About
Contact & Profiles
A5093394784
Research Areas
- Phosphodiesterase function and regulation
- Peptidase Inhibition and Analysis
- Protease and Inhibitor Mechanisms
- Osteoarthritis Treatment and Mechanisms
- Neuropeptides and Animal Physiology
- Chemical Synthesis and Analysis
- Cell Adhesion Molecules Research
University of Surrey
2023-2024
The proteolytic activity of the enzyme ADAMTS7 was recently shown to enhance progression atherosclerosis, in line with human genetic findings suggesting that has a role pathophysiology coronary heart disease. Targeting active site small molecule inhibitor, therefore, therapeutic potential. Here, we report design and synthesis novel hydroxamate-based arylsulfonamide is potent selective inhibitor.
10.1039/d4md00149d
article
EN
cc-by
RSC Medicinal Chemistry
2024-01-01
10.1007/978-1-0716-3589-6_5
article
EN
Methods in molecular biology
2023-12-01
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