A5014860610- Neuroinflammation and Neurodegeneration Mechanisms
- Immune cells in cancer
- Single-cell and spatial transcriptomics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Sichuan University
2024
West China Hospital of Sichuan University
2024
Abstract Objective Abundant neutrophils have been identified in both ruptured and unruptured intracranial aneurysm (IA) domes, with their function clinical implication being poorly characterized. Materials Methods We employed single‐cell RNA sequencing (scRNA‐Seq) datasets of human murine model, external bulk mRNA to thoroughly explore the features functional heterogeneous infiltrating IA dome. Results found that dome contain a substantial population neutrophils, characterized by FCGR3B ,...
Intracranial aneurysm (IA) is common and occasionally results in life-threatening hemorrhagic strokes. However, the cell architecture inflammation IA dome remain less understood.
微卫星 DNA 分析证明异种克隆大熊猫重构胚的核 来自大熊猫供体