A5111174764- Hepatitis B Virus Studies
- Cytokine Signaling Pathways and Interactions
- Psoriasis: Treatment and Pathogenesis
- Liver Disease Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- NF-κB Signaling Pathways
- Immune Response and Inflammation
- Cancer-related Molecular Pathways
- Pelvic and Acetabular Injuries
- Alcohol Consumption and Health Effects
- Mycobacterium research and diagnosis
- Skin Protection and Aging
- Circular RNAs in diseases
- Synthesis and Reactivity of Heterocycles
- Virology and Viral Diseases
- Autophagy in Disease and Therapy
- Traditional Chinese Medicine Studies
- Mosquito-borne diseases and control
- Dermatology and Skin Diseases
- Nausea and vomiting management
- Microtubule and mitosis dynamics
- Heme Oxygenase-1 and Carbon Monoxide
Dalian Jiaotong University
2025
Xiangya Hospital Central South University
2017-2025
Central South University
2017-2025
Guangzhou Medical University
2025
Tianjin First Center Hospital
2022-2025
Tianjin Medical University
2022-2025
Chengdu Normal University
2023
Nanjing University of Chinese Medicine
2023
Shenyang Pharmaceutical University
2020
Qilu Hospital of Shandong University
2016-2019
Metal plates and screws are widely used as internal fixations in the treatment of ankle fracture. However, there many disadvantages such "stress shielding" effect need for secondary surgical removal, which potentially affected blood supply around fracture site. In recent years, studies confirmed that biodegradable high purity magnesium (Mg) exhibited sufficient mechanical strength with adequate degradation rate effective bone healing, avoiding implant removal operations. We conducted a...
Long noncoding RNAs (lncRNAs) serve important roles in the biology of autoimmune diseases and immune‑associated disorders. To identify lncRNAs specifically associated with psoriasis, expression from biopsies obtained patients psoriasis were compared samples healthy volunteers using a microarray. Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) was performed to detect 10 identified dysregulated lncRNAs. Cis‑ trans‑regulated target genes predicted. The results microarray...
The objective of this study was to investigate the mechanism by which miR-146a-5p mediated autophagy and hepatitis B virus (HBV) replication. Quantitative real-time polymerase chain reaction (qRT-PCR) used determine mRNA expression levels X-linked inhibitor apoptosis (XIAP) HBV DNA RNA. protein XIAP, IκB-α, murine double minute 2 oncoprotein (MDM2) p53, phosphorylation p65, conversion light 3 (LC3)-I LC3-II were detected Western blotting. HBV-related pro-inflammatory cytokines, serum markers...
Background Periodontitis is a typical oral disease. Polymorphonuclear neutrophils (PMNs) are crucial immune cells in periodontal tissues, relating to infection, inflammation, and innate immunity. We herein aimed explore important periodontitis PMN related genes. Methods control samples were downloaded from Gene Expression Omnibus database, including GSE173082 (methylation data, n=72), GSE10334 (n=127), GSE43525 (n=23), GSE16134 (n=134). Differential expression analysis differential...
Abstract Background Hepatitis B virus (HBV) remains a major cause of chronic hepatitis and hepatocellular carcinoma, miRNAs play important roles in HBV pathogenesis. Our previous study has shown that miR-328-3p is upregulated HBV-infected patients serves as potent predictor for the prognosis HBV-related liver failure. Methods Here, role modulating cell injury cells THLE-2 was investigated detail. MiR-328-3p expression examined using qRT-PCR. The levels pro-inflammatory cytokines were...
PurposeThis investigation was conceived to engineer and appraise a pioneering clinical nomogram, crafted bridge the extant chasm in literature regarding postoperative risk stratification for deep vein thrombosis (DVT) aftermath of lower extremity orthopedic procedures. This novel tool offers sophisticated discerning algorithm prediction, heretofore unmet by existing methodologies.MethodsIn this retrospective observational study, records hospitalized patients who underwent surgery were...
Objective: To explore the clinical efficacy of intravitreal injection conbercept in combination with retinal laser photocoagulation treatment diabetic macular edema.
 Methods: Ninety patients edema were selected and grouped into an observation group a control using random number table, 45 (45 eyes) each group. The was given photocoagulation, while Conbercept on basis panretinal photocoagulation. Best Corrected Visual Acuity (BCVA), thickness nerve fibre layer (RNFL) measured through...
Objective: To investigate the expression of microRNA-30a (miR-30a) in hepatocellular carcinoma (HCC) and related molecular mechanisms regulating HCC cell proliferation. Methods: A total 30 pairs adjacent tissue samples were collected, quantitative real-time PCR Western blot used to measure mRNA protein forkhead-box A1 (FOXA1). Methyl thiazolyl tetrazolium (MTT) assay was evaluate proliferation cells, luciferase reporter gene performed verify target relationship between miR-30a FOXA1, MTT...
Background Dissociative anxiety disorder in student group is a common mental the learning process of students. When students are separated from their attachment objects, they will have extremely strong resistance psychology, which lead to excessive dissociative anxiety. more abnormal behaviors and emotions life study. How alleviate students’ has become focus current education research. Subjects Methods In this study, 68 were diagnosed as school randomly divided into experimental control...
Abstract Aims The purpose of this paper is to study the effect isosteviol (ISV) on mice with hepatic ischemia and reperfusion(I/R) injury further investigate its underlying mechanism. Methods blood vessels supplying left/middle lobe liver in were clamped cause for 1h, then conduct reperfusion 6 h. ISV or saline was injected intraperitoneally after reperfusion. expression tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6 IL-10 serum tissues evaluated by ELISA qRT-PCR. infiltration...
Long-term hepatitis B virus (HBV) infection can cause recurrent inflammation in the liver, and then develop into liver fibrosis, cirrhosis, cancer. The hepatic pathological change is one of important criteria for guiding antiviral therapy patients with chronic (CHB). Due to limitations biopsy, it necessary find valuable non-invasive indicators evaluate changes CHB guide therapy. This study aims analyze clinical characteristics different patients, explore factors influnencing degree fibrosis...
Aim: To evaluate the efficacy of dexmedetomidine in analgesia contin-uous infraclavicular brachial plexus block after elbow arthrolysis. Methods: Sixty patients who received unilateral arthrolysis and met inclusion criteria were randomly divided into 2 groups (n = 30): + ropivacaine group (group D) R). The formulation analgesic pump was 0.2% 240 mL ug/kg D R group. VAS scores at rest, 4 h (T1), 8 (T2), 12 (T3), 24 (T4), 36 (T5) 48 (T6) operation recorded, NRS during functional exercise...