A5053298845- Lymphoma Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Hematopoietic Stem Cell Transplantation
- Neutropenia and Cancer Infections
- Immunotherapy and Immune Responses
- Cancer Cells and Metastasis
- Acute Myeloid Leukemia Research
- Acute Kidney Injury Research
- Immune Cell Function and Interaction
- Renal and Vascular Pathologies
- Chronic Kidney Disease and Diabetes
- Multiple Myeloma Research and Treatments
- Virus-based gene therapy research
- Ovarian cancer diagnosis and treatment
- Esophageal Cancer Research and Treatment
- Viral-associated cancers and disorders
- Gastric Cancer Management and Outcomes
- T-cell and B-cell Immunology
- Polyomavirus and related diseases
- Cell death mechanisms and regulation
- Cancer Mechanisms and Therapy
- Inhalation and Respiratory Drug Delivery
- Radiopharmaceutical Chemistry and Applications
- Cancer therapeutics and mechanisms
- Digital Innovation in Industries
The University of Texas at San Antonio
2024
Technical University of Munich
2002-2013
Klinikum rechts der Isar
2002-2013
Mater Misericordiae University Hospital
2013
Charité - Universitätsmedizin Berlin
2012
Fraunhofer Institute for Process Engineering and Packaging
2011
Klinik für Psychosomatik
2008
Heinrich Heine University Düsseldorf
1999
Universität Ulm
1986-1997
Max Delbrück Center
1995-1996
Twenty‐eight cases of monocytoid B‐cell lymphoma lymph nodes and 16 node metastases primary gastric lymphomas, mostly low‐grade lymphomas mucosa‐associated lymphoid tissue (MALT) type were investigated morphologically immunohistochemically. Both groups showed the same morphological immunohistochemical features: diagnostically important sites infiltration sinuses marginal zones, The tumour cells either medium‐sized or small. cytoplasm stained grey with Giemsa was sometimes rather pale. In...
This phase II trial assessed the toxicity and efficacy of irinotecan plus docetaxel in cisplatin-pretreated oesophageal cancer. Irinotecan 160 mg m−2 65 once every 3 weeks led to severe myelosuppression four patients, all whom experienced neutropenic fever. After amendment this regimen, 24 patients (male/female=18/6; median age=58.5 years; ECOG performance status 0/1/2=9/11/4) with advanced cancer (adenocarcinoma/epidermoid carcinoma=13/11) received 55 25 on days 1, 8 15 a 28-day cycle....
Parathyroid carcinomas and neuroendocrine of the pancreas are rare malignancies in humans. Because their low radio- chemosensibility, they fail to respond conventional therapy. We therefore tested a dendritic cell immunotherapy an attempt control tumour growth two patients. Studies on mice humans have demonstrated potent capacity cells induce specific antitumour immunity. Mature were generated from peripheral blood monocytes presence granulocyte/macrophage colony-stimulating factor,...
Abstract Background Neuroepithelial transforming gene 1 (NET1) mediates tumour invasion and metastasis in a number of cancers, including gastric adenocarcinoma. It is an indicator poor prognosis breast cancer glioma. This study examined NET1 expression its prognostic significance patients with adenocarcinoma the oesophagogastric junction (AOG). Methods was measured by immunohistochemistry tissue microarray, constructed from biobanked collected over 10-year interval, linked to prospectively...
Understanding bone surface curvatures is crucial for the advancement of material design, as these play a significant role in mechanical behavior and functionality structures. Previous studies have demonstrated that curvature distributions could be used to characterize geometry been proposed key parameters biomimetic microstructure design optimization. However, understanding how correlate with properties remains limited. This study hypothesized predict well trabecular bone. To test...
Introduction There is considerable uncertainty about the reproducibility of various instruments used to measure dyspnea, their ability reflect changes in symptoms, whether they accurately patient's experience and if its evolution similar between acute heart failure syndrome patients nonacute patients.URGENT was a prospective multicenter trial designed address these issues.Methods Patients were interviewed within 1 hour first physician evaluation, emergency department or care setting, with...
20651 Background: FN is the most frequent dose-limiting toxicity of myelosuppressive chemotherapy (CT). To date there are few data on costs management in Germany. Methods: Prospective, multicentre, observational, longitudinal study with lymphoma, non small cell lung cancer (NSCLC) and primary breast (PBC) patients (pts). Pts were enrolled consecutively at start 1st or 2nd line (immuno-)CT 4 German hospitals (01/05–12/06). was defined as fever >38ºC ANC <1 × 109/L. If nadir unavailable,...
Introduction Community-acquired pneumonia remains a common condition worldwide.It is associated with significant morbidity and mortality.The aim of this study was to evaluate conditions that could predict poor outcome.Design Retrospective analyse 69 patients admitted the ICU from 1996 2003.Demographic data included age, sex medical history.Etiologic agents, multiorgan dysfunction, nosocomial infections, SAPS II PORT scores were recorded for each patient.For statistical analysis we used t...
The role of dose intensity in the chemotherapy advanced epithelial ovarian cancer appears to be controversial. No significant benefit has been achieved by escalating doses range applicable without cellular support. Obviously all pertinent studies compared suboptimally dosed (e.g. 50-75% standard dose) treatment with schedules using at upper limit recommendations. Although some higher remission rates were higher-dose arm, this did not translate into meaningful prolongation median overall...
Die Behandlung des nicht-kleinzelligen Lungenkarzinoms hat sich im letztes Jahrzehnt von einem sehr allgemeinen Therapieregime basierend auf einer platinhaltigen Kombinationschemotherapie, zu zunehmend personalisierten und zielgerichteten molekularen Therapie weiterentwickelt.
This guideline is a prerequisite for the quality management in treatment of non-Hodgkon-lymphomas patients with relapsed or refractory follicular lymphoma after rituximab therapy and as consolidation first remission following CHOP like using radioimmunotherapy. It based on an interdisciplinary consensus contains background information definitions well specified indications detailed contraindications treatment. Essential topics are requirements institutions performing therapy. For instance,...
Hintergrund: Konjunktivale lymphoide Tumoren zeigen sich lachsfarben mit einer Prädilektion der Fornices. Der Erkrankungsgipfel liegt in 5.–7. Lebensdekade. Hier erfolgt die Falldarstellung eines Patienten (67 Jahre, männl.), seit Ende März 2008 eine Schwellung Bindehaut zunächst einseitig bemerkte. Methoden: Die Erstvorstellung erfolgte am 24.4.2008. Zur Diagnosesicherung wurde Bindehautbiopsie durchgeführt. Anschließend erfolgten ein staging und aufgrund linksseitigen Ellenbogenschwellung...
Hydrogen sulfide is produced endogenously by a variety of enzymes involved in cysteine metabolism.Clinical data indicate that endogenous levels hydrogen are diminished various forms cardiovascular diseases.The aim the current study was to investigate effects supplementation on cardiac function during reperfusion clinically relevant experimental model cardiopulmonary bypass.Twelve anesthetized dogs underwent hypothermic bypass.After 60 minutes arrest, started after application either saline...