A5101608284- Multiple and Secondary Primary Cancers
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Treatments and Studies
- Health Systems, Economic Evaluations, Quality of Life
- Colorectal and Anal Carcinomas
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Colorectal Cancer Surgical Treatments
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- COVID-19 Clinical Research Studies
- Sympathectomy and Hyperhidrosis Treatments
- Cardiac Structural Anomalies and Repair
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Ferroptosis and cancer prognosis
- Airway Management and Intubation Techniques
- Parkinson's Disease and Spinal Disorders
- Parkinson's Disease Mechanisms and Treatments
- Ubiquitin and proteasome pathways
- Coronary Artery Anomalies
- Cardiovascular Syncope and Autonomic Disorders
- Testicular diseases and treatments
- Cardiovascular Issues in Pregnancy
Hospital da Luz
2020-2024
A avaliação rápida e a intervenção em casos de acidente vascular cerebral (AVC) agudo são essenciais para melhorar os desfechos clínicos, dada gravidade alta incidência dessa condição, que é segunda principal causa morte global incapacidade permanente. O AVC isquêmico, causado pela obstrução do fluxo sanguíneo cerebral, o hemorrágico, decorrente da ruptura vasos sanguíneos, demandam diagnósticos precisos intervenções específicas. Diante disso, este estudo tem como objetivo analisar...
A retinopatia diabética (RD) é uma complicação ocular significativa do diabetes mellitus (DM), caracterizada por alterações microvasculares na retina que podem levar à perda visual e, em casos extremos, cegueira. prevalência da tem aumentado globalmente, refletindo a crescente incidência de mellitus, afeta milhões pessoas todo o mundo. As estratégias prevenção são fundamentais para diminuir impacto dessa doença sobre saúde pública. identificação precoce com e manejo adequado essenciais...
Guidelines recommend regional lymphadenectomy with a lymph node yield (LNY) of at least 12 nodes (LN) for adequate colon cancer (CC) staging. LNY ≥22LN may improve survival, especially in right-sided CC [Lee et al., Surg Oncol, 27(3), 2018]. This multicentric retrospective cohort study evaluated the impact and tumor laterality on staging survival.Patients stage I-III that underwent surgery from 2012 to 2018 were grouped according LNY: <22 ≥ 22. Primary outcomes LN positivity (N+ rate)...
96 Background: Previous data on surgery for colorectal cancer (CRC) liver metastases (CRLM) documented improvement in overall survival (OS) and low perioperative mortality, but patient (pt) selection requires complex multidisciplinary work. Predictive scores such as the Comprehensive Evaluation of Relapse Risk (CERR) estimate relapse risk after help pre-operative decision. Objectives: This study aims to evaluate OS progression-free (PFS) a population pts who had CRLM, analyse outcomes by...
Patients with metastatic HER2-positive breast cancer have multiple therapeutic options. However, most are not studied in the renal replacement therapy (RRT) setting. We report use of Phesgo® (subcutaneous fixed-dose combination trastuzumab and pertuzumab) combined exemestane as a first-line treatment hemodialysis patient comorbidities. Partial response was attained, disease progression after 8 months without evidence significant toxicity. This case is, to our knowledge, first published...
This study aimed to characterize the employment status and work-related conditions of patients with advanced breast cancer (ABC) in Portugal quantify productivity costs premature abandonment work market while evaluating strategies promote employment. The analysis was based on a cumulative incidence model for estimation ABC prevalence cross-sectional characterizing ABC. conducted Portuguese hospitals, between Nov2021-Dec2022 included diagnosed at least 6 months, aged 66 or less consenting...
Abstract Background Liquid biopsy (LB) is a non-invasive tool to evaluate the heterogeneity of tumors. Since RAS mutations (RAS-mut) play major role in resistance antiepidermal growth factor receptor inhibitors (EGFR) monoclonal antibodies (Mabs), serial monitoring RAS-mut with LB may be useful guide treatment. The main aim this study was prognostic value loss (NeoRAS-wt) LB, during treatment metastatic colorectal cancer (mCRC). Methods A retrospective conducted on patients mCRC between...
Abstract At the time of first wave COVID-19 pandemic cancer patients were considered to be at high risk serious illness and had a higher exposure since they needed frequent non- deferrable hospital visits. Serologic tests not routinely used seroprevalence in this population was unknown. A single-center cross-sectional study developed determine anti- SARS-CoV-2 antibodies (Abs) undergoing systemic antineoplastic treatment. One hundred consecutively recruited two-week period (6th 20th May,...
At the time of first wave COVID-19 pandemic, patients with cancer were considered to be at high risk serious illness and had a higher exposure since they needed frequent nondeferrable hospital visits. Serological tests not routinely used, seroprevalence in this population was unknown. A single-center, cross-sectional study developed determine anti-SARS-CoV-2 antibodies (Abs) undergoing systemic antineoplastic treatment. One hundred consecutively recruited two-week period (6th-20th May 2020),...