A5051358614- Infant Nutrition and Health
- Mycorrhizal Fungi and Plant Interactions
- Food Allergy and Anaphylaxis Research
- Asthma and respiratory diseases
- Digestive system and related health
- Child Nutrition and Feeding Issues
- Pharmaceutical studies and practices
ABSTRACT Prior to the introduction of novel food ingredients into supply, safety risk assessments are required, and numerous prediction models have been developed validated evaluate safety. The allergenic potential Helaina recombinant human lactoferrin (rhLF, Effera™), produced in Komagataella phaffii ( K. ) was assessed by literature search, bioinformatics sequence comparisons known allergens, glycan allergenicity assessment, a simulated pepsin digestion model. search identified no for...
Lactoferrin (LF) is a major component of human milk. LF supplementation (currently bovine) supports the immune system and helps maintain iron homeostasis in adults. No recombinant lactoferrin (rhLF) available for commercial food use. To determine extent to which rhLF (Effera™) produced by Komagataella phaffii digests similarly hmLF, validated vitro digestion protocol was carried out. Bovine (bLF) used as an additional control, it approved use various categories. This study compared intact...
Introduction Prior to the introduction of novel food ingredients into supply, safety risk assessments are required, and numerous prediction models have been developed validated evaluate safety. Methods The allergenic potential Helaina recombinant human lactoferrin (rhLF, Effera™), produced in Komagataella phaffii ( K. ) was assessed by literature search, bioinformatics sequence comparisons known allergens, glycan allergenicity assessment, a simulated pepsin digestion model. Results search...