneration.We prepared nHA blocks or rhVEGF165 on rabbit calvarium through perforation, designated animals as...

10.2147/ijn.s268182 article EN cc-by-nc International Journal of Nanomedicine 2020-12-01

Psoriasis is a chronic inflammatory skin disease that associated with multiple coexisting conditions. Extensive literature suggests psoriasis T-cell-mediated condition, and its pathogenesis related to dysfunction of the immune system. Myeloid-derived suppressor cells (MDSCs) are group heterogeneous myeloid have suppressive effects on T cells. MDSCs present at very low levels in healthy individuals but can substantially expand tumours or PSORI-CM02, Chinese medical formula designed based...

10.3389/fphar.2020.563433 article EN cc-by Frontiers in Pharmacology 2021-01-18
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