A5061259992- FOXO transcription factor regulation
- Advancements in Battery Materials
- Advanced Battery Materials and Technologies
- Advanced Battery Technologies Research
- Bioactive Compounds and Antitumor Agents
- Cancer therapeutics and mechanisms
- X-ray Diffraction in Crystallography
- RNA modifications and cancer
- Crystallization and Solubility Studies
- Synthesis and biological activity
- Lung Cancer Treatments and Mutations
- Heat shock proteins research
- Computational Drug Discovery Methods
- Boron and Carbon Nanomaterials Research
- PARP inhibition in cancer therapy
- Mitochondrial Function and Pathology
- Magnesium Oxide Properties and Applications
- Intensive Care Unit Cognitive Disorders
- Cellular transport and secretion
- Electrospun Nanofibers in Biomedical Applications
- MXene and MAX Phase Materials
- Cancer Research and Treatments
- Microbial Fuel Cells and Bioremediation
- Layered Double Hydroxides Synthesis and Applications
- Plant Molecular Biology Research
Second Affiliated Hospital of Nanchang University
2023-2024
Nanchang University
2023-2024
Qingdao University of Science and Technology
2020-2024
Qingdao Institute of Bioenergy and Bioprocess Technology
2020-2024
Qinghai New Energy (China)
2024
Chongqing University of Technology
2022-2023
Education Department of Jiangxi Province
2023
The University of Texas Southwestern Medical Center
2011-2018
Sichuan Research Center of New Materials
2017-2018
Konka (China)
2017-2018
Abstract Traditional lithium salts are difficult to meet practical application demand of metal batteries (LMBs) under high voltages and temperatures. LiPF 6 , as the most commonly used salt, still suffers from notorious moisture sensitivity inferior thermal stability those conditions. Here, we synthesize a salt perfluoropinacolatoborate (LiFPB) comprising highly‐fluorinated borate functional groups address above issues. It is demonstrated that LiFPB shows superior electrochemical without any...
Formulating electrolytes is very powerful in protecting lithium (Li) anode from severe Li dendrites growth and pulverization. Herein, by a simple one-step one-pot method, we innovatively synthesize highly fluorinated (8-CF3) aluminum (Al)-centered salt of perfluoropinacolatoaluminate (LiFPA). The as-formulated LiFPA-based enable practical Li/LiCoO2 (areal capacity 1.98 mAh cm–2) Li/LiNi0.6Co0.2Mn0.2O2 3.5 metal batteries (LMBs) with good cycling stability. On the one hand, LiFPA can reduce...
Configuration-dependent electrochemical performances of three types recently synthesized borophenes as non-lithium-ion batteries anode materials have been determined based on density functional theory.
Abstract Magnesium (Mg) metal anode is a highly desirable candidate among various high energy density anodes, possessing higher volumetric capacity and better safety characteristic compared to lithium metal. However, most Mg salts in conventional electrolytes easily react with form blocking layers, leading inferior reversibility of plating/stripping. Here, stable 2+ ‐conducting solid electrolyte interphase (SEI) successfully constructed on by regulating the molecular‐orbital‐energy‐level...
Background Delirium significantly contributes to both mortality and morbidity among hospitalized older adults. Furthermore, delirium leads escalated healthcare expenditures, extended hospital stays, enduring cognitive deterioration, all of which are acknowledged detrimental outcomes. Nonetheless, the current strategies for predicting managing remain constrained. Our aim was employ Mendelian randomization (MR) investigate potential causal relationship between metabolites delirium, as well...
Abstract Traditional lithium salts are difficult to meet practical application demand of metal batteries (LMBs) under high voltages and temperatures. LiPF 6 , as the most commonly used salt, still suffers from notorious moisture sensitivity inferior thermal stability those conditions. Here, we synthesize a salt perfluoropinacolatoborate (LiFPB) comprising highly‐fluorinated borate functional groups address above issues. It is demonstrated that LiFPB shows superior electrochemical without any...
Heterotrophic nitrification-aerobic denitrification (HN-AD) bacteria are aerobic microorganisms that can remove nitrogen under high-salt conditions, but their performance in practical applications not satisfactory. As a compatible solute, trehalose helps to cope with high salt stress by participating the regulation of cellular osmotic pressure, and plays an important role promoting removal efficiency microbial populations environment. We investigated mechanism exogenous-trehalose-enhanced...
Abstract β-Lapachone (β-lap) is a very unique quinone that can be reduced by two-electron oxidoreductase, NQO1, but unlike most other quinones, its hydroquinone form unstable and spontaneously oxidizes back to β-lap in two steps. This redox cycle occurs futile manner which one mole of generates ∼120 moles superoxide minutes, causing predominately DNA base single strand break damage. results PARP1 hyperactivation programmed necrosis an NQO1-dependent manner. Most solid cancers, such as nearly...
Abstract Pancreatic cancer will be the second leading cause of cancer-related deaths in US by 2020, where 5-year survival is <6%. Current standard care therapies offer little selectivity and high toxicity. Novel, tumor-selective approaches are desperately needed. Nearly 90% pancreatic cancers have elevated levels (10- to 40-fold) NQO1 we recently showed that beta-lapachone (beta-lap) was efficacious against an NQO1-dependent manner (Li et al., Clin. Cancer Res., 2011). Beta-Lap...
<div>Abstract<p>A growing number of studies have demonstrated that cancer development is closely linked to abnormal gene expression, including alterations in the transcriptional activity transcription factors. The Forkhead box class N (FOXN) proteins FOXN1–6 form a highly conserved factors, which been shown recent years be involved regulation malignant progression variety cancers. FOXNs mediate cell proliferation, cell-cycle progression, differentiation, metabolic homeostasis,...
<p>Supplementary Figure 1, 2 and Table 1,2</p>
<p>Supplementary Figure 1</p>
<p>Supplementary Figure 2</p>
<p>Supplementary Figure 1</p>
<p>Supplementary Figure 2</p>