- Optical Coherence Tomography Applications
- Coronary Interventions and Diagnostics
- Photoacoustic and Ultrasonic Imaging
- Advanced Fluorescence Microscopy Techniques
- Ultrasound Imaging and Elastography
- Congenital heart defects research
- Optical Imaging and Spectroscopy Techniques
Northeastern University
2022-2025
Universidad del Noreste
2022
SignificanceThe deep cortical microvasculature is closely linked to the pathogenesis of Alzheimer's disease (AD). However, tail artifacts from superficial vessels often interfere with detecting in optical coherence tomography angiography (OCTA) imaging. A more accurate method assess vasculature crucial for understanding its relationship AD onset.AimWe aim reduce vessel OCTA imaging and improve visualization analysis an mouse model.ApproachWe introduced attenuation coefficient decorrelation...
We proposed a non-contact photoacoustic (PA) detection method using spectral domain optical coherence tomography (SDOCT). Two interference spectrums (A-lines) were acquired before and after the PA excitation with SDOCT. signal propagated within sample causing vibration. The vibration inner introduced phase change between two A-lines. Thus, can be detected by evaluating difference in Based on method, an OCT-PAM dual-mode imaging system was constructed. In system, SDOCT served as unit for PAM....
The stress phase angle (SPA), defined as the temporal between circumferential (CS) in arterial wall and shear (WSS), is utilized to investigate interactions CS WSS. SPA serves an important parameter for early diagnosis of cardiovascular disease. In this study, we proposed a novel method measuring using spectral domain optical coherence tomography (SD-OCT). multi-M-mode scan strategy adopted interference spectrum acquisition. phases WSS are extracted from corresponding structural flow...
Abnormal blood flow in the early stage of embryonic heart can lead to cardiac defects. Thus, accurate measurement is important for related studies. Optical coherence tomography (OCT) a noninvasive imaging approach which provide velocity distribution information with high spatial and temporal resolution. However, OCT only sensitive components parallel probing beam. To measure absolute velocity, additional information, such as Doppler angle, required. Here, we propose practical method angle by...
Optical coherence tomography (OCT) is a non-invasive imaging modality with high spatial resolution suitable for early embryonic heart imaging. However, the most commonly used OCT systems cannot provide direct 4-D due to acquisition speed limitations. We proposed retrospective gating reconstruction method based on spectral domain OCT. A special circuit was designed measure impedance change of chick embryos in response beating. The signal acquired simultaneously B-scan image sequence at...