A5055747339- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Photoreceptor and optogenetics research
- Neuropeptides and Animal Physiology
- Ion Channels and Receptors
- Minerals Flotation and Separation Techniques
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Hypothalamic control of reproductive hormones
- Sleep and Wakefulness Research
- Neurogenesis and neuroplasticity mechanisms
- Ion channel regulation and function
- Herbal Medicine Research Studies
- Memory and Neural Mechanisms
Jiangsu University
2019-2024
Hunan University
2024
Neurotensin (NT) is an endogenous tridecapeptide in the central nervous system. NT-containing neurons and NT receptors are widely distributed spinal dorsal horn (SDH), indicating their possible modulatory roles nociception processing. However, exact distribution function of NT, as well (NTRs) expression SDH, have not been documented. Among four NTR subtypes, NTR2 predominantly involved analgesia according to previous reports. SDH has yet directly elucidated. Specifically, it remains unclear...
Abstract The substantia gelatinosa (SG, lamina II of spinal cord gray matter) is pivotal for modulating nociceptive information from the peripheral to central. γ-Aminobutyric acid type B receptors (GABA Rs), metabotropic GABA receptor subtype, are widely expressed in pre- and postsynaptic structures SG neurons. Activation Rs by exogeneous agonists induces both inhibitions. However, actions endogenous via presynaptic on glutamatergic synapses, interaction with glutamate, remain elusive. In...