A5080472159- bioluminescence and chemiluminescence research
- HIV Research and Treatment
- Gut microbiota and health
- Bacterial biofilms and quorum sensing
- Metabolomics and Mass Spectrometry Studies
- Epigenetics and DNA Methylation
- Redox biology and oxidative stress
- Legionella and Acanthamoeba research
- Vibrio bacteria research studies
University of Pittsburgh
2023
Wake Forest University
2023
Previous studies have suggested that a relationship exists between severity and transmissibility of malaria variations in the gut microbiome, yet only limited information on temporal dynamics microbial community during malarial infection. Here, using rhesus macaque model relapsing malaria, we investigate how affects microbiome. In this study, performed 16S sequencing DNA isolated from rectal swabs macaques over course an experimental infection with Plasmodium cynomolgi analyzed bacterial...
ABSTRACT Many pathogenic bacteria, including Legionella pneumophila , infect humans from environmental reservoirs. To survive in these reservoirs, bacteria must withstand microbe-on-microbe competition. We previously discovered that L. can compete with neighboring via an antimicrobial metabolite called homogentisic acid (HGA). Curiously, strains secrete HGA are not wholly immune to its effects: low-density strongly inhibited by HGA, whereas high-density cells tolerant. How do tolerate and...
Abstract Many pathogenic bacteria, including Legionella pneumophila , infect humans from environmental reservoirs. To survive in these reservoirs, bacteria must withstand microbe-on-microbe competition. We previously discovered that L. can compete with neighboring via an antimicrobial metabolite called homogentisic acid (HGA) (Levin, Goldspiel, and Malik 2019). Curiously, strains secrete HGA are not wholly immune to its effects: low-density strongly inhibited by whereas high-density cells...