A5111950548- Bacteriophages and microbial interactions
- RNA modifications and cancer
- Molecular Biology Techniques and Applications
- Dendrimers and Hyperbranched Polymers
- Pesticide Exposure and Toxicity
- Rheology and Fluid Dynamics Studies
- Probabilistic and Robust Engineering Design
- Advanced biosensing and bioanalysis techniques
- RNA and protein synthesis mechanisms
- Biochemical and Structural Characterization
- Computational Drug Discovery Methods
- Conducting polymers and applications
- Mycobacterium research and diagnosis
- Cancer-related molecular mechanisms research
- Quantum chaos and dynamical systems
- Protein Structure and Dynamics
- RNA Research and Splicing
- Molecular Junctions and Nanostructures
- Force Microscopy Techniques and Applications
- RNA Interference and Gene Delivery
- Photochemistry and Electron Transfer Studies
- Model Reduction and Neural Networks
- Photopolymerization techniques and applications
- Scientific Research and Discoveries
Columbia University
2011
University of Michigan–Ann Arbor
2009-2010
The energetics, stoichiometry, and structure of poly(amidoamine) (PAMAM) dendrimer−phospholipid interactions were measured with isothermal titration calorimetry (ITC), transmission electron microscopy (TEM), atomic force (AFM), dynamic light scattering (DLS), molecular dynamics (MD) simulations. Dendrimers sixth-generation smaller interacted the lipids at an average stoichiometry enthalpy proportional to number primary amines per dendrimers (4.5 ± 0.1 lipids/primary amine 6.3 0.3 kJ/mol...
Abstract In this manuscript we report the crosslinking of pre‐existing macromolecules in solution through use photoactive benzophenone chromophores. We show that a bifunctional crosslinker composed two chromophores as well single chromophore crosslink poly (butadiene) and (ethylene oxide) to form insoluble gels when irradiated with UV light. The molecular weight between crosslinks photogenerated was compared for crosslinkers, an equivalent amount each solution, by measuring swelling ratio...
In this work, we seek to simulate rare transitions between metastable states using score-based generative models. An efficient method for generating high-quality transition paths is valuable the study of molecular systems since data often difficult obtain. We develop two novel methods path generation in paper: a chain-based approach and midpoint-based approach. The first biases original dynamics facilitate transitions, while second mirrors splitting techniques breaks down into smaller...