A5017986976- Head and Neck Cancer Studies
- Viral-associated cancers and disorders
- Asian Culture and Media Studies
- RNA modifications and cancer
- Advanced Radiotherapy Techniques
- Ferroptosis and cancer prognosis
- Glioma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Cancer Immunotherapy and Biomarkers
- Head and Neck Surgical Oncology
- Nausea and vomiting management
- Pathogenesis and Treatment of Hiccups
- Polyomavirus and related diseases
- Chemotherapy-related skin toxicity
Huazhong University of Science and Technology
2022-2025
Hubei Cancer Hospital
2022-2025
Ondansetron orally soluble pellicle can serve as an alternative option for preventing nausea and vomiting in patients who receive chemotherapy. However, there is a lack of clinical evidence regarding ondansetron. This study aimed to explore the efficacy safety ondansetron with malignant tumours received chemotherapy drugs moderate-to-high emetic risk. In total, 163 24 mg via pellicles at 30 min before (8 each time three consecutive administrations). The incidence rates days after were...
Abstract Background and Purpose The optimal number of cycles induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (LANPC) remains unresolved. This study aimed to quantitatively assess the changes gross tumor volumes (GTVs) select most IC cycles. Methods We analyzed 54 patients who received a three‐cycle before commencing radiotherapy, with nodal responses assessed by CT scan after each cycle. nasopharynx primary lesion (GTV_T), involved retropharyngeal lymph node...
Immune checkpoint blockade (ICB) therapies have redefined human cancer treatment, including for head and neck squamous cell carcinoma (HNSCC). However, clinical responses to various immune inhibitors are often accompanied by immune-related adverse events (irAEs). Therefore, it is crucial obtain a comprehensive understanding of the association between different tumor microenvironments (TMEs) immunotherapeutic response.The research data were obtained from The Cancer Genome Atlas (TCGA)...
Background: Because the vast majority of nasopharyngeal carcinoma (NPC) in Chinese patients is a direct result Epstein–Barr virus (EBV) infection, there dearth data for EBV-negative this population. This multicenter study sought to examine clinical characteristics and compare long-term outcomes with propensity-matched (1:1.5) EBV-positive cohort. Methods: NPC known EBV status from four hospitals were collated (2013–2021). A logistic regression model was conducted evaluate relationship...
Background: The role of Forkhead Box D2 (FOXD2) in head and neck squamous cell carcinoma (HNSC) has never been studied. Object: Our object was to explore the FOXD2 HNSC. Methods: Clinical data for patients with HNSC obtained from TCGA. study examined atypical expression both pan-cancer, along its diagnostic prognostic implications, as well association between clinical characteristics, immune infiltration, checkpoint genes, MSI. Gene set enrichment analysis (GESA) used investigate potential...
Abstract Background: Because the vast majority of nasopharyngeal carcinoma (NPC) in Chinese patients is a direct result Epstein–Barr virus (EBV) infection, there dearth data for EBV-negative this population. This multicenter study sought to examine clinical characteristics population and compare long-term outcomes with propensity-matched (1:1.5) EBV-positive cohort. Methods: NPC known EBV status from four hospitals were collated (2013-2021). A logisticregression model was conducted evaluate...
Abstract Background Because the vast majority of nasopharyngeal carcinoma (NPC) in Chinese patients is a direct result Epstein–Barr virus (EBV) infection, there dearth data for EBV-negative this population. This multicenter study sought to examine clinical characteristics population and compare long-term outcomes with propensity-matched (1:1.5) EBV-positive cohort. Methods NPC known EBV status from four hospitals were collated (2013–2021). A logistic regression model was conducted evaluate...