A5057293747- Bladder and Urothelial Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Urinary and Genital Oncology Studies
- Immunodeficiency and Autoimmune Disorders
- Hepatitis B Virus Studies
- Pancreatic function and diabetes
- Diabetes Management and Research
- Diabetes and associated disorders
- Ureteral procedures and complications
- Hepatitis C virus research
- Urological Disorders and Treatments
- Blood disorders and treatments
- Liver Disease Diagnosis and Treatment
- IgG4-Related and Inflammatory Diseases
Tenri Hospital
2024
Hoshigaoka Medical Center
2022
Intravenous immunoglobulins (IVIgs) derived from the pooled plasma of thousands donors contain numerous types IgG molecules, including autoantibodies commonly used to diagnose autoimmunity. While these can cause misinterpretation serological tests for IVIg recipients, their profiles in preparations are not fully understood.
To investigate the organ-specific response and clinical outcomes of mixed responses (MRs) to immune checkpoint inhibitors (ICIs) for unresectable or metastatic urothelial carcinoma (ur/mUC), we retrospectively analyzed 136 patients who received pembrolizumab. The total objective rate (ORR) ORR were determined each lesion according Response Evaluation Criteria in Solid Tumors version 1.1 as follows: (i) complete (CR), (ii) partial (PR), (iii) stable disease (SD), (iv) progressive (PD). Most...
Intravenous immunoglobulins (IVIgs) contain various autoantibodies, including those against glutamic acid decarboxylase (GADAb), a valuable biomarker of type 1 diabetes mellitus. Passive transfer GADAb from IVIgs to patients poses risk misdiagnosis, and information on the specific titres their impact diagnostic accuracy remains limited. This study aimed provide further insights into origin detected in patient serum following IVIg infusion.
In order to treat the iatrogenic ureteral stricture of more than 8 cm length after transurethral ureterolithotripsy, we planned perform ureterocystoneostomy with psoas hitch and Boari flap. Because longer defect affected ureter presurgically expected rigid thickened stump resulting from chronic inflammation, anti-reflux technique by forming submucosal tunnel could not be achieved as in standard flap reluctantly anastomosed end tubularized bladder wall end-to-end fashion. secure mechanism...