- Advanced MRI Techniques and Applications
- Reproductive System and Pregnancy
- Retinal Development and Disorders
- Endometriosis Research and Treatment
- Gut microbiota and health
- Single-cell and spatial transcriptomics
- Cell Image Analysis Techniques
Allen Institute for Brain Science
2024
Southern California University for Professional Studies
2024
University of Southern California
2024
Allen Institute
2024
The mammalian cortex is composed of a highly diverse set cell types and develops through series temporally regulated events that build out the type circuit foundation for cortical function. mechanisms underlying development different remain elusive. Single-cell transcriptomics provides capacity to systematically study across entire temporal range development. Here, we present comprehensive high-resolution transcriptomic epigenomic atlas developing mouse visual cortex. was built from...
Decline in ovarian function with age not only affects fertility but is also linked to a higher risk of age-related diseases women ( e.g . osteoporosis, dementia). Intriguingly, earlier menopause shorter lifespan; however, the underlying molecular mechanisms aging are well understood. Recent evidence suggests gut microbiota may influence health. In this study, we characterized associated microbial profiles mice and investigated effect microbiome from young estropausal female on health through...