A5098685387- Radiomics and Machine Learning in Medical Imaging
- Nanoplatforms for cancer theranostics
- Glioma Diagnosis and Treatment
- Extracellular vesicles in disease
Hospital Universitario La Paz
2024
Abstract Glioblastoma (GB) is a devastating tumor of the central nervous system characterized by poor prognosis. One best-established predictive biomarker in IDH-wildtype GB O6-methylguanine-DNA methyltransferase (MGMT) methylation (mMGMT), which associated with improved treatment response and survival. However, current efforts to monitor patients through mMGMT detection have proven unsuccessful. Small extracellular vesicles (sEVs) hold potential as key element that could revolutionize...
Despite advancements in personalized cancer therapies, platinum-based chemotherapy remains the cornerstone for treating solid tumors, including Non-Small Cell Lung Cancer (NSCLC). The integration of novel immunotherapies with platinum compounds has shown promising outcomes treatment advanced disease. However, a significant proportion patients experience therapeutic failure due to innate or acquired resistance. Thus, identifying molecular profiles and biomarkers monitor patient progress...