A5068380043- Autoimmune and Inflammatory Disorders Research
- Lipid metabolism and disorders
- Inflammation biomarkers and pathways
- Sepsis Diagnosis and Treatment
- Systemic Lupus Erythematosus Research
- Immune Cell Function and Interaction
- Solid-state spectroscopy and crystallography
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
- Complement system in diseases
- Vitamin D Research Studies
- Immunotherapy and Immune Responses
- Infrared Thermography in Medicine
- Virus-based gene therapy research
- Adolescent and Pediatric Healthcare
- Renin-Angiotensin System Studies
- Nitric Oxide and Endothelin Effects
- Cell Adhesion Molecules Research
- Pharmacological Effects of Natural Compounds
- Systemic Sclerosis and Related Diseases
- Peroxisome Proliferator-Activated Receptors
- Receptor Mechanisms and Signaling
- Eosinophilic Disorders and Syndromes
- Cancer, Lipids, and Metabolism
Xuzhou Medical College
2008-2025
Affiliated Hospital of Xuzhou Medical College
2008-2024
BACKGROUND:Calcitriol (1 alpha, 25-dihydroxy vitamin D3) is a good D supplement but can cause hypercalcemia. Whereas, 22-oxa-1 D3 (22-oxa-calcitriol) has less hypercalcemic activity than calcitriol and reported to be effective for cell-proliferative diseases. The objective of the study was compare renal function blood tests arthritis patients receiving supplements with those 22-oxa-calcitriol supplements. MATERIAL AND METHODS:A total 369 clinically confirmed rheumatoid were included in this...
Interferon-γ (IFN-γ) is a versatile cytokine which broadly involves in the inflammatory diseases, mediating both immune activation and tolerance. Here, we aimed to investigate role of IFN-γ initiation adjuvant-induced arthritis (AIA).In an AIA mice model, increasing mRNA was observed at day 3 peaked on 7. At 3, majority IFN-γ-producing cells were located around vessels by immunofluorescent staining. Recombinant or anti-IFN-γ antibody injected into paw 2 study outcome AIA. The recipients...
Abstract Objective The differential diagnosis between adult-onset Still’s disease (AOSD) and sepsis has always been a challenge. In this study, machine learning model for of AOSD was developed an online platform to facilitate the clinical application model. Methods All data were collected from 42 patients 50 admitted Affiliated Hospital Xuzhou Medical University December 2018 2021. addition, 5 10 diagnosed in our hospital after March 2022 external validation. models built using scikit-learn...
<title>Abstract</title> Objective We here investigate the relationship between appearance of skin rash, complement, and risk systemic lupus erythematosus nephritis. Methods All data were collected from 71 patients with SLE (without LN) 200 LN treated at our hospital August 2018 to 2023. The latter group was further categorized into a high eGFR (eGFR ≥ 60 ml/min; 100 cases) low < cases). Basic clinical characteristics such as gender, age, fever, joint pain, hair loss, along laboratory...
Aims/Background Adult-onset Still’s disease (AOSD) shares similar clinical symptoms with sepsis. Thus, differentiating between AOSD and sepsis presents a great challenge while making diagnosis. This study aimed to analyse the changes in blood microbiota related using metagenomic next-generation sequencing (mNGS), identify potential biomarkers that distinguish from sepsis, explore diagnostic value of mNGS differentiation these two pathological conditions. Methods Clinical data four patients...
Abstract Objective. The differential diagnosis between Adult-onset Still's disease (AOSD) and sepsis has always been a challenge. In this study, machine learning model for of AOSD was developed an online platform to facilitate the clinical application model. Methods. All data were collected from 42 patients 50 admitted Affiliated Hospital Xuzhou Medical University December 2018 2021. addition, 5 10 diagnosed in our hospital after March 2022 external validation. models built using...
Introduction: Adult-Onset Still’s Disease (AOSD) shares similar clinical symptoms with Sepsis. Diagnosis between AOSD and Sepsis is a great challenge. To compare blood microbiota of The structure diversity in patients will be initially explored, analyzing the microecological changes finding potential biomarkers Sepsis.Method: total nucleic acid samples were extracted sequenced by metagenomic next-generation sequencing (mNGS) from October 2021 to February 2022. report was analyzed for...