- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Intensive Care Unit Cognitive Disorders
- Pharmaceutical Practices and Patient Outcomes
- Anesthesia and Sedative Agents
- Pharmacy and Medical Practices
- Colorectal and Anal Carcinomas
- BRCA gene mutations in cancer
- Long-Term Effects of COVID-19
- Pain Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Nutrition, Genetics, and Disease
- Uterine Myomas and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Medication Adherence and Compliance
- Hemodynamic Monitoring and Therapy
- Childhood Cancer Survivors' Quality of Life
- Patient Safety and Medication Errors
- Dermatological and COVID-19 studies
- Congenital Diaphragmatic Hernia Studies
- Pediatric Pain Management Techniques
- Hospital Admissions and Outcomes
- Radiation Therapy and Dosimetry
Athinoula A. Martinos Center for Biomedical Imaging
2023-2025
Harvard University
2023-2025
Massachusetts General Hospital
2023-2025
Imperial College London
2017-2022
Wishaw General Hospital
2012-2020
Brigham and Women's Hospital
2019
Princess Margaret Cancer Centre
2004-2018
University of Toronto
1995-2017
Troy University
2015-2016
Trillium Health Centre
2016
Abstract Aims To provide contemporary data on the implementation of European guideline recommendations for lipid-lowering therapies (LLTs) across different settings and populations how this impacts low-density lipoprotein cholesterol (LDL-C) goal achievement. Methods results An 18 country, cross-sectional, observational study patients prescribed LLT primary or secondary prevention in care Europe. Between June 2017 November 2018, were collected at a single visit, including preceding 12 months...
Background and Purpose Current methods of measuring carotid stenosis such as those used in the North American Symptomatic Carotid Endarterectomy Trial (NASCET) European Surgery (ECST) have limitations caused by difficulties normal width distal internal artery (ICA) or bulb. Methods We developed a new technique, Stenosis Index (CSI), based on known anatomic relationship between common (CCA) ICA (1.2×CCA diameter=proximal diameter). The diameter can therefore be calculated from direct...
Abstract Our group has shown that translocator protein (TSPO) levels, a putative marker of neuroinflammation, are increased in the brain and spinal cord patients with chronic low back pain (cLBP). Whether neuroinflammation might be therapeutic target for this condition is unknown. In phase II double-blind, placebo-controlled, randomized clinical trial, we sought to evaluate whether tetracycline antibiotic minocycline, which commonly used as glial inhibitor preclinical models, an effect on...
The objective of this study is to compare progression-free survival (PFS) and overall (OS) ovarian cancer patients treated with neoadjuvant chemotherapy surgery primary postoperative chemotherapy. Retrospective analysis from 1998 2003 116 was performed. Fifty women diagnosed by positive cytology received three cycles carboplatin paclitaxel. Thirty-six subsequently underwent cytoreductive completed further postoperatively. OS PFS were compared in 66 A statistically significant difference...
To determine the prescribing activity of different staff groups within intensive care unit (ICU) and combined high dependency (HDU), namely trainee consultant medical advanced nurse practitioners in critical (ANPCC); to number type prescription errors; compare error rates between raise awareness care.The introduction government legislation has led development non-medical roles acute care. This facilitated an opportunity for ANPCC working develop a role.The audit was performed over 7 days...
Low-density lipoprotein cholesterol (LDL-C) recommendations differ between the 2018 American College of Cardiology/American Heart Association (ACC/AHA) and 2019 European Society Cardiology/European Atherosclerosis (ESC/EAS) guidelines for patients with atherosclerotic cardiovascular disease (ASCVD) (< 70 vs. < 55 mg/dl, respectively). In DA VINCI study, residual risk was predicted in ASCVD patients. The extent to which relative absolute might be lowered by achieving ACC/AHA versus ESC/EAS...
Background The time to recovery from vapour anaesthesia is shortened by an increase in ventilation while maintaining normocapnia. Hypercapnia during emergence spontaneously breathing patients also increases anaesthetic clearance the brain increasing cerebral blood flow. We hypothesised that hypercapnia‐induced hyperpnoea accelerates sevoflurane compared standard protocol. Methods After Ethics Review Board approval, 44 ASA I ‐ III undergoing elective gynaecological surgery were randomised...
Background: There is a concern that obesity may play role in prolonging emergence from fat‐soluble inhalational anaesthetics. We hypothesized increased pulmonary clearance of isoflurane will shorten immediate recovery anaesthesia and post‐anaesthesia care unit (PACU) stay obese patients. Methods: After Ethics Review Board approval, 44 ASA I–III patients with BMI>30 kg/m 2 undergoing elective gynaecological or urological surgery were randomized after completion to either an isocapnic...
The aim of this study was to compare overall survival (OS), progression-free (PFS), and relapse patterns between different modalities treatment for uterine papillary serous carcinoma (UPSC). A retrospective review 124 patients with pathologically confirmed UPSC performed, whom, 97 were eligible study. Postoperative groups included adjuvant radiotherapy consisting whole abdomen a pelvic boost (abdominopelvic [APRT]) (55 patients), paclitaxel carboplatin chemotherapy (CT) six cycles followed...
Covens, A.; Rosen, B.; Murphy, J.; Laframboise, S.; DePetrillo, A. D.; Lickrish, G.; Colgan, T.; Chapman, W.; Shaw, P.