A5064296815- Physics of Superconductivity and Magnetism
- Superconducting Materials and Applications
- HVDC Systems and Fault Protection
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Urinary and Genital Oncology Studies
- Frequency Control in Power Systems
- Organ Transplantation Techniques and Outcomes
- Magnetic and transport properties of perovskites and related materials
- Particle accelerators and beam dynamics
- Photonic and Optical Devices
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Prostate Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Magnetic confinement fusion research
- Cancer Research and Treatments
- Photonic Crystals and Applications
- PI3K/AKT/mTOR signaling in cancer
- Renal cell carcinoma treatment
- Spacecraft and Cryogenic Technologies
- Railway Systems and Energy Efficiency
- Magnetic Properties and Applications
Jikei University Kashiwa hospital
2022-2025
Osaka University of Pharmaceutical Sciences
2021-2025
Weatherford College
2021
Nara Medical University
2003-2020
Osaka Medical and Pharmaceutical University
2018-2020
Fuji Electric (Japan)
2006-2019
Creative Commons
2019
Osaka Hospital
2017
Kagawa Prefectural Central Hospital
2015
Saiseikai Suita Hospital
2014
Sarcopenia is a muscle loss syndrome known as risk factor of various carcinomas. The impact sarcopenia and sarcopenia-related inflammatory/nutritional markers in metastatic urothelial carcinoma (mUC) treated with pembrolizumab was unknown, so this retrospective study 27 patients performed. Psoas mass index (PMI) calculated by bilateral psoas major area at the L3 computed tomography. cut-off PMI value for defined ≤6.36 cm2/m2 men ≤3.92 women. Neutrophil-to-lymphocyte ratio (NLR) ≥ 4.0...
Real-world evidence regarding enfortumab vedotin for unresectable or metastatic urothelial carcinoma is scarce, particularly in Japan. We investigated real-world data focusing on patient background, previous treatments, response, survival and adverse events patients receiving vedotin.
Primary androgen deprivation therapy (PADT) is the most effective systemic for patients with metastatic prostate cancer. Nevertheless, once PSA progression develops, prognosis serious and mortal. We sought to identify factors that predicted in a series of Two-hundred eighty-six cancer who received PADT from 1998 2005 Nara Uro-Oncology Research Group were enrolled. The log-rank test Cox's proportional hazards model used determine predictive prognosis; rate castration-resistant (CRPC) overall...
Recently, several systemic inflammation-based scores, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), modified Glasgow prognostic score (GPS), and nutritional index (PNI), have been proposed factors for cancers. In this study, we aimed to determine the influence of scores nutrition status on outcome in patients receiving chemotherapy unresectable pancreatic cancer.A total 93 consecutive who underwent cancer at Osaka Medical College...
We designed and built a single-phase 1 MVA-22/6.9 kV HTS transformer with the multi-layered cylindrical windings composed of Bi2223 parallel conductors. In advance design, AC loss induced in was estimated on basis observed results strand. A subcooled liquid nitrogen cryogenic system corresponding cooling capacity developed attached to transformer. The actual measured by an electrical method. It great part total heat load dominated temperature rise nitrogen. discussed validity present...
Abstract Objective To develop the first Japanese real-world evidence of switch-maintenance avelumab in advanced, unresectable or metastatic urothelial carcinoma (aUC). Methods A multicenter-derived database registered 505 patients diagnosed with aUC between 2008 and 2021. Of these, 204 (40%) were selected stratified according to type therapy used: maintenance group (27 [5.3%]), second-line (2 L) pembrolizumab (103 [20%]) 2 L cytotoxic chemotherapy (74 [15%]). The progression-free survival...
It remains unclear whether patients with metastatic castration-sensitive prostate cancer (mCSPC) are suitable for upfront docetaxel therapy. Therefore, we retrospectively evaluated castration-resistant (mCRPC) who could not receive ≥6 cycles of mCRPC. This study enrolled 274 diagnosed mCSPC later developed mCRPC, data at diagnosis, including blood test results, available from 17 hospitals between 2008 and 2022. Failure to was defined as receiving ≤5 mCRPC or dying due without Factors...
<title>Abstract</title> Background To evaluate the efficacy of falciform ligament separating (FaLS) method, where was used to separate space between pancreaticojejunostomy (PJ) and hepatic, artery in pancreaticoduodenectomy (PD) for postoperative pancreatic fistula (POPF) management. Methods Patients who underwent PD at Osaka Medical Pharmaceutical University Hospital from January 2018 June 2024 were retrospectively reviewed. The harvested advance placed PJ hepatic artery. spaces above below...
Abstract The tumor suppressor gene MMAC/PTEN located on chromosome10q23.3 has dual phosphatase activity in the phosphoinositide-3-kinase signaling pathway and inhibits Akt activation, a serine-threonine kinase, which is involved proliferative antiapoptotic pathways. Furthermore, frequently inactivated variety of tumors including prostate cancer. In this study, we generated new type transfer drug, GelaTen, microsphere cationized gelatin hydrogels incorporating PTEN plasmid DNA. Using our...
In several malignant diseases, elevated heme oxygenase-1 (HO-1) is associated with progression or resistance to chemotherapy. We evaluated the clinical significance of HO-1 expression in non-muscle-invasive bladder cancer.We examined 109 patients cancer. The immunoexpression HO-1, p53, and Ki-67 was analyzed using paraffin-embedded tissue from transurethral resection comparison clinicopathological variables.Positive found 66 tumors (61%), positivity correlated significantly high tumor grade...
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> We designed and fabricated a 7.5 kW–360 rpm synchronous motor with superconducting rotor. The rotor was 6-pole type has no iron core. armature winding wound copper wires. 6 pieces of racetrack-shaped field coils were 5 mm wide <formula formulatype="inline"><tex Notation="TeX">$\hbox{RE}_{1}\hbox{Ba}_{2}\hbox{Cu}_{3}\hbox{O}_{7-\delta}$</tex> </formula> (REBCO, RE:Rare Earth) tapes produced by an...
Sorafenib and sunitinib are multi-kinase inhibitors with antitumor activity in patients advanced renal cell carcinoma (RCC). Several studies have evaluated the effect of sorafenib/sunitinib combination chemotherapeutic agents different types tumor. However, few addressed fluorinated pyrimidine sorafenib/sunitinib. In this study, we examined potential therapy 5FU human RCC lines. Three lines, ACHN, Caki-1 Caki-2, were used to assess sensitivity 5-fluorouracil (5FU), sorafenib alone or using...
The authors designed and fabricated a 1 T cryocooler-cooled pulse coil operating at 40 K. A 4-strand interlayer-transposed parallel conductor composed of Bi-2223 rectangular cross-sectional multifilamentary wires was adopted to realize uniform current distribution reduce the AC loss density down level that single strand. is 16-layer solenoidal one with an inner diameter 52 mm, outer 111 mm height 120 mm. heat drains AlN plates, which are insulators, arranged between layers for cooling due by...
Because pancreatic cancer is a disease with dismal prognosis due to the high rate of early recurrence even after curative surgery, selecting most effective treatment in an individual requires preoperative assessment tumor characteristics, including potential for recurrence. The study cohort included 84 patients undergoing surgical resection cancer. Univariate and multivariate analyses were conducted identify risk factors within six months resection. Early was associated platelet-lymphocyte...
The aim of this study is to investigate the prognostic relevance best objective response metastatic target lesions during sunitinib treatment in patients with renal cell carcinoma. Radiographic analysis according Response Evaluation Criteria Solid Tumors was assessed 50 patients. Clinicopathological characteristics including Heng risk classification and sunitinib-related adverse reactions were compared among four patient subgroups [complete or partial (CR/PR), stable disease (SD),...