Afoma Onyechi

ORCID: 0009-0004-1979-8806
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About
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Research Areas
  • Blood groups and transfusion
  • Palliative Care and End-of-Life Issues
  • Viral-associated cancers and disorders
  • Acute Myeloid Leukemia Research
  • Histiocytic Disorders and Treatments
  • Frailty in Older Adults
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer survivorship and care
  • Blood disorders and treatments
  • Antioxidant Activity and Oxidative Stress
  • Prostate Cancer Treatment and Research
  • Platelet Disorders and Treatments
  • Neurological and metabolic disorders
  • Polyomavirus and related diseases
  • Neutropenia and Cancer Infections
  • Erythrocyte Function and Pathophysiology
  • Renal and related cancers
  • Pancreatic and Hepatic Oncology Research
  • Patient Dignity and Privacy
  • Bladder and Urothelial Cancer Treatments
  • Colorectal Cancer Treatments and Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • PARP inhibition in cancer therapy
  • Retinoids in leukemia and cellular processes
  • Economic and Financial Impacts of Cancer

St. Mary's Hospital
2022-2024

St Mary's Hospital
2022-2024

St. Mary's Health Center
2023-2024

St. Mary's Medical Center
2022-2024

Saint Louis University Hospital
2023

Abbott Northwestern Hospital
2023

Acute promyelocytic leukemia (APL) is associated with an elevated risk of developing disseminated intravascular coagulation (DIC). The purpose this study was to assess the outcomes hospitalizations related DIC in APL and their impact on healthcare.

10.4274/tjh.galenos.2024.2023.0479 article EN cc-by-nc-nd Turkish Journal of Hematology 2024-02-20

The objective of this study was to examine the characteristics and utilization patterns palliative care among kidney cancer patients using a large-scale representative population-based sample. We retrospectively analyzed National Inpatient Sample hospitalization data from January 2020 December explore disparities in delivering deceased assess its impact on healthcare usage, focusing hospital costs length stay (LoS). used ICD-10 CM codes (International Classification Diseases-classifying...

10.15586/jkcvhl.v11i1.314 article EN cc-by Journal of Kidney Cancer and VHL 2024-02-20

e23054 Background: The impact of Hospital frailty risk score on outcomes in hospitalized patients with prostate cancer has not been previously studied. This research aimed to examine the association between and outcomes. Methods: retrospective study utilized hospitalization data from National Inpatient Sample (NIS) January 1, 2020, December 31, 2020. Data a primary or secondary discharge diagnosis (ICD10-CM codes C61.0, D07.5, Z85.46) were obtained. objective was evaluate correlation cancer....

10.1200/jco.2024.42.16_suppl.e23054 article EN Journal of Clinical Oncology 2024-06-01

Abstract Objective: This study aims to explore the characteristics of receiving palliative care and patterns utilization among breast cancer patients using a large-scale representative population-based sample. Methods: A retrospective analysis was performed on hospitalization data obtained from National Inpatient Sample (NIS) covering period January 2016 December 2019. The objective investigate disparities associated with provision who had passed away, evaluate its impact healthcare as...

10.1158/1538-7445.sabcs23-po3-10-04 article EN Cancer Research 2024-05-02

Abstract Background Graft‐versus‐host disease (GVHD) is a recognized complication among individuals undergoing bone marrow transplantation (BMT). There requirement for supplementary data regarding the in‐patient outcomes of GVHD in who have undergone BMT. Our analysis seeks to assess healthcare burden and associated with hospitalized patients Method In this retrospective study, we used from National Inpatient Sample (NIS) database spanning 2016 2019. Utilizing ICD‐10 codes, distinguished...

10.1111/ejh.14281 article EN cc-by-nc-nd European Journal Of Haematology 2024-08-12

Multiple myeloma (MM) is a relatively uncommon neoplastic proliferation of monoclonal plasma cells. Common manifestations are related to infiltration cells into bones and other organs, causing an increased total serum protein concentration, hypercalcemia, kidney injury, anemia. The most common type MM IgG Kappa, the second IgA subtype. Hyperviscosity (HVS) rare presentation management includes prompt plasmapheresis, resulting in significant reduction viscosity symptomatic relief. We present...

10.55729/2000-9666.1397 article EN cc-by-nc Journal of Community Hospital Internal Medicine Perspectives 2024-09-09

Introduction: Skin cancer is one of the most prevalent forms worldwide, with a significant increase in recent decades. Real-time and accurate detection can reduce burdens invasive treatments. The advent Artificial Intelligence (AI) Machine learning (ML) has introduced multiple tools to aid early detection, categorizing dermatological images proving especially valuable regions shortage specialists. However, adoption these AI-based requires consideration efficacy, safety, ethical implications....

10.36348/gajms.2024.v06i05.009 article EN Global Academic Journal of Medical Sciences 2024-10-23

Castleman disease (CD) is a rare lymphoproliferative disorder encompassing spectrum of conditions with distinct histopathological findings and varied clinical presentations. Diagnostic challenges are often encountered due to overlapping features other malignancies, infections, autoimmune disorders. Idiopathic multicentric (iMCD) subtype CD, characterized by generalized lymphadenopathy, polyclonal lymphoproliferation, systemic inflammation, cytokine storm that can be life-threatening. Here,...

10.7759/cureus.73156 article EN Cureus 2024-11-06

Acute intermittent porphyria (AIP) is a rare disease that arises due to deficiency of the biosynthetic enzyme porphobilinogen deaminase (PBGD) involved in heme synthesis. attacks can present with abdominal pain and neurological symptoms, although vague nature. Recurrent hospitalizations for idiopathic should warrant investigation AIP, Posterior reversible encephalopathy (PRES) visual disturbances seizure-like activity be, rarely associated AIP. It noteworthy know antiepileptic medication...

10.55729/2000-9666.1232 article EN cc-by-nc Journal of Community Hospital Internal Medicine Perspectives 2023-09-02

5-fluorouracil (5-FU) is a well-known chemotherapeutic agent used for the treatment of colon cancer and other solid malignancies. Dihydropyrimidine dehydrogenase (DPD) an enzyme that catalyzes 5-FU, if patient deficient, such as through gene mutation, they can be predisposed to severe toxicity. Although 5-FU-induced neurotoxicity extremely rare, it fatal. We report case 5-FU in 56-year-old male with keratinizing squamous cell carcinoma anal canal on concurrent chemoradiation therapy...

10.7759/cureus.49898 article EN Cureus 2023-12-04

Cyclic thrombocytopenia (CTP) is a very rare hematological disorder that characterized by periodic fluctuations in platelet counts. Diagnosis generally delayed due to its similarity with immune (ITP). The pathophysiology unknown and there are currently no guidelines for management. Many patients usually treated ITP initially prior diagnosis. We describe 67-year-old female history of multiple episodes transient who presented the hospital another episode thrombocytopenia. Her workup including...

10.7759/cureus.22525 article EN Cureus 2022-02-23

e17060 Background: PARP inhibitors effectively treat several solid tumors, regardless of the presence BRCA mutations. Patients with castration-resistant metastatic prostate cancer become refractory to androgen deprivation therapy. were recently approved for use in cancer, and have opened new avenues treatment research. Methods: We systematically searched multiple databases using pre-specified search terms. included only phase III RCTs comparing versus standard care patients biopsy-proven...

10.1200/jco.2023.41.16_suppl.e17060 article EN Journal of Clinical Oncology 2023-06-01

Drug-induced immune hemolytic anemia (DIIHA) is a relatively uncommon cause of anemia, and its diagnosis can be challenging. Although beta-lactam antimicrobial agents are often associated with DIIHA, any medication potentially it. We describe patient presenting yellow skin discoloration orange-colored urine after starting metaxalone for treatment lumbosacral sprain. Laboratory studies were consistent warm anemia. Symptoms improved remarkably discontinuation metaxalone, coupled initiation...

10.55729/2000-9666.1236 article EN cc-by-nc Journal of Community Hospital Internal Medicine Perspectives 2023-09-02
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