A5100767663- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Plant-Microbe Interactions and Immunity
- Escherichia coli research studies
- Cancer-related molecular mechanisms research
- Immune Response and Inflammation
- Acute Lymphoblastic Leukemia research
- Diabetes and associated disorders
- Inflammasome and immune disorders
- Fibroblast Growth Factor Research
- Chronic Lymphocytic Leukemia Research
- Bacterial biofilms and quorum sensing
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Plant nutrient uptake and metabolism
- Acute Myeloid Leukemia Research
- interferon and immune responses
- Vibrio bacteria research studies
- Epigenetics and DNA Methylation
- Tuberculosis Research and Epidemiology
- Plant Disease Resistance and Genetics
- Neonatal and Maternal Infections
- Antibiotic Resistance in Bacteria
- Plant Molecular Biology Research
Wuhan University
2023-2025
Renmin Hospital of Wuhan University
2023-2025
First Affiliated Hospital of Nanchang University
2025
Nanchang University
2025
First Affiliated Hospital of Jiangxi Medical College
2025
Wuhan Asia Heart Hospital
2023-2024
Wuhan Polytechnic University
2023-2024
Center of Hubei Cooperative Innovation for Emissions Trading System
2023-2024
China Tobacco
2023
Dalian University
2014
Porcine extraintestinal pathogenic
Objective Epigenetic alterations are critical regulators in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD); however, dynamic epigenomic landscapes not well defined. Our previous study found that H3K27ac and H3K9me3 play important roles regulating lipid pathways early stages MASLD. However, status inflammation still needs to be determined.
Abstract Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4), an emerging immune checkpoint molecule, exhibits therapeutic potential in acute myeloid leukemia (AML). While single nucleotide polymorphisms (SNPs) of genes have been extensively investigated AML, the association between LILRB4 genetic and clinical outcomes remains unexplored. We SNPs within immunoglobulin domain immunoreceptor tyrosine-based inhibitory motif (ITIM) regions 151 AML patients 203 controls. The...
Porcine extraintestinal pathogenic Escherichia coli (ExPEC) is a leading cause of death in pigs and has led to considerable economic losses for the pig industry. ExPEC infections often systemic inflammatory responses pigs, characterized by meningitis, arthritis, pneumonia, septicemia. Baicalin been reported possess potent anti-inflammatory activity, but its function porcine remains unknown. The aim this study was explore protective effect mechanism baicalin against ExPEC-induced 3D4/21...
The outcomes of redo mitral valve replacement (Re-MVR) in a small annulus with the use chimney technique are not well documented. purpose this study is to present our early experience group patients, illustrating periop-erative complications and mortality outcomes. From 2019 2020, 77 consecutive patients underwent Re-MVR because annulus. To evaluate heart structural integrity clinical outcomes, postoperative data echocardiograms were examined. mean age was 56.7 ± 15.98 years. All surgery,...
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic worldwide. The detailed epigenomic changes during fat accumulation in are not clear yet. Here, we performed ChIP-Seq analysis tissues of high-fat diet and regular chow mice investigated dynamic landscapes H3K27ac H3K9me3 marks on chromatin. We find that activated typical enhancers marked with enriched lipid metabolic pathways liver; however, super do change much. regions covered repressive mark seem to undergo great changes,...
The deletion of orphan response regulator CovR reduces the growth rate Streptococcus suis serotype 2 ( S. 2). In this study, metabolome and transcriptome profiling were performed to study mechanisms underlying poor caused by CovR. By comparing (Δ covR ) (SC19), 146 differentially accumulated metabolites (upregulated: 83 downregulated: 63) 141 expressed genes 86 55) identified. Metabolome functional annotation analysis revealed that Δ was inhibited imbalance aminoacyl tRNA biosynthesis (the...
Commando procedure, the surgical replacement of mitral and aortic valves combined with reconstruction fibrosa fibrous body, is a technical challenge in patients small annuli. In this study, we evaluated safety early outcomes "Chimney" modality annuli, after prior valve surgery, using self-assembled valved conduit.From April 2021 to 2022, 30 consecutive cases conduit other cardiac procedures, were fully performed for re-operative roots. Data obtained through medical record review, at Asian...
Outcome of redo-mitral valve replacement in the small mitral annulus with use chimney technology is not well documented. From 2019 to 2020, 77 consecutive patients underwent because a annulus. To evaluate heart structural integrity and clinical outcomes, postoperative data echocardiograms were examined. Mean age was 56.7 ± 15.98 years. All surgery which 62 replacements, 7 repairs, 8 double replacements. Preoperative Mitral mean gradient 18.07 9.40 mmHg. Postoperative prosthesis size 28.51...