A5017662027- Computational Drug Discovery Methods
- Pharmaceutical Quality and Counterfeiting
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Pharmacogenetics and Drug Metabolism
- COVID-19 Clinical Research Studies
- Pharmacovigilance and Adverse Drug Reactions
- Cancer therapeutics and mechanisms
Peoples' Friendship University of Russia
2023-2024
The novel coronavirus infection (COVID-19) is characterized by damage, along with the lungs, to many other vital organs and systems. prevalence severity of resulting lesions are determined ability SARS-CoV-2 virus cause excessive activation immune response, accompanied changes in both cellular humoral components. Among disorders, most significant hypersecretion cytokines, including interleukins (IL), particular IL-6 IL1β. Elevated levels one main predictors severe COVID-19 death. So,...
Nirmatrelvir is an antiviral drug that, in combination with ritonavir, effective agent for the etiotropic therapy of patients mild to moderate COVID-19. The aim study was evaluate bioequivalence generic nirmatrelvir Аrpaxel ritonavir and original Paxlovid, which a nirmatrelvir/ritonavir, single dose administration healthy volunteers. Materials methods. This research open-label, randomized, two-period crossover study. It included 2 periods, each volunteers received either test (nirmatrelvir...