A5073819179- Ovarian cancer diagnosis and treatment
- Intraperitoneal and Appendiceal Malignancies
- Endometrial and Cervical Cancer Treatments
- Colorectal Cancer Surgical Treatments
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Metastasis and carcinoma case studies
- Gynecological conditions and treatments
- Genetic factors in colorectal cancer
- Circular RNAs in diseases
- Colorectal and Anal Carcinomas
- Cancer Immunotherapy and Biomarkers
- Renal cell carcinoma treatment
- Gastrointestinal disorders and treatments
- Immune Cell Function and Interaction
- Gastrointestinal Tumor Research and Treatment
- Urinary and Genital Oncology Studies
- Intestinal and Peritoneal Adhesions
University of Padua
2022-2025
Hospital de Sant Pau
2024
(1) Background: Endometrial carcinoma (EC) classified as no specific molecular profile (NSMP) represents a heterogeneous group with variable prognoses. This retrospective, single-center study aims to further stratify NSMP ECs tailor treatment strategies and improve outcomes. (2) Methods: From 2020 2023, we collected data on 51 patients diagnosed EC following the introduction of profiling at our institution. Patients were retrospectively analyzed for estrogen receptor (ER) status, histotype,...
Background: The Endometriosis Fertility Index (EFI), is a crucial validated surgical tool used for predicting fertility outcomes in women with endometriosis. This study aims to assess the concordance between preoperative clinical and instrumental EFI evaluation (uEFI) score obtained during an exploratory laparoscopy prior surgery (sEFI). Methods: presents preliminary data from broader observational cohort study. Least Function uEFI was calculated using modified version of original by...
We aimed to compare the clinical utility and diagnostic accuracy of ADNEX model, ROMA score, RMI I, IV, as well two serum markers (CA125 HE4) in preoperative discrimination between benign malignant adnexal masses (AMs).
<h3>Introduction/Background</h3> This study aimed to find the incidence of occult malignancy (precursor lesions and cancer) after RRSO in BRCA1/2 carriers due most do not undergo by recommended age. <h3>Methodology</h3> We retrospectively reviewed patients identified as BRCA mutation who underwent at Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, from 1993 2023. Of all patients, we analyzed objective examination, CA 125 values transvaginal ultrasound preoperatively. All cases were...
<h3>Introduction/Background</h3> This video shows a laparoscopic en-bloc resection of the pelvis with rectosigmoid and termino-terminal anastomosis in 75-year-old patient affected by advanced ovarian carcinoma. The was discussed at our tumor board CT scan showing solid pelvic mass (approximately 12x8x8 cm) upper abdominal diaphragmatic disease. findings were later confirmed exploratory laparoscopy when decision made to perform up-front surgery. recruited ULTRA-LAP trial (NCT05862740)...
<h3>Introduction/Background</h3> Ovarian cancer (OC) usually presents at advanced stage. Complete cytoreduction has a major positive effect on survival and primary debulking surgery (PDS) remains the standard treatment for OC patients. When complete is not feasible, neoadjuvant chemotherapy interval (IDS) must be considered. We aimed to compare surgical outcomes rates between (AOC) patients undergoing IDS those PDS. <h3>Methodology</h3> This retrospective single-center observational study...
<h3>Introduction/Background</h3> Ovarian cancer (OC) is the most lethal among gynecological malignancies. Exploratory laparoscopy (EXL) has proven successful in preoperatively assessing disease extent, minimizing unnecessary laparotomies. However, occurrence of port site metastases (PSM) following EXL a common complication insufficiently documented, with reported rates ranging from 16% to 49%. This study focuses on investigating incidence, timing, and outcomes PSM stage III-IV OC patients...
<h3>Introduction/Background</h3> The Chemotherapy Response Score (CRS) has been validated to assess the response and prognosis of high-grade ovarian cancer (HGOC) neoadjuvant chemotherapy (NACT). Similarly, peritoneal index (PCI) before after NACT could quantitatively variation tumor burden in cavity. aim study was evaluate ability PCI predict histopathologic achieve complete cytoreduction at interval debulking surgery (IDS). <h3>Methodology</h3> Thirty-two patients with advanced HGOC who...
<h3>Introduction/Background</h3> Surgery of the mesentery has been reported in other surgical disciplines along with resection dependent bowel segment. In patients ovarian cancer, this technique would imply extensive resection, leading to severe malnutrition and impacting on timely provision chemotherapy. Therefore, a that spares selectively removes disease meso is highly desirable. <h3>Objective</h3> The aim describe technique, assess its feasibility, efficacy, safety performing...
<h3>Introduction/Background</h3> Indication of surgery for ovarian cancer (OC) is often influenced by patients' age, as older individuals are presumed to have lower tolerance radical surgery. However, limited evidence exists on whether the surgical risks outweigh benefits in elderly patients. We aimed compare perioperative complications between patients (EP) and non-elderly (NEP) undergoing OC. <h3>Methodology</h3> This retrospective single-center observational study includes consecutive...
ObjectiveTo analyze the role of PCI variation (Δ-PCI) before and after neoadjuvant chemotherapy (NACT) in interval cytoreductive surgery (ICS) setting with aim to propose a scoring model for predicting both complete cytoreduction histopathologic response.MethodsA total 50 consecutive patients who underwent ICS at our institution were prospectively collected between January-2020 December-2023. was assessed exploratory ICS. The clinical histopathological response NACT determined by Δ-PCI CRS....
(1) Background: In 2018 FIGO reclassified tumors confined to the cervix larger than 4 cm as stage IB3. Although concurrent CTRT has been standard of care and surgery alternative, optimal management remains controversial due lack direct comparison between CTRT. (2) Methods: This prospective observational study investigated efficacy, safety oncologic outcomes nerve-sparing laparoscopic radical hysterectomy (nsLRH) for IB3 cervical cancer patients (IB3). From 2009 2023, underwent pelvic...
To analyze the role of PCI variation (Δ-PCI) before and after neoadjuvant chemotherapy (NACT) in an interval cytoreductive surgery (ICS) setting with aim to propose a scoring model for predicting both complete cytoreduction histopathologic response.
Around 70% of ovarian cancers are diagnosed at an advanced stage. The International Federation Gynecology and Obstetrics (FIGO) classification categorises retroperitoneal abdominal lymph node metastases, including pelvic, lumboaortic hepato-coeliac nodes, as stage IIIA1, whereas extra-
<h3>Introduction/Background</h3> To compare the IOTA Assessment of Different NEoplasias in adneXa (ADNEX) model, Ovarian-Adnexal Reporting and Data System (O-RADS) combined Simple Rules (SR) with Risk (SRR) assessment SR ADNEX model preoperative discrimination benign malignant adnexal masses (AM). <h3>Methodology</h3> We conducted a monocentric retrospective study performed between January-2018 to December-2021 which includes consecutive women AM. Surgery histology represented reference...