Streptococcus mutans is a known pathogen of dental caries and its major cell surface antigens have been widely investigated. Recently, an approximately 120 kDa Cnm protein with binding properties to type I collagen was identified, encoding gene (cnm) cloned sequenced. In the present study, we sequenced cnm from 47 different clinical S. strains found that nucleotide alignment collagen-binding domain well conserved. We devised PCR method for identifying gene, examined prevalence cnm-positive...

ABSTRACT Streptococcus mutans is the major pathogen of dental caries, a biofilm-dependent infectious disease, and occasionally causes infective endocarditis. S. strains have been classified into four serotypes ( c , e f k ). However, little known about population, including clonal relationships among in relation to particular clones that cause systemic diseases. To address this issue, we developed multilocus sequence typing (MLST) scheme for . Eight housekeeping gene fragments were sequenced...

English summary Nor Tannlegeforen Tid. 2025; 135: 10-6. Caries and periodontal/peri-implant diseases are two of the most common oral diseases, and, according to recent definitions, considered non-communicable biofilm-induced . In 1970s, caries periodontal were prevalent across all Nordic countries. However, today, for younger generation individuals, rates very low, whilst gingivitis periodontitis remain in adult populations These dental also affect elderly due longer tooth retention....

Kahta yleisintä suusairautta, kariesta ja parodontaalisairauksia, pidetään uusimpien määritelmien mukaan ei-tarttuvina sairauksina, jotka biofilmi aiheuttaa. Molemmat taudit olivat yleisiä 1970-luvulla kaikissa Pohjoismaissa, mutta nykyään karieksen ilmaantuvuus on nuorilla vähäistä, kun taas ientulehdusta parodontaalisairauksia esiintyy yhä paljon pohjoismaisissa aikuisväestöissä. Näitä sairauksia myös ikääntyneillä, koska hampaat säilyvät pidempään.Karies erityisesti parodontaalisairaudet...

ABSTRACT The production of bacteriocin-like inhibitory substances, mutacins, by mutans streptococci varies among isolates. To find if the degree mutacin activity an isolate was related to its transmission between mother and her child, 19 mothers their 18-month- 3-year-old children were sampled for oral streptococci. In addition, stability studied with isolates from five unrelated 5-year-old in 5- 7-year follow-up studies. A total 145 streptococcal serotyped immunodiffusion, ribotyped, typed...

The aim of the study was to evaluate capability caries‐related salivary tests and a test based on past caries experience (baseline DPS) select persons at high risk for caries. subjects (n = 122) were 12–17 years old beginning study. Caries registered samples taken annually during 3‐study period. 3‐year increment positively correlated baseline DPS (r 0.46, p < 0.001), level mutans streptococci 0.30, 0.001) lactobacilli combined 0.39, negatively buffering capacity saliva =−0.22, 0.05)....

Abstract – A method was developed to facilitate the estimation of S. mutans levels in saliva. Paraffin‐stimulated saliva poured on a special slide coated with mitis‐salivarius‐sucrose agar. Two discs containing bacitracin (5 μg) were placed inoculated and growth density around scored after incubation candle jars at 37°C for 48h. The obtained score values correlated well numbers CFU per 1 ml estimated by conventional using mitis‐salivarius‐bacitracin experimental further tested incubating...

Immunosuppressive drugs and other medications may predispose patients to oral diseases. Data on mucosal health in recipients of liver transplantation (LT) are limited. We, therefore, recruited 84 LT (64 with chronic disease 20 acute failure) for clinical examinations a cross-sectional, case-control study. Their had been clinically examined before transplantation. The prevalence lesions (OMLs) was assessed groups different etiologies immunosuppressive medications, these were compared controls...

The clonal diversity and colonization pattern of mutans streptococci within an individual were studied by using a total 50 tooth site samples obtained from seven 3– to 7–year–old children. Five children contributed saliva samples. From the 7 subjects, 90, 74, 81, 53, 83, 103, 114 isolates (a 598) representing <i>Streptococcus mutans</i> sobrinus</i> included for arbitrarily primed polymerase chain reaction (AP–PCR) fingerprinting. harbored one four different AP–PCR types...

The susceptibilities of 379 clinical mutans streptococcal isolates to chlorhexidine (CHX) were tested by agar dilution according the standards National Committee for Clinical Laboratory Standards. Isolates obtained from saliva samples 34 young mothers who had high or moderate salivary levels streptococci at baseline. Samples collected on three occasions, before childbirth, when each child was 6 months old, and 1 year later. Of these isolates, 50% inhibited microgram CHX per ml, 90% 2.0...

Abstract – In order to find out if it is possible prevent caries and gingivitis by periodical use of chlorhexidine‐fluoride mouthrinses with or without strontium, what effects they have on salivary mutans streptococci lactobacilli counts, a total 243 schoolchildren aged 11 yr high DMFS scores were randomly divided into four groups. One group (C) served as basic control. Subjects in the second (GXF) rinsed their mouths twice day every third week rinsing solution containing 0.05% chlorhexidine...

Recipients of liver transplantation (LT) receive lifelong immunosuppression, which causes side effects. We investigated self-reported oral symptoms and associated risk factors with the following hypothesis: signs would differ between LT recipients different etiology groups also a control population. Eighty-four (64 chronic disease 20 acute disease) were recruited for clinical salivary examinations (median follow-up = 5.7 years). A structured questionnaire was used to record subjective...

Streptococcus mutans, a major pathogen of dental caries and infective endocarditis, is classified into serotypes c, e, f, k, with serotype k strains recently reported to be frequently detected in persons endocarditis. Thus, we hypothesized that common properties associated endocarditis are present those strains. Fifty-six oral S. mutans strains, including 11 were analyzed. Western blotting analysis revealed expression the 3 types glucosyltransferases all while approximately 190-kDa...

The levels of salivary Streptococcus mutans and lactobacilli caries experience were studied in 113 teenagers 163 adults. study population consisted 82 mother-child 73 father-child pairs. number decayed, missing, filled tooth surfaces (DMFS) was eightfold higher adults than (56.4 ± 22.8 vs. 7.3 6.7). percentage distribution the level S. approximately same both groups. mean DMFS increased with increasing lactobacilli, correlation being highly significant There a indices pairs (r = 0.364), but...

Salivary biomarkers have been linked to various systemic diseases. We examined the association between salivary biomarkers, periodontal health, and microbial burden in liver transplant (LT) recipients with without diabetes, after transplantation. hypothesized that diabetic would exhibit impaired parameters. This study included 84 adults who received an LT 2000 2006 Finland. Dental treatment preceded The were re-examined, on average, six years later. evaluated a battery of microbiota,...

The growth of Streptococcus mutans was followed for three years in 24 healthy 12‐17 year‐old children, who were selected the study on basis undetectable levels salivary S. mutans. saliva samples cultured by a dip‐slide method based mitis‐salivarius agar supplemented with sucrose and bacitracin. At final occasion, additional examination plaque 10 children using TSY20B performed. During 3‐year period, found from 15 one or more 4 test occasions, suggesting that most ‘S. negative individuals’...