A5072228425- Catalytic C–H Functionalization Methods
- Synthesis and Catalytic Reactions
- Sulfur-Based Synthesis Techniques
- Cyclopropane Reaction Mechanisms
- Oxidative Organic Chemistry Reactions
- Multicomponent Synthesis of Heterocycles
- Graphene research and applications
- Quinazolinone synthesis and applications
- Synthesis and pharmacology of benzodiazepine derivatives
- Radical Photochemical Reactions
- Environmental Sustainability and Technology
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis and Biological Activity
- Metal-Organic Frameworks: Synthesis and Applications
- Synthesis of heterocyclic compounds
- Energy, Environment, Economic Growth
- Arctic and Russian Policy Studies
- Energetic Materials and Combustion
- Asymmetric Synthesis and Catalysis
- Fluorine in Organic Chemistry
- Chemical Synthesis and Reactions
Tianjin University of Science and Technology
2024-2025
Jimei University
2024
Gannan Normal University
2022-2024
North University of China
2024
A copper-promoted aerobic oxidative [3+2] cycloaddition reaction for the synthesis of various substituted pyrazoles from N,N-disubstituted hydrazines with alkynoates in presence bases is developed. This work involves a direct C(sp3)-H functionalization and formation new C-C/C-N bonds. In this strategy, inexpensive easily available Cu2O serves as promoter air acts green oxidant. The exhibits advantages high atom step economy, regioselectivity, easy operation.
Here a facile and efficient [2+3] [3+3] annulation of bisnucleophiles have been developed, affording various methylenetetrahydrofuran spirooxindole methylenetetrahydropyrano[2,3‐c]pyrazoles derivatves under mild reaction conditions. This method provides alternative strategies for the cconstruction functionalized oxacyclic products in moderate to good yields. In addition, gram‐scale synthesis transformations were performed examine practicability this methodology.
A facile and efficient copper-catalyzed domino-double annulation strategy was developed from easily accessible o-aminobenzamides 2-iodoisothiocyanates, which affords a direct pathway for the synthesis of tetracyclic fused 12H-benzo[4,5]thiazolo[2,3-b]quinazolin-12-ones in moderate to good yields without addition ligands, bases, external oxidants. The reaction involves C–N bond cleavage formation C–N/C–S one step with advantages using an inexpensive copper catalyst easy operation. Mechanistic...
A visible-light-photoredox-catalyzed intermolecular three-component aminotrifluoromethylation of styrenes with phenylhydrazines and Togni's reagents/fluoroalkyl iodides was developed.
A facile and efficient catalyst-/metal-/oxidant-free DBU-promoted deaminative thiolation reaction of 1H-benzo[d]imidazol-2-amines benzo[d]oxazol-2-amines has been developed at room temperature conditions in a one-pot protocol. This practical three-component strategy represents novel environmentally friendly pathway toward the straightforward synthesis various 2-thio-1H-benzo[d]imidazoles 2-thiobenzo[d]oxazoles using carbon disulfide as sulfur source through C-N bond cleavage C-S formation...
A sequential multi-component reaction of aldehydes and aryl hydrazines for the synthesis N' , -diaryl acylhydrazines with high regioselectivity has been achieved via an aerobic copper-catalyzed process.
In this study, a series of metal–organic framework-199 (MOF-199) products were prepared with copper (Cu) as the metal center and trimesic acid organic ligand. The morphological changes MOF-199 under different preparation conditions its application in catalytic thermal decomposition hexahydro-1,3,5-trinitro-s-triazine (RDX) studied. compared by scanning electron microscopy (SEM), crystal structures analyzed X-ray diffraction effects characteristics on behavior RDX studied differential...
Scientific and technological innovation ecological progress are important forces for China’s high-quality development. Nevertheless, the current body of research seldom explores mutual dependence evolutionary patterns two regional systems when considering both historical future perspectives. This paper aims to enhance theoretical framework by focusing on coastal region China. It analyzes predicts co-evolution space–time distribution process constructing a coupled model gray prediction model....
Abstract Metal‐free [2+2+1] three‐component cascade annulations for the one‐pot synthesis of multiply substituted 3‐cyano‐thiophenes from 3‐oxo‐nitriles, enones and elemental sulfur are described. This DBU‐promoted protocol features good functional group tolerance, provides high value in moderate to yields under simple reaction conditions. approach also enables late‐stage modifications structurally complex bioactive molecules drugs, which exhibits potential applications medicinal chemistry.
Abstract Here a base‐mediated formal [2+4] annulation of 3‐hydroxyoxindoles with 1,2‐bis(bromomethyl)benzene have been accomplished, affording spirooxindole‐fused oxacycles in good yields. This protocol features great functional group tolerance mild reaction conditions. Gram‐scale synthesis and further transformation also demonstrated.
Isochroman is one of the powerful scaffolds which demonstrated various important biologically activities. Herein we represented novel and versatile method for synthesis valuable isochroman spiropyrazolones difunctional peroxides pyrazolones via [1+5] annulation. This process represents a spiroisocchroman protocol featured by good functional group compatibility, mild conditions readily available substrates.